Keywords: African swine fever virus (ASFV); DNA replication; BrdU pulse; DNA damage response (DDR); Ataxia telangiectasia mutated rad-3 related (ATR) pathway; Subnuclear domains
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Efficient repair of DNA double strand breaks in individuals from high level natural radiation areas of Kerala coast, south-west India
Keywords: Normal level natural radiation area (NLNRA); High level natural radiation area (HLNRA); Peripheral blood mono-nuclear cells (PBMCs); Chronic low dose radiation; DNA damage response (DDR); Non-homologous end joining (NHEJ); Homologous recombination (HR);
Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics
Keywords: 53BP1; tumor suppressor p53 binding protein 1; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia and Rad3-related; Chk; checkpoint kinase; DSB; DNA double-strand break; DDR; DNA damage response; DNA-PKcs; DNA-dependent protein kinase, catalyt
PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells
Keywords: DNA damage response (DDR); Cyclic adenosine monophosphate (cAMP); AKT (PKB); Mdm2; p53; NF-κB;
Role of MERIT40 in stabilization of BRCA1 complex: A protein-protein interaction study
Keywords: BRCA1-complex stability; MERIT40; RAP80; DNA damage response (DDR);
A direct role for small non-coding RNAs in DNA damage response
Keywords: DNA damage response (DDR); non-coding RNA (ncRNA); DDRNA; diRNA; DICER; DROSHA
Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation
Keywords: ERK1/2 kinases; DNA damage repair; Non-homologous end joining (NHEJ); DNA damage response (DDR); Ku; DNA-PKcs;
ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation
Keywords: ERK1/2 kinases; DNA damage response (DDR); ATR; CDC2; S arrest
Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells
Keywords: Mevalonate pathway; Small GTPases; Anticancer drugs; DNA damage response (DDR); Sarcoma cellsATM, ataxia telangiectasia mutated; ATR, ATM and Rad3-related; Chk, checkpoint kinase; DDR, DNA damage response; ERK, extracellular regulated kinase; H2AX, histon
Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
Keywords: ERK1/2 kinases; DNA damage response (DDR); ATM; CHK2; CDC25C; G2/M arrest;
Importance of DNA damage checkpoints in the pathogenesis of human cancers
Keywords: DNA damage response (DDR); Cell cycle; Checkpoint control; Cancer; Cell cycle regulators; MAPK's