Keywords: Antibody-drug-conjugate; Hydrophobic interaction chromatography; Reversed phase chromatography; Size exclusion chromatography; Multi-dimensional separation; Drug to antibody ratio;
مقالات ISI (ترجمه نشده)
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Keywords: ADCs; antibody-drug-conjugates; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; B-NHL; B-cell non-Hodgkin's lymphoma; ccRCC; clear cell renal cell carcinoma; DLBCL; diffuse large B-cell lymphoma; DAR; drug to antibody ratio; ECM; extra cellu
Drug-to-antibody determination for an antibody-drug-conjugate utilizing cathepsin B digestion coupled with reversed-phase high-pressure liquid chromatography analysis
Keywords: Cathepsin B; DAR; Drug to antibody ratio; ADC; Antibody drug conjugate;
A new anti-human Fc method to capture and analyze ADCs for characterization of drug distribution and the drug-to-antibody ratio in serum from pre-clinical species
Keywords: ADC; antibody drug conjugates; DAR; drug to antibody ratio; Fc; fragment crystallizable HC heavy chain; IgG; immunoglobulin G; LC; light chain; LC-MS; liquid chromatography-mass spectrometry; mAb; monoclonal antibody; RT; room temperature; ELISA; enzy
Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography
Keywords: Hydrophobic interaction chromatography; Monoclonal antibody; Antibody-drug conjugate; Organic modifier; Denaturation; Drug to antibody ratio
Structural characterization of antibody drug conjugate by a combination of intact, middle-up and bottom-up techniques using sheathless capillary electrophoresis – Tandem mass spectrometry as nanoESI infusion platform and separation method
Keywords: Sheathless capillary electrophoresis-mass spectrometry; Antibody-drug conjugate; vcMMAE-ADC; Drug to antibody ratio; Drug-loaded peptides