Keywords: 8-OHdG; 8-oxo-2â²-deoxyguanosine; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocator; Bad; Bcl2-associated agonist of cell death; BKA; bongkrekic acid; CAT; catalase; CsA; cyclosporine A; Cu/Zn-SOD; Cu/Zn-superoxide dismutase; DR4;
مقالات ISI (ترجمه نشده)
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Keywords: Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
Keywords: AhR; aryl hydrocarbon receptor; ARE; antioxidant response element; BT; black tea; CYP; cytochrome P450; DME; drug-metabolizing enzymes; DR4; direct repeat with 4Â bp spacer; DRE; dioxin response elements; GT; green tea beverage; EC; epicatechin; EGC; epig
Keywords: ADAM; (a disintegrin and metalloprotease) metallopeptidase; ALPs; alkyl-lysophospholipids; CD24; signal transducer CD24 (glycosylphosphatidylinositol-anchored receptor); CD44; CD44 antigen (receptor for hyaluronic acid); CXCR4; chemokine receptor type 4;
Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo
Keywords: DR5; death receptor 5; DR4; death receptor 4; TNF; tumor necrosis factor; TRAIL; TNF-related apoptosis inducing ligand; scFv; single chain fragment variable; MTT; methyl thazoy terazolium; IPTG; isopropyl β-D-1-thiogalactopyranoside; PBS; phosphate buffe
Hepatitis B virus X protein and proinflammatory cytokines synergize to enhance TRAIL-induced apoptosis of renal tubular cells by upregulation of DR4
Keywords: Chip; chromatin immunoprecipitation; DR4; death receptor-4; DR5; death receptor-5; DLR; dual luciferase reporter; HBV; hepatitis B virus; HBx; hepatitis B virus X protein; HBV-GN; HBV-associated glomerulonephritis; IFN-γ; interferon gamma; NF-κB; nuclea
The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease
Keywords: ABC; ATP-Binding Cassette; DR4; direct repeat 4; ER; endoplasmic reticulum; HDL; high density lipoprotein; LDLR; low density lipoprotein receptor; LXR; Liver X Receptor; LXRE; LXR response element; NCoR; nuclear co-repressor; NPC1L1; Niemann-Pick C1-like
Selective dopamine receptor 4 activation mediates the hippocampal neuronal calcium response via IP3 and ryanodine receptors
Keywords: Intracellular calcium; Dopamine; DR4; IP3 receptor; Ryanodine;
Role of the liver X receptors in skin physiology: Putative pharmacological targets in human diseases
Keywords: ABCA1; ATP-binding cassette 1; ABCA12; ATP-binding cassette 12; ABCG1; ATP binding cassette subfamily G member 1; Apo; apolipoprotein; CAT; catalase; COX-2; cyclo-oxygenase-2; DR4; direct repeat 4; EGCG; epigallocatechin-3-gallate; ERK; extracellular sign
Melanoma-Directed Activation of Apoptosis Using a Bispecific Antibody Directed at MCSP and TRAIL Receptor-2/Death Receptor-5
Keywords: DR4; death receptor-4; DR5; death receptor-5; MCSP; melanoma-associated chondroitin sulfate proteoglycan; rhTRAIL; recombinant human soluble tumor necrosis factor-related apoptosis-inducing ligand; TRAIL; tumor necrosis factor-related apoptosis-inducing l
Research paperFerulic acid decreases cell viability and colony formation while inhibiting migration of MIA PaCa-2 human pancreatic cancer cells in vitro
Keywords: FA; Ferulic acid; CCND1; Cyclin D1; CDK4; Cyclin Dependent Kinase 4; CDK6; Cyclin Dependent Kinase 6; RB; Retinablastoma gene; BCL-XL; B-cell lymphoma-extra large; BID; BH3 Interacting Domain Death Agonist; DR4; HLA-DR4; DR5; Death receptor 5; FADD; Fas-A
Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways
Keywords: CHOP; CCAAT/enhancer-binding protein homologous protein; DR4, -5; death receptor 4, -5; ERK; extracellular signal-regulated kinase; p38 MAPK; p38 mitogen-activated protein kinase; JNK; c-Jun N-terminal kinase; PARP; poly-ADPribose polymerase; ROS; reactiv
DR4 communication in the South African context: A conceptual paper
Keywords: Communication management; Disaster risk reduction; DR4
Two death-inducing human TRAIL receptors to target in cancer: Similar or distinct regulation and function?
