Keywords: DN، نفروپاتی دیابتی; Ac-RPS, acidic residue polysaccharides; ALB, albumin; Al-RPS, alkalic-RPS; Ara, arabinose; GLU, blood glucose; CAT, catalase; CRE, creatinine; DN, diabetic nephropathy; En-RPS, enzymatic-RPS; GC, gas chromatography; Glu, glucose; Gal, galactose; GSH-Px, G
مقالات ISI DN، نفروپاتی دیابتی (ترجمه نشده)
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Keywords: DN، نفروپاتی دیابتی; ROS, reactive oxygen species; DN, diabetic nephropathy; GBM, glomerular basement membraneInsulin; Podocyte; Autophagy; Reactive oxygen species; Filtration barrier permeability
Keywords: DN، نفروپاتی دیابتی; DN, diabetic nephropathy; eNOS, endothelial nitric oxide synthase; NMR, nuclear magnetic resonance; TCA, tricarboxylic acid; ACR, albumin-to-creatinine ratio; STZ, streptozotocin; NOE, nuclear Overhauser effect; PCA, principal component analysisUrinary me
Keywords: DN، نفروپاتی دیابتی; AII, angiotensin II; ACE, angiotensin converting enzyme; ACEI, angiotensin converting enzyme inhibitor; AGE, advanced glucose end substance; AII-RB, angiotensin II receptor blocker; BG, blood glucose; BW, body weight; DN, diabetic nephropathy; ECM, extrac
Keywords: DN، نفروپاتی دیابتی; TCM, traditional Chinese medicine; DN, diabetic nephropathy; RCT, randomized controlled clinical trial; CBM, Chinese biomedical literature database; CNKI, Chinese academy of sciences database; CDMD, Chinese doctoral dissertation full-text databaseTraditio
Puerarin, isolated from Pueraria lobata (Willd.), protects against diabetic nephropathy by attenuating oxidative stress
Keywords: DN، نفروپاتی دیابتی; PR, puerarin; DN, diabetic nephropathy; STZ, streptozotocin; FBG, fasting blood glucose; BUN, blood urea nitrogen; Scr, serum creatinine; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α;; ROS, reactive oxygen species; MnSOD, manganese superoxide dismu
Low molecular weight fucoidan modulates P-selectin and alleviates diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; DM, diabetes mellitus; DN, diabetic nephropathy; ECM, extracellular matrix; GBM, glomerular basement membrane; HE, hematoxylin and eosin; HRP, horse radish peroxidase; ICAM-1, intercellular adhesion molecule-1; IL-6, interleukin-6; IHC, immunohistochemist
Relationship between vitamin D status and vascular complications in patients with type 2 diabetes mellitus
Keywords: DN، نفروپاتی دیابتی; Vitamin D; Peripheral neuropathy; Nephropathy; Microvascular complication; Type 2 diabetes mellitus25(OH)D, 25-hydroxyvitamin D; BMI, body mass index; CV, cardiovascular; DN, diabetic nephropathy; DPN, diabetic peripheral neuropathy; DR, diabetic retinopa
Synergistic effects of c-Jun and SP1 in the promotion of TGFβ1-mediated diabetic nephropathy progression
Keywords: DN، نفروپاتی دیابتی; DM, diabetes mellitus; DN, diabetic nephropathy; ESRD, end-stage renal disease; ECM, extracellular matrix; TGFβ1, transforming growth factor-β1; HRMCs, human renal mesangial cells; ROS, reactive oxygen species; α-SMA, α-smooth muscle actin; Nrf2, nuclear
Paeoniflorin inhibits high glucose-induced macrophage activation through TLR2-dependent signal pathways
Keywords: DN، نفروپاتی دیابتی; PF, paeoniflorin; TLR2, toll like-receptor 2; DN, diabetic nephropathy; BMDM, bone marrow derived macrophages; iNOS, inducible nitric oxide synthase; MyD88, myeloid differentiation primary response gene 88; Trif, TIR-domain-containing adapter-inducing int
Histone methyltransferase Suv39h1 attenuates high glucose-induced fibronectin and p21WAF1 in mesangial cells
Keywords: DN، نفروپاتی دیابتی; Suv39h1, Suppressor of variegation 3–9 homolog 1; DN, diabetic nephropathy; H3K9me3, trimethylated lysine 9 of histone H3; HG, high glucose; HMT, histone lysine methyltransferase; PI3K, phosphoinositide 3-kinase; TGFβ, transforming growth factor-β; ERK, e
Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus
Keywords: DN، نفروپاتی دیابتی; Podocytes; Carboxymethyl lysine; NF-kB; ZEB2; E-cadherin; Diabetic nephropathyAGEs, advanced glycation end-products; RAGE, receptor for AGEs; CML, N-carboxymethyl-lysine; KLH, keyhole limpet hemocyanin; DM, diabetic mellitus; DN, diabetic nephropathy; EMT
Antioxidant diet and sex interact to regulate NOS isoform expression and glomerular mesangium proliferation in Zucker diabetic rat kidney
Keywords: DN، نفروپاتی دیابتی; AO, antioxidant; DN, diabetic nephropathy; ECM, extracellular matrix; Enos, endothelial nitric oxide synthase; ESRD, end stage renal disease; GTA, glomerular tuft area; IHC, immunohistochemistry; iNOS, inducible nitric oxide synthase; nNOS, neuronal nitri
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy
Keywords: DN، نفروپاتی دیابتی; α-SMA, α-Smooth muscle actin; DCM, diabetic cardiomyopathy; DM, Diabetes mellitus; DN, diabetic nephropathy; EF, Ejection fraction; ECM, Extra cellular matrix; FS, fractional shortening; IL-1β, Interleukin-1β; LV, Left ventricle; LVEDD, Left ventricular e
Strategy of integrated evaluation on treatment of traditional Chinese medicine as ‘interaction of system to system’ and establishment of novel fuzzy target contribution recognition with herb-pairs, a case study on Astragali Radix-Fructus Corni
Keywords: DN، نفروپاتی دیابتی; Traditional chinese medicine; Pharmacological evaluation system; Fuzzy target contribution recognition; Diabetic nephropathy; NFE2L2 activation-dependent pathwayTCM, traditional Chinese medicine; DN, diabetic nephropathy; ESRD, end-stage renal disease; RO
Linkage disequilibrium with HLA-DRB1-DQB1 haplotypes explains the association of TNF-308G>A variant with type 1 diabetes in a Brazilian cohort
Keywords: DN، نفروپاتی دیابتی; ANOVA, analysis of variance; CI, confidence interval; DN, diabetic nephropathy; DNA, deoxyribonucleic acid; GAD, glutamic acid decarboxylase; HbA1C, glycated hemoglobin; HDL, high density lipoprotein; HLA, human leukocyte antigen; HWE, Hardy–Weinberg equi
Polymorphic differences in the SOD-2 gene may affect the pathogenesis of nephropathy in patients with diabetes and diabetic complications
Keywords: DN، نفروپاتی دیابتی; T1DM, type one diabetes mellitus; T2DM, type two diabetes mellitus; IDDM, insulin dependent diabetes mellitus; DMI, diabetic myocardial infarction; DC, diabetic control; DN, diabetic nephropathy; DR, diabetic retinopathy; SD, diabetic patients with short
Glycated albumin triggers fibrosis and apoptosis via an NADPH oxidase/Nox4-MAPK pathway-dependent mechanism in renal proximal tubular cells
Keywords: DN، نفروپاتی دیابتی; GA; Tubulointerstitial fibrosis; Apoptosis; MAPK pathway; NADPH oxidase; Nox4GA, glycated albumin; DN, diabetic nephropathy; ROS, reactive oxygen species; OSS, oxidative stress; ECM, extracellular matrix; Apo-, apocynin; FN, fibronectin; AS-IV, Astragalos
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells
Keywords: DN، نفروپاتی دیابتی; AGEs, advanced glycation-end products; ARE, anti-oxidant response element; BSA, bovine serum albumin; DN, diabetic nephropathy; ECM, extracellular matrix; EMSA, electrophoretic mobility shift assay; FN, fibronectin; GMCs, glomerular mesangial cells; HG, h
Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis
Keywords: DN، نفروپاتی دیابتی; 3-MA, 3-methyladenine; AMPK, adenosine monophosphate-activated protein kinase; CIMP, conditionally immortalized mouse podocyte; DN, diabetic nephropathy; HG, high glucose; HO-1, heme oxygenase-1; mTOR, mammalian target of rapamycin; NG, normal glucoseAuto
Reduced LRP6 expression and increase in the interaction of GSK3β with p53 contribute to podocyte apoptosis in diabetes mellitus and are prevented by green tea
