Polymer–lipid hybrid nanoparticles synchronize pharmacokinetics of co-encapsulated doxorubicin–mitomycin C and enable their spatiotemporal co-delivery and local bioavailability in breast tumor
Keywords: AKR, aldo-keto reductase; AUC, area under the curve; CL, total body clearance; cTnI, cardiac troponin I; DMPLN, doxorubicin and mitomycin C co-loaded polymer–lipid hybrid nanoparticles; DOX, doxorubicin; DOXOL, doxorubicinol; EPR, enhanced permeability an