Keywords: TRAIL; DR4; DR5; Receptor preference; Apoptosis
Isoangustone A induces apoptosis in SW480 human colorectal adenocarcinoma cells by disrupting mitochondrial functions
Keywords: AMPK; AMP-activated protein kinase; BSA; bovine serum albumin; DCFH-DA; dichlorofluorescin diacetate; DR4; death receptor 4; ETC; electron transport chain; FBS; fetal bovine serum; HEGU; hexane/ethanol extract of Glycyrrhiza uralensis Fisch; IAA; isoangus
TRAIL mRNA expression in peripheral blood mononuclear cells of Egyptian SLE patients
Keywords: ANAs; antinuclear antibodies; Apo2L; apoptosis ligand 2; C3; complement; CBC; complete blood count; DcR1; decoy receptor 1; DR4; death receptor 4; dsDNA; double-stranded deoxyribonucleic acid antibodies; ESR; erythrocyte sedimentation rate; GAPDH; glycera
Relevance of signaling molecules for apoptosis induction on influenza A virus replication
Keywords: Akt; v-akt murine thymoma viral oncogene homolog 1; Apaf-1; apoptotic protease activating factor 1; Bax; Bcl-2-associated x protein; Bcl-2; B-cell lymphoma 2; BH; Bcl-2 homology; Caspases; cysteine-aspartic acid protease; DAP3; death-associated protein
Small molecule modulators of MHC class II antigen presentation: Mechanistic insights and implications for therapeutic application
Keywords: MHC; major histocompatibility complex; MHC II; MHC class II molecules; APC; antigen presenting cells; ER; endoplasmic reticulum; Ii; invariant chain; MIIC; MHC class II-containing compartment; HLA; human leukocyte antigen; DM; HLA-DM; DR; HLA-DR; DR1; DRA
Research ArticleHIV infection increases HCV-induced hepatocyte apoptosis
Keywords: HCV-HIV coinfection; Apoptosis; TRAIL receptor; JFH-1; Japanese Fulminant Hepatitis 1; TRAIL; TNF-related apoptosis-inducing ligand; PARP; poly (ADP-ribose)polymerase; TGF-β1; transforming growth factor beta1; DR4; Death receptor 4; DR5; death receptor
c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment
Keywords: c-Cbl; Casitas B-lineage lymphoma; DD; death domain; DISC; death-inducing signaling complex; DMEM; Dulbecco's modified Eagle's medium; DR4; TRAIL-R1; DR5; TRAIL-R2; DTT; dithiothreitol; EGF; epidermal growth factor; EGFR; EGF receptor; EGTA; ethylene glyc
Lipid raft connection between extrinsic and intrinsic apoptotic pathways
Keywords: APAF-1; apoptotic protease-activating factor-1; CASMER; clusters of apoptotic signaling molecule-enriched rafts; CTx; cholera toxin; DiOC6(3); 3,3â²-dihexyloxacarbocyanine iodide; DR4; death receptor 4; DR5; death receptor 5; DISC; death-inducing signali
KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway
Keywords: TRAIL; tumor necrosis factor-related apoptosis-inducing ligand; IAP; Inhibitor of apoptosis proteins; DR4; death receptor 4; DR5; death receptor 5; XIAP; X-linked inhibitor of apoptosis protein; ph-Akt; phosphorylated Akt; Glioma; TRAIL/Apo2L; KAAD-cyclop
Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosis
Keywords: apoptosis; azacitidine; carboplatin; DR4; ovarian cancer;
TRAIL receptor signalling and modulation: Are we on the right TRAIL?
Keywords: Apoptosis; Cancer; DR4; DR5; DcR1; DcR2; TRAIL; Clinical trials; Receptor-selective TRAIL variants; Agonistic antibodies
Expression of death receptor 4 induces caspase-independent cell death in MMS-treated yeast
Keywords: DR4; Caspase-independent; Yeast; DNA damage
TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
Keywords: TRAIL; DR4; DR5; Apoptosis; Six1; GALNT14; XIAP; Mapatumumab; Resistance; Cancer
Modulation of osteoblast gap junction connectivity by serum, TNFα, and TRAIL
Keywords: DR4; CX43; Osteoblast; Osteocyte; Gap junction;
TRAIL Death Receptor-4 Expression Positively Correlates With the Tumor Grade in Breast Cancer Patients With Invasive Ductal Carcinoma
Keywords: Breast cancer; TRAIL; DR4; Apoptosis;
Functional expression of TRAIL receptors TRAIL-R1 and TRAIL-R2 in esophageal adenocarcinoma
Keywords: TRAIL receptors; DR4; DR5; Apoptosis; Immunohistochemistry; Adenocarcinoma; Esophagus;
An LXXLL motif in nuclear receptor corepressor mediates ligand-induced repression of the thyroid stimulating hormone-β gene
Keywords: ACTR; acetyltransferase; CBP; CREB-binding protein; CoRNR motif; corepressor-nuclear receptor-binding motif; DES; Drosophila expression system; DR4; direct repeat with a four-nucleotide spacing; ER; estrogen receptor; HDAC; histone deacetylase; HSV; human
Death receptors and ligands in cervical carcinogenesis: an immunohistochemical study
Keywords: Cervical cancer; CIN; Fas; FasL; DR4; DR5; TRAIL; Apoptosis; Proliferation; Immunohistochemistry;
Transcriptional regulatory networks in lipid metabolism control ABCA1 expression
Keywords: A2AR; adenosine A2A receptor; ABC; ATP-binding cassette; ACAT1; acyl-CoA:cholesterol acyltransferase 1; AP; adapter protein; apo; apolipoprotein; ARL7; ADR-ribosylation factor-like 7; ARNT; arylhydrocarbon receptor nuclear translocator; ATRA; all-trans re