Keywords: DN، نفروپاتی دیابتی; AER, albumin excretion rate; ANOVA, analysis of variance; BIO, (2′Z,3′E)-6-bromoindirubin-3′-oxime; CO2, carbon dioxide; CTGF, connective tissue growth factor; DM, diabetes mellitus; DN, diabetic nephropathy; ESRD, end-stage renal disease; FBS, fetal bovi
Associations study of vitamin D receptor gene polymorphisms with diabetic microvascular complications: a meta-analysis
Keywords: DN، نفروپاتی دیابتی; DMI, diabetic microvascular complications; VDR, vitamin D receptor; OR, odds ratios; CI, confidence intervals; DR, diabetic retinopathy; DN, diabetic nephropathy; SNP, single nucleotide polymorphism; HWE, Hardy–Weinberg equilibriumVitamin D receptor; Diab
Gymnemasylvestre derived compounds inhibit GSH depletion and increase cGMP and nitric oxide to attenuate advanced glycation end products induced hypertrophic growth in renal tubular epithelial cells
Keywords: DN، نفروپاتی دیابتی; AGE, advanced glycation end products; NO, nitric oxide; cGMP, cyclic guanosine monophosphate; DN, diabetic nephropathy; GE, Gymnemasylvestre organic extract; GSH, reduced glutathione; MDA, malondialdehyde; SOD, superoxide dismutase; CAT, catalase; GPx, gl
Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts
Keywords: DN، نفروپاتی دیابتی; DN, diabetic nephropathy; TGF-β, transforming growth factor-β; HG, high glucose; ERK, extracellular signal-regulated kinase; TGF-βR, TGF-β receptor; FGF23, fibroblast growth factor 23; DMEM, Dulbecco’s Modified Eagle Medium; SDS, sodium dodecyl sulfate; F
High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway
Keywords: DN، نفروپاتی دیابتی; Cdk, Cyclin-dependent kinase; DN, Diabetic nephropathy; Egr, Early growth response; ERK, Extracellular signal-regulated kinase; MEK, Mitogen-activated protein kinase/ERK kinase; siRNA, Small interference RNA; TGF-β1, Transforming growth factor-β1.Cdk5; TG
RhoA/rho kinase signaling reduces connexin43 expression in high glucose-treated glomerular mesangial cells with zonula occludens-1 involvement
Keywords: DN، نفروپاتی دیابتی; Cx43, connexin43; Cx43-CT, Cx43-c-terminal; DN, diabetic nephropathy; FN, fibronectin; GJIC, gap junctional intercellular communication; GMCs, glomerular mesangial cells; NF-κB, nuclear factor kappa-B; ROCK, Rho kinase; S1P, sphingosine-1-phosphate; ZO-1,
Lipid accumulation is ahead of epithelial-to-mesenchymal transition and therapeutic intervention by acetyl-CoA carboxylase 2 silence in diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; ACC2, acetyl-CoA carboxylase 2; p-ACC2, phosphorylated acetyl-CoA carboxylase 2; DM, diabetes mellitus; DN, diabetic nephropathy; ESRD, End Stage Renal Disease; FFAs, free fatty acids; SREBP-1, sterol regulatory element binding protein-1; PPARs, peroxisom
Endothelial nitric oxide synthase (eNOS) 4b/a polymorphism and the risk of diabetic nephropathy in type 2 diabetes mellitus: A meta-analysis
Keywords: DN، نفروپاتی دیابتی; eNOS, endothelial nitric oxide synthase; DN, diabetic nephropathy; ESRD, end-stage renal disease; ACE, angiotensin-converting enzyme; MTHFR, methylenetetrahydrofolate reductase; CNKI, China National Knowledge Infrastructure; OR, odds ratio; CI, confidence
MTHFR 677 T variant contributes to diabetic nephropathy risk in Caucasian individuals with type 2 diabetes: A meta-analysis
Keywords: DN، نفروپاتی دیابتی; DN, diabetic nephropathy; ESRD, end-stage renal disease; HWE, Hardy–Weinberg equilibrium; MTHFR, methylenetetrahydrofolate reductase; OR, odds ratio; 95% CI, 95% confidence interval.Diabetic nephropathy; Meta-analysis; Polymorphism; MTHFR C677T
The Function of MicroRNAs in Renal Development and Pathophysiology
Keywords: DN، نفروپاتی دیابتی; MicroRNA; Renal development; Renal pathophysiologyAKI, acute kidney injury; AR, acute rejection; CKD, chronic kidney disease; DN, diabetic nephropathy; MET, mesenchymal-epithelial transition; miRNA, microRNA; PKD, polycystic kidney disease; RCC, renal cel
