دانلود مقالات ISI درباره DNMT1، DNA methyltransferase 1 + ترجمه فارسی

هدف قرار دادن متیلاسیون لیسین هیستون در سرطان

Targeting histone lysine methylation in cancer

Keywords: DNMT1، DNA methyltransferase 1; Methyltransferase; Demethylase; Chromatin; Epigenetic therapy; Histone methylation; Methyltransferase inhibitor2-OG, 2-Oxoglutarate; AML, Acute Myeloid Leukemia; CML, Chronic Myelogenous Leukemia; DNMT1, DNA Methyltransferase 1; DLBCL, Diffuse Large B-cel

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

تنظیم کننده های کروماتین در توسعه عصبی

Chromatin regulators of neural development

Keywords: DNMT1، DNA methyltransferase 1; 5hmC, 5-hydroxymethylcytosine; 5mC, 5-methylcytosine; BDNF, brain-derived neurotrophic factor; Chd1, chromodomain–helicase–DNA-binding protein 1; CPN, callosal projection neuron; ctip2, (COUP-TF)-interacting protein 2; DNMT1, DNA methyltransferase 1; ESC,

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

مکانیزم های مولکولی برای مهار سلول های سرطانی روده بزرگ با اپیگنوکاتچین گالات و بوتیرات سدیم

Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate

Keywords: DNMT1، DNA methyltransferase 1; EGCG, epigallocatechin gallate; NaB, sodium butyrate; HDAC, histone deacetylase; HAT, histone acetyltransferase; DMSO, dimethylsulfoxide; DNMT1, DNA methyltransferase 1; DNMT3A, DNA methyltransferase 3A; γ-H2AX, gamma-H2A histone family member X; NF-κB, n

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

تغییرات ماده سفید و تغییرات گلیال در 5 هیدروکسی متیل سیتوزین پس از هیپرفرفیون مزمن مغزی

White matter tract and glial-associated changes in 5-hydroxymethylcytosine following chronic cerebral hypoperfusion

Keywords: DNMT1، DNA methyltransferase 1; CC1, adenomatous polyposis coli; CNS, central nervous system; DIV, days in vitro; DNMT1, DNA methyltransferase 1; GFAP, glial fibrillary acidic protein; HCl, hydrochloric acid; HDAC1, histone deacetylase 1; H&E, haemotoxylin and eosin; 5hmC, 5-hydroxymeth

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

نقش میکرو RNA ها در بیان HLA-G در تومورهای انسانی

Role of microRNAs on HLA-G expression in human tumors

Keywords: DNMT1، DNA methyltransferase 1; AML, acute myeloid leukemia; APC, antigen presenting cells; CTL, cytotoxic T lymphocyte; DAC, 5-aza-2′-deoxycytidine; DNMT1, DNA methyltransferase 1; HCC, hepatocellular carcinoma; IFN, interferon; IHC, immunohistochemistry; lnRNA, long non-coding RNA; MH

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Expression analyses of splice variants of zebrafish cyclin-dependent kinase-like 5 and its substrate, amphiphysin 1

Keywords: DNMT1، DNA methyltransferase 1; Amph1, amphiphysin 1; BAR, Bin-Amphiphysin-Rvs; CDKL5, cyclin-dependent kinase-like 5; CLAP, clathrin/AP-2 binding; DAPI, 4′,6-diamidino-2-phenylindole; DMEM, Dulbecco's modified Eagle's medium; Dnmt1, DNA methyltransferase 1; GST, glutathione S-transfera

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic drift towards histone modifications regulates CAV1 gene expression in colon cancer

Keywords: DNMT1، DNA methyltransferase 1; AZA, 5-Aza-2′-deoxycytidine; CAV1, Caveolin-1; DNMT1, DNA methyltransferase 1; SAM, S-adenosyl-l-methionin; TSA, trichostatin A; SFN, sulforaphen; H3K4me3, histone 3 lysine 4 trimethylation; H3K9me3, histone 3 lysine 9 trimethylation; H3K9AcS10p, histone

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance

Keywords: DNMT1، DNA methyltransferase 1; ABCB1, P-glycoprotein; ABCC1, multidrug resistance-associated protein; AP-1, activator protein 1; CSA, cyclosporine A; DFO, desferrioxamine; DNMT1, DNA methyltransferase 1; ERK, extracellular signal-regulated kinase; GST, glutathione S-transferase; IRP1,

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

DNMT1 activates the canonical Wnt signaling in rheumatoid arthritis model rats via a crucial functional crosstalk between miR-152 and the DNMT1, MeCP2

