Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic
Keywords: Bifunctional ligands; Dmt-Tic pharmacophore; Opioid receptorsAcOEt, ethyl acetate; DAMGO, [D-Ala2,N-Me-Phe4,Gly-ol5]enkephalin; DMF, N,N-dimethylformamide; DMSO-d6, hexadeuteriodimethyl sulfoxide; Dmt, 2′,6′-dimethyl-l-tyrosine; HOBt, 1-hydroxybenzotriazo