Activation of RhoA/ROCK regulates NF-κB signaling pathway in experimental diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; ROCK, Rho kinase; DN, diabetic nephropathy; NF-κB, nuclear factor-kappa B; GMCs, glomerular mesangial cells; STZ, streptozocin; ICAM-1, intercellular adhesionmolecule-1; TGF-β1, transforming growth factor-beta 1; ECM, extracellular matrix; MYPT, myosin ph
Sphingosine-1-phosphate: A Janus-faced mediator of fibrotic diseases
Keywords: DN، نفروپاتی دیابتی; BAL, bronchoalveolar lavage; BMSC, bone marrow-derived stem cell; CCl4, carbon tetrachloride; Col, collagen; CTGF, connective tissue growth factor; DN, diabetic nephropathy; EC, epithelial cell; ERK, extracellular signal-regulated kinase; FB, fibroblast;
Proteomic analysis of kidney and protective effects of grape seed procyanidin B2 in db/db mice indicate MFG-E8 as a key molecule in the development of diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; AGEs, advanced glycation end products; BUN, blood urea nitrogen; Cr, plasma creatinine concentration; DM, diabetes mellitus; DN, diabetic nephropathy; ERK1/2, extracellular signal-regulated kinase1/2; ESRD, end-stage renal disease; FBG, fasting blood gluc
Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells
Keywords: DN، نفروپاتی دیابتی; DN, diabetic nephropathy; ROS, reactive oxygen species; ∆Ψm, mitochondrial membrane potential; ATP, adenosine-5′-triphosphate; mtDNA, mitochondrial DNA; SIRT1, sirtin 1; UCP1, uncoupling protein-1; MnSOD, manganese superoxide dismutase; PKC, protein kinas
Modulation of AT-1R/MAPK cascade by an olmesartan treatment attenuates diabetic nephropathy in streptozotocin-induced diabetic mice
Keywords: DN، نفروپاتی دیابتی; ACE-2, angiotensin converting enzyme-2; Ang-(1–7) mas R, angiotensin-(1–7) mas receptor; Ang-II, angiotensin-II; AT-1R, Ang-II type 1 receptor; DN, diabetic nephropathy; NADPH oxidase, nicotinamide adenine dinucleotide phosphate oxidase; p-JNK, phospho-c-
Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; AGEs, advanced glycation end products; RAGE, receptor for advanced glycation end products; T2DM, type 2 diabetes mellitus; DR, diabetic retinopathy; DN, diabetic nephropathy; HWE, hardy–Weinberg equilibrium; OR, odds ratio; CI, confidence interval; FEM, f
Polydatin ameliorates experimental diabetes-induced fibronectin through inhibiting the activation of NF-κB signaling pathway in rat glomerular mesangial cells
Keywords: DN، نفروپاتی دیابتی; NF-κB, nuclear factor-kappa B; DN, diabetic nephropathy; ECM, extracellular matrix; FN, fibronectin; GMCs, glomerular mesangial cells; ICAM-1, intercellular adhesionmolecule-1; TGF-β1, transforming growth factor-beta; STZ, Streptozocin; PDTC, pyrrolidined
Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration
Keywords: DN، نفروپاتی دیابتی; CN1, Carnosinase 1; CNDP1, Carnosinase 1 gene; HPLC, high performance liquid chromatography; ELISA, enzyme-linked immunosorbent assay; DN, diabetic nephropathy; ACE, angiotensin converting enzyme; TGF, transforming growth factorHistidine dipeptides; Carno
Megalin is downregulated via LPS-TNF-α-ERK1/2 signaling pathway in proximal tubule cells
Keywords: DN، نفروپاتی دیابتی; AT1R, angiotensin II type 1 receptor; CVD, cardiovascular disease; DN, diabetic nephropathy; GPx3, glutathione peroxidase 3; IRPTC, immortalized rat proximal tubule cell; LPS, lipopolysaccharide; PTC, proximal tubule cell; TCA, trichloroacetic acidDiabeti
Renal expression of proto-oncogene Ets-1 on matrix remodeling in experimental diabetic nephropathy
Keywords: DN، نفروپاتی دیابتی; α-SMA, α-Smooth muscle actin; CKD, Chronic kidney disease; Ccr, Creatinine clearance; DN, Diabetic nephropathy; ECM, Extracellular matrix; MMP, Matrix metalloproteinase; STZ, Streptozotocin; TIMP, Tissue inhibitor of matrix metalloproteinase; Upro, Urine
Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity
Keywords: DN، نفروپاتی دیابتی; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; BUN, blood urea nitrogen; CAT, catalase; Ccr, creatinine clearance; DN, diabetic nephropathy; GBM, glomerular base membrane; MDA, malondialdehyde; MF, metformin HCl; ROS, reactive oxygen species; Scr, serum creatinine;
Cytochrome P450 epoxygenase CYP2J2 attenuates nephropathy in streptozotocin-induced diabetic mice
Keywords: DN، نفروپاتی دیابتی; AG1478, N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine; AA, arachidonic acid; α-SMA, alpha-smooth muscle actin; CYP, cytochrome P450; DHET, dihydroxyeicosatrienoic acid; DN, diabetic nephropathy; DMEM/F12, Dulbecco's modified Eagle's and Ham F12 mediu
Prevalence of non-diabetic renal disease in patients with type 2 diabetes
Keywords: DN، نفروپاتی دیابتی; NDRD, non-diabetic renal diseases; DN, diabetic nephropathy; IMT, intima-media thickening; EF, ejection fraction; LVMI, left ventricle mass index; LVH, left ventricle hypertrophyDiabetic nephropathy; Non-diabetic renal disease; Fasting blood glucose; Diab
p38 MAPK pathway is involved in high glucose-induced thioredoxin interacting protein induction in mouse mesangial cells
Keywords: DN، نفروپاتی دیابتی; TXNIP, thioredoxin interacting protein; TRX, Thioredoxin; HG, high glucose; MMC, mouse mesangial cell; DN, diabetic nephropathy; MAPK, mitogen-activated protein kinase; ROS, reactive oxygen speciesHigh glucose; Thioredoxin interacting protein; p38 mitogen
Cinnamaldehyde impairs high glucose-induced hypertrophy in renal interstitial fibroblasts
Keywords: DN، نفروپاتی دیابتی; α-SMA, α-smooth muscle actin; DN, diabetic nephropathy; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; HG, high glucose; HM, high mannitol; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase; LDH, lactate dehydrogenase; MAPK, mitog
Zhen-wu-tang, a blended traditional Chinese herbal medicine, ameliorates proteinuria and renal damage of streptozotocin-induced diabetic nephropathy in rats
Keywords: DN، نفروپاتی دیابتی; ZWT, hen-wu-tang; DN, diabetic nephropathy; STZ, streptozotocin; BUN, blood urea nitrogen; RIA, radioimmunoassay; Cr, creatinineZhen-wu-tang; Diabetic nephropathy; Proteinuria; Podocyte; Nephrin; Podocin
Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats
Keywords: DN، نفروپاتی دیابتی; Diabetic nephropathy; Total glucosides of paeony; Paeonia lactiflora; Oxidative stress; Nitrotyrosine; NF-κB; Mitogen activated protein kinaseTGP, Total glucosides of paeony; DN, Diabetic nephropathy; STZ, Streptozotocin; MDA, Malondialdehyde; 3-NT, 3-nit
Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells
Keywords: DN، نفروپاتی دیابتی; Thyroid hormone binding protein; μ-Crystallin; CRYM; Diabetic nephropathy; Hyperglycemia; Oxidative stressTHBP, thyroid hormone binding protein/μ-crystallin; CRYM, crystallin M; ROS, reactive oxygen species; DN, diabetic nephropathy; HG, high glucose/25 m
Effect of Lactobacillus reuteri GMNL-263 treatment on renal fibrosis in diabetic rats
Keywords: DN، نفروپاتی دیابتی; α-SMA, α-smooth muscle actin; DN, diabetic nephropathy; ECM, extracellular matrix; ERK, extracellular signal-regulated kinase; JAK2, Janus kinase 2; JNK, c-Jun N-terminal kinase; MAPK, mitogen-activated protein kinase; PAI-1, plasminogen activator inhibit
Different expression of Fibrinopeptide A and related fragments in serum of type 1 diabetic patients with nephropathy
Keywords: DN، نفروپاتی دیابتی; IDDM, insulin-dependent diabetes mellitus; T1D, type 1 diabetes; T2D, type 2 diabetes; DN, diabetic nephropathy; T1DN, type 1 diabetic nephropathy; T2DN, type 2 diabetic nephropathy; ROC, receiver operating curve; FWHM, full-width half-height maximumClinP