Keywords: DNMT1، DNA methyltransferase 1; RA, rheumatoid arthritis; miRNA, microRNA; DNMT1, DNA methyltransferase 1; MeCP2, methyl CpG binding protein 2; ChIP, chromatin immunoprecipitation; 5-azadC, 5-aza-2′-deoxycytidine; SFRP, secreted frizzled-related protein; FLS, fibroblast-like synoviocyte

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Arsenic exposure disrupts epigenetic regulation of SIRT1 in human keratinocytes

Keywords: DNMT1، DNA methyltransferase 1; As(III), inorganic arsenite; NMSC, non-melanoma skin cancer; H4K16, histone 4 lysine 16; NHEK, normal human epidermal keratinocyte; MNase, micrococcal nuclease; DNMT1, DNA methyltransferase 1; PRG, polycomb repressive group complexArsenic; Sirtuin 1; MiR-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Increasing role of UHRF1 in the reading and inheritance of the epigenetic code as well as in tumorogenesis

Keywords: DNMT1، DNA methyltransferase 1; DNMT1, DNA methyltransferase 1; PARP, Poly (ADP-ribose) polymerase; RING, Really Interesting New Gene; SRA, SET and RING-finger associated domain; TTD, tandem tudor domain; UHRF1, ubiquitin-like containing PHD and RING finger domains, 1; VEGF, vascular en

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

DNA methyltransferase 1 is essential for initiation of the colon cancers

Keywords: DNMT1، DNA methyltransferase 1; CSC, cancer stem-like cell; CIC, cancer-initiating cell; DNMT1, DNA methyltransferase 1; SP, side population; MP, main populationCancer stem cell; Colon cancer; DNMT1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Impaired DNA repair and genomic stability in hereditary tyrosinemia type 1

Keywords: DNMT1، DNA methyltransferase 1; 18S, 18S rRNA; BER, base excision repair; cDNA, DNA complementary to RNA; CIN, chromosomal instability mutator phenotype; Creat, creatinine; DNA, deoxyribonucleic acid; DNMT1, DNA methyltransferase 1; dNTP, deoxyribonucleotide triphosphate; DTT, dithiothr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Glucocorticoid-induced loss of DNA methylation in non-neuronal cells and potential involvement of DNMT1 in epigenetic regulation of Fkbp5

Keywords: DNMT1، DNA methyltransferase 1; Fkbp5, FK506 binding protein 5; DNAm, DNA methylation; Dnmt1, DNA methyltransferase 1; HPA-axis, hypothalamic–pituitary–adrenal axis; CS, Cushing’s syndrome; GC, glucocorticoid; DEX, dexamethasoneFkbp5; Dnmt1; Epigenetics; DNA methylation; AtT-20; Pituita

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation in Laryngeal carcinoma

Keywords: DNMT1، DNA methyltransferase 1; HNSCC, head and neck squamous cell carcinoma; NNK, 4-(methylnitro-samino)-1-(3-pyridyl)-1-butanone; TSGs, tumor suppressor genes; IHC, immunohistochemistry; DNMT1, DNA methyltransferase 1; RT-PCR, reverse transcription polymerase chain reaction; HPV, huma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Circulating microRNAs as candidate biomarkers in patients with systemic lupus erythematosus

Keywords: DNMT1، DNA methyltransferase 1; DMARDs, disease-modifying antirheumatic drugs; DNMT1, DNA methyltransferase 1; ERK pathway signaling, extracellular signal-regulated kinase pathway signaling; HCs, healthy controls; IFN, interferon; IRF-5, IFN regulatory factor 5; KLF13, Kruppel-like fact

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The mesenchyme in malignancy: A partner in the initiation, progression and dissemination of cancer

Keywords: DNMT1، DNA methyltransferase 1; αSMA, alpha smooth muscle actin; Bmp, bone morphogenetic protein; Dkk, Dikkopf; Dnmt1, DNA methyltransferase 1; DT, diphtheria toxin; ECM, extracellular matrix; Fgf2, fibroblast growth factor-2; Ihh, Indian hedgehog; ISEMF, intestinal subepithelial myofib

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular mechanism underlying the differential MYF6 expression in postnatal skeletal muscle of Duroc and Pietrain breeds

Keywords: DNMT1، DNA methyltransferase 1; MYF6, myogenic factor 6; MRF, myogenic regulatory factor; 5′-UTR, 5′-untranslated region; TFBS, transcription factor binding site; RT-PCR, reverse transcription PCR; BSP, bisulfite sequencing PCR; DNMT1, DNA methyltransferase 1; NTC, no template control;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases

Keywords: DNMT1، DNA methyltransferase 1; Ago, Argonaute; AID, activation-induced cytidine deaminase; AML-1, acute myeloid leukaemia-1; CDK-2, cyclin-dependent kinase 2; CNS, central nervous system; DGCR8, DiGeorge syndrome critical region protein 8; DNMT1, DNA methyltransferase 1; EAE, experimen

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Age-dependent decreases in DNA methyltransferase levels and low transmethylation micronutrient levels synergize to promote overexpression of genes implicated in autoimmunity and acute coronary syndromes

Keywords: DNMT1، DNA methyltransferase 1; Aging; Epigenetics; DNA methylation; Senescence; NutritiondmC, deoxymethylcytosine; Dnmt1, DNA methyltransferase 1; EHNA, erythro-9-(2-hydroxy-3-nonyl)adenine; Hcy, homocysteine; HBSS, Hanks balanced salt solution; mC, 5-methylcytosine; Met, methionine; N

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity

Keywords: DNMT1، DNA methyltransferase 1; DNMT1, DNA methyltransferase 1; H2AK5, lysine 5 of histone H2A; HDAC1, histone deacetylase 1; Tip60, Tat-interactive protein of 60 kDa; UHRF1, Ubiquitin-like PHD, Ringer Finger 1DNMT1; Epigenetic; Histone H2A; Tip60; UHRF1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

HDACi – Targets beyond chromatin

Keywords: DNMT1، DNA methyltransferase 1; AML1-ETO, acute myeloid leukemia 1-eight-twenty-one; Bcr–Abl, breakpoint cluster region–abelson murine leukemia; CBP, CREB-binding protein; DNMT1, DNA methyltransferase 1; c-Raf, rat fibrosarcoma; FLT3, FMS-like tyrosine kinase 3; FoxO1, forkhead box 1; H

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

HBx genotype D represses GSTP1 expression and increases the oxidative level and apoptosis in HepG2 cells

Keywords: DNMT1، DNA methyltransferase 1; HBV; HBx; DNA methylation; GSTP1; HepG2; HepG2.2.15HBV, hepatitis B virus; HBx, hepatitis B virus X; HCC, hepatocellular carcinoma; GSTP1, glutathione S-transferase P1; ROS, reactive oxygen species; DNMT1, DNA methyltransferase 1; MEM, minimal essential m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cyclin-dependent kinase-like 5 binds and phosphorylates DNA methyltransferase 1

Keywords: DNMT1، DNA methyltransferase 1; CDKL5, cyclin-dependent kinase-like 5; DMEM, Dulbecco’s modified Eagle’s medium; Dnmt1, DNA methyltransferase 1; GST, glutathione S-transferase; IPTG, isopropyl β-d-galactoside; MeCP2, methyl-CpG-binding protein 2; PMSF, phenylmethylsulfonyl fluorideDNA m

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Temporary consumption of diet with unbalanced amino acid pattern affects long-lasting growth retardation correlated with oxidative stress response associated gene expression in juvenile pigs

Keywords: DNMT1، DNA methyltransferase 1; Soy protein; Oxidative stress; Hepatic gene expression; Growth; Juvenile pig; ‘Metabolic programming’ALOX12, arachidonate-12-lipoxigenase; APOA1, apolipoprotein AI; CAS, casein; CANX, calnexin; DNMT1, DNA methyltransferase 1; EP24.16, endopeptidase 24.16;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

The UHRF family: Oncogenes that are drugable targets for cancer therapy in the near future?

Keywords: DNMT1، DNA methyltransferase 1; Dnmt1, DNA methyltransferase 1; HAT, histone acetyltransferase; HDAC1, histone deacetylase 1; ICBP90, inverted CCAAT box binding protein of 90 kDa; NIRF, Np95 ICBP90 ring finger; PHD, plant homeodomain; RING, really interesting new gene; SRA, set and ring

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Basic mechanisms for the control of germ cell gene expression

Keywords: DNMT1، DNA methyltransferase 1; TBP, TATA binding protein; TAF, TBP-associated factor; ALF, TFIIAαβ-like factor; TRF, TBP-related factor; LTR, long terminal repeat; Dnmt1, DNA methyltransferase 1; CREM, cyclic AMP responsive element modulator; UTR, untranslated regionGene expression; Tr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه