Keywords: Ds، دو رشته; BPEV, Bell pepper endornavirus; SNV, single nucleotide variation; ds, double-stranded; NGS, next-generation sequencing; SRA, Sequence Read Archive; NCBI, National Center for Biotechnology Information; VCF, Variant Call Format; IGV, Integrative Genomics Vi
مقالات ISI Ds، دو رشته (ترجمه نشده)
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Keywords: Ds، دو رشته; ALKBH, AlkB homolog; 1-meA, 1-methyladenine; 3-meC, 3-methylcytosine; 2OG, 2-oxoglutarate; FTO, fat mass and obesity-associated; ss, single-stranded; ds, double-stranded; CRPC, castrate resistant prostate cancer; NACLC, non-small cell lung cancer; LC-MS/M
Surface complex of ZnTMPyP4 metalloporphyrin with double-stranded Poly(A)-Poly(U)
Keywords: Ds، دو رشته; Zn(X)TMPyP4; Poly(A)-Poly(U); CooperativityTMPyP4, 5,10,15,20-tetrakis (N-methylpyridinium-4-yl)porphyrin; Poly(A)-Poly(U), Polyadenylnic-polyurridylic acid; mPAU, Monomeric unit of Poly(A)-Poly(U); Kin, Intrinsic binding constant; ds, Double-stranded; AM
The mitochondrial genome of a Texas outbreak strain of the cattle tick, Rhipicephalus (Boophilus) microplus, derived from whole genome sequencing Pacific Biosciences and Illumina reads
Keywords: Ds، دو رشته; A, adenine; bp, base pairs; C, cytosine; DNA, deoxyribonucleic acid; ds, double-stranded; G, guanine; kb, kilobase; min, minutes; mt, mitochondria; nt, nucleotide; PCR, polymerase chain reaction; RNA, ribonucleic acid; T, thymineCattle tick; Mitochondrial
Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells
Keywords: Ds، دو رشته; ER, endoplasmic reticulum; PKR, protein kinase, RNA-activated; ds, double-stranded; CHOP, C/EBP homologous protein; ALS, amyotrophic lateral sclerosis; UPR, unfolded protein response; IFN, interferon; IRES, internal ribosome entry site; EV, empty vector;
Control of RecBCD Enzyme Activity by DNA Binding- and Chi Hotspot-Dependent Conformational Changes
Keywords: Ds، دو رشته; ds, double-stranded; ss, single-stranded; Bpa, p-benzoyl-l-phenylalanine; SAXS, small-angle X-ray scattering; EDTA, ethylenediaminetetraacetic acid; bp, base-pair; kDa, kilodalton; PBS, phosphate-buffered saline; TCEP, tris(2-carboxyethyl)phosphinehelicas
Detection of DNA hybridization by field-effect DNA-based biosensors: mechanisms of signal generation and open questions
Keywords: Ds، دو رشته; FED, field-effect device; EISOI, electrolyte-insulator–semiconductor silicon-on-insulator structure; GNP, gold nano-particle; ss, single-stranded; ds, double-stranded; bp, base pair; ES, electrostatic; PB, Poisson–Boltzmann; [salt], salt concentrationDNA
Monocyte-derived dendritic cells enhance cell proliferation and porcine circovirus type 2 replication in concanavalin A-stimulated swine peripheral blood lymphocytes in vitro
Keywords: Ds، دو رشته; ANOVA, analysis of variance; APCs, antigen presenting cells; CFSE, 5-(and 6)-carboxyfluorescein diacetate succinimidyl ester; Con A, concanavalin A; DCs, dendritic cells; DMEM, Dulbecco modified Eagle medium; Ds, double-stranded; DPI, days post-inoculatio
Nuclear Factor-κB: Central Regulator in Ocular Surface Inflammation and Diseases
Keywords: Ds، دو رشته; angiogenesis; apoptosis; inflammation; NF-κB; signal transduction; transcription factors; wound healingAGE, Advanced glycation end products; CCL, Chemokine (C-C motif) ligand; COX, Cyclo-oxygenase; ds, Double-stranded; EGCG, Epigallocatechin gallate; ERK,
Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus
Keywords: Ds، دو رشته; ds, double-stranded; CSF, cerebrospinal fluid; GCV, ganciclovir; HCMV, human cytomegalovirus; MSCSA, mass spectrometry-based comparative sequence analysis; SCT, stem cell transplantation; SNP, single nucleotide polymorphism; vGCV, valganciclovirHuman cyto
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
Keywords: Ds، دو رشته; DNA-PK, DNA-dependent protein kinase; DNA-PKcs, DNA-PK catalytic subunit; ds, double-stranded; DSB, DNA double strand break; IR, ionizing radiation; NHEJ, non-homologous end joining; ss, single-stranded; SAXS, small angle X-ray scattering; XLF, XRCC4 like
Identification and functions of pattern-recognition receptors
Keywords: Ds، دو رشته; Pattern-recognition receptor; Toll-like receptor; RIG-I–like receptor; Nod-like receptor; C-type lectin receptor; systems biologyCARD domain, Caspase recruitment domain; CLR, C-type lectin receptor; DC, Dendritic cell; ds, Double-stranded; MyD88, Myeloid
Alternating 2′-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist
Keywords: Ds، دو رشته; Dendritic cells; Innate immunity; 2′-O-ribose methylation; siRNA; Toll-like receptorβ2m, beta-2-microglobulin; ds, double-stranded; eGFP, enhanced green fluorescence protein; siRNA, small interfering RNA; ss, single-stranded; TLRs, Toll-like receptors
Coupling Translocation with Nucleic Acid Unwinding by NS3 Helicase
Keywords: Ds، دو رشته; molecular motor; helicase; DNA/RNA unwinding; diffusion; stochastic simulationNS3, nonstructural protein 3; ss, single-stranded; ds, double-stranded; SF, superfamily; HCV, hepatitis C virus
Human Dicer C-terminus functions as a 5-lipoxygenase binding domain
Keywords: Ds، دو رشته; AD, activating domain; Ade, adenine; a.a., amino acids; ATP, adenosine triphosphate; BD, binding domain; C-term, C-terminal domain; ds, double-stranded; dsRBD, dsRNA binding domain; DTT, dithiothreitol; GSH, glutathione; GST, glutathione S-transferase; Hi
Matrix protein mediated shutdown of host cell metabolism limits vesicular stomatitis virus-induced interferon-alpha responses to plasmacytoid dendritic cells
Keywords: Ds، دو رشته; Dendritic cells; Interferons; Matrix protein; Viral escape; VSVBM, bone marrow; ds, double-stranded; IFN, interferon; LCMV, lymphocytic choriomeningitis virus; M, matrix; mda-5, melanoma differentiation-associated gene-5; mDC, myeloid dendritic cell(s); M
Effects of trichostatin A on neuronal mu-opioid receptor gene expression
Keywords: Ds، دو رشته; MOR, mu-opioid receptor; PCBP, poly C binding protein 1; ds, double-stranded; ss, single-stranded; TSA, trichostatin A; HDAC, histone deacetylase; HAT, histone acetyltransferase; CNS, central nervous system; ChIP, chromatin immunoprecipitation; Act D, act
Fluorescence-based detection of short DNA sequences under non-denaturing conditions
Keywords: Ds، دو رشته; PNA, peptide nucleic acid; bis-PNA or PNA openers, two PNA oligomers connected by a flexible linker; RCA, rolling-circle amplification; MB, molecular beacon; ds, double-stranded; ss, single-stranded; HTLV-1, human T-lymphotropic virus type 1; EBV, Epstein
The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities
Keywords: Ds، دو رشته; AdV, adenovirus; ASFV, African swine fever virus; CARD, caspase recruitment domain; CMV, cytomegalovirus; DC, dentritic cell; ds, double-stranded; EBV, Epstein-Barr virus; eIF, eukaryotic initiation factor; EMCV, encephalomyocarditis virus; FADD, Fas-asso
Bovine parainfluenza virus type 3 accessory proteins that suppress beta interferon production
Keywords: Ds، دو رشته; Bovine parainfluenza virus type 3; Sendai virus; C protein; V protein; Interferon; MDA5; RIG-IIFN, interferon; JAK, Janus tyrosine kinase; STAT, signal transducer and activator of transcription; ds, double-stranded; IRF3, interferon regulatory factor 3; S
Expression of PACT is regulated by Sp1 transcription factor
Keywords: Ds، دو رشته; IFN, interferon; ds, double-stranded; PKR, RNA-activated protein kinase; Sp1, Specificity protein 1; DRBD, dsRNA-binding domain; PP2A, protein phosphatase 2A; eIF2, eukaryotic initiation factor 2; EMSA, electrophoretic mobility shift analyses; dsRBM, dsRN
Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins
Keywords: Ds، دو رشته; bp, base pair(s); ds, double-stranded; kb, kilobase(s); miRNA, microRNA; RNA, ribonucleic acid; RNAi, RNA interference; Rnase, ribonuclease; siRNA, small interfering RNA.RNAi; Protein–protein interaction
The Argonaute protein TbAGO1 contributes to large and mini-chromosome segregation and is required for control of RIME retroposons and RHS pseudogene-associated transcripts
Keywords: Ds، دو رشته; ds, double-stranded; RNAi, RNA interference; siRNA, short interfering RNARNA interference; Retroposons; Pseudogenes; Argonaute; Mitosis; Trypanosome
Synergistic action of the Saccharomyces cerevisiae homologous recombination factors Rad54 and Rad51 in chromatin remodeling
Keywords: Ds، دو رشته; HR, homologous recombination; ss, single-stranded; ds, double-stranded; NTA, nitrilotriacetic acid; BSA, bovine serum albumin; GST, glutathione-S-transferaseRad51; Rad54; Chromatin remodeling; D-loop; Homologous recombination
An Asymmetric Structure of the Bacillus subtilis Replication Terminator Protein in Complex with DNA
Keywords: Ds، دو رشته; RTP, replication terminator protein; RMSD, root mean square deviation; ds, double-stranded; HSQC, heteronuclear single quantum coherencewinged-helix; DNA replication; replication terminator protein; polar fork arrest; cooperative binding
A RecA Mutant, RecA730, Suppresses the Recombination Deficiency of the RecBC1004D–χ* Interaction in Vitro and in Vivo
Keywords: Ds، دو رشته; ds, double-stranded; ss, single-strandedRecA; RecBCD; recombination hotspot; DNA repair; RecA-loading
The NMR Structure of the gpU Tail-terminator Protein from Bacteriophage Lambda: Identification of Sites Contributing to Mg(II)-mediated Oligomerization and Biological Function
Keywords: Ds، دو رشته; NOE, nuclear Overhauser effect; aa, amino acids; St-ORF, S. typhimurium open reading frame; HSQC, heteronuclear single quantum coherence; ds, double-stranded; PFU, plaque-forming unitsNMR spectroscopy; viral structural protein
Crystal Structure and Activity of Kunjin Virus NS3 Helicase; Protease and Helicase Domain Assembly in the Full Length NS3 Protein
Keywords: Ds، دو رشته; KUNV, Kunjin virus; WNV, West Nile virus; YFV, yellow fever virus; DENV, Dengue virus; HCV, hepatitis C virus; RTPase, 5′-terminal RNA triphosphatase activity; ss, single-stranded; ds, double-stranded; NS3FL, full length KUNV NS3 protein; SAXS, small angl
Specific Recognition of a DNA Immunogen by its Elicited Antibody
Keywords: Ds، دو رشته; ss, single-stranded; ds, double-stranded; mAb, monoclonal antibody; CDR, complementarity determining region; SLE, Systemic Lupus Erythematosus; HPV, human papillomavirus; E2c, C-terminal domain of E2 protein from HPVanti-DNA; structure; antibody; autoimmu
A Dual-nuclease Mechanism for DNA Break Processing by AddAB-type Helicase-nucleases
Keywords: Ds، دو رشته; ss, single-stranded; ds, double-stranded; ExoI, Exonuclease IDNA recombination; DNA repair; DNA helicase; RecBCD; AddAB
Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate
Keywords: Ds، دو رشته; ss, single-stranded; ds, double-stranded; r.m.s.d., root mean square deviationtopoisomerase III; structure; complexes; ssDNA
Dodecameric Structure and ATPase Activity of the Human TIP48/TIP49 Complex
Keywords: Ds، دو رشته; TIP, TBP/transcription activating interacting protein; IPTG, isopropyl-1-thio-β-D-galactopyranoside; PMSF, phenylmethylsulphonyl fluoride; BSA, bovine serum albumin; ss, single-stranded; ds, double-stranded; AAA+, ATPases associated with different cellula
Gene Expression Analysis in Blood Cells in Response to Unmodified and 2′-Modified siRNAs Reveals TLR-dependent and Independent Effects
Keywords: Ds، دو رشته; TLR, Toll-like receptor; PBMC, peripheral blood mononuclear cells; ss, single-stranded; ds, double-stranded; siRNA, small interfering RNA; RISC, RNA-induced silencing complex; IFN, interferon; TNF, tumor necrosis factor; IL, interleukin; PKR, dsRNA-depend
A set of recombineering plasmids for gram-negative bacteria
Keywords: Ds، دو رشته; bp, base pair(s); nt, nucleotide(s); PCR, polymerase chain reaction; ts, temperature-sensitive; ori, origin of replication; ds, double-stranded; ss, single-stranded; CmR, chloramphenicol resistant; ApR, ampicillin resistant; TcR, tetracycline resistant; c
Binding of TmHU to Single dsDNA as Observed by Optical Tweezers
Keywords: Ds، دو رشته; optical tweezers; single molecule study; protein–DNA interaction; Thermotoga maritima; histone-like proteinTmHU, histone-like protein from Thermotoga maritima; SA, streptavidin; ds, double-stranded
The p53-induced Wig-1 protein binds double-stranded RNAs with structural characteristics of siRNAs and miRNAs
Keywords: Ds، دو رشته; ds, double-stranded; dsRBP, double-stranded RNA binding protein; FL, full-length; GST, glutathione S-transferase; miRNA, micro RNA; NLS, nuclear localization signal; siRNA, small interfering RNA; ss, single-stranded; Tet, tetracyclineWig-1; p53; dsRNA; Zi
Three-dimensional structure and stoichiometry of Helmintosporium victoriae190S totivirus
Keywords: Ds، دو رشته; 3DR, three-dimensional reconstruction; CP, capsid protein; cryo-EM, cryo-electron microscopy; ds, double-stranded; ctf, contrast transfer function; Hv190SV, Helminthosporium victoriae 190S virus; RDRP, RNA-dependent RNA polymeraseHv190SV; Double-stranded
Rapid Kinetics of Protein–Nucleic Acid Interaction is a Major Component of HIV-1 Nucleocapsid Protein’s Nucleic Acid Chaperone Function
Keywords: Ds، دو رشته; NC, nucleocapsid protein; aa, amino acid; ss, single-stranded; ds, double-stranded; HIV-1, human immunodeficiency virus type-1; FIM, force-induced melting; WT, wild-typenucleocapsid protein; nucleic acid chaperone; single molecule DNA stretching; DNA melt
Mapping of the Auto-inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance
Keywords: Ds، دو رشته; ds, double-stranded; PKR, protein kinase; RBD, dsRNA binding domain; HSQC, heteronuclear single quantum coherence; KD, kinase domain; NOESY, nuclear Overhauser enhancement spectroscopy; PKR, dsRNA activated protein kinasePKR; NMR: kinase; elF2α; RNA-bindi
Characterization of the Reactivity Determinants of a Novel Hairpin Substrate of Yeast RNase III
Keywords: Ds، دو رشته; ds, double-stranded; dsRBP, double-stranded RNA binding protein; BHB, bulge-helix-bulge; NUCD, nuclease domain; N-term, N-terminal; snR48, small nucleolar RNA 48dsRNA; dsRBD; ribonucleases; Rnt1p; tetraloop
The DNA Translocating ATPase of Bacteriophage T4 Packaging Motor
Keywords: Ds، دو رشته; aa, amino acid(s); ds, double-stranded; ELPs, empty large particles; ESPs, empty small particles; gp, gene product(s)phage T4; virus assembly; DNA translocation; terminase; DNA packaging
Transgene structures suggest that multiple mechanisms are involved in T-DNA integration in plants
Keywords: Ds، دو رشته; ds, double-stranded; DSB, double-strand break; DSBR, double-strand break repair; LB, T-DNA left border; NHEJ, non-homologous end-joining; RB, T-DNA right border; ss, single-stranded; SSA, single-strand annealing; SDSA, synthesis-dependent strand annealing
A Critical Coiled Coil Motif in the Small Terminase, gp16, from Bacteriophage T4: Insights into DNA Packaging Initiation and Assembly of Packaging Motor
Keywords: Ds، دو رشته; phage T4; virus assembly; DNA packaging; terminase; coiled coil motifgp, gene protein; CCM, coiled coil motif; ds, double-stranded; aa, amino acid(s)
Histidine Triad-like Motif of the Rotavirus NSP2 Octamer Mediates both RTPase and NTPase Activities
Keywords: Ds، دو رشته; ds, double-stranded; ss, single-stranded; DLP, double-layered particle; RdRP, RNA-dependent RNA polymerase; NTPase, nucleoside-triphosphate phosphohydrolase; PKCI, protein kinase C-interacting protein; HIT, histidine triad; RTPase, RNA triphosphatase; VLS
Transmission Electron Microscopy Reveals an Optimal HIV-1 Nucleocapsid Aggregation with Single-stranded Nucleic Acids and the Mature HIV-1 Nucleocapsid Protein
Keywords: Ds، دو رشته; HIV, human immunodeficiency virus; NCp, nucleocapsid protein; ss, single-stranded; ds, double-stranded; EM, electron microscopy; TEM, transmission electron microscopy; gp32, T4-encoded gene 32 protein; SSB, single-stranded binding; G4 DNA, parallel DNA qu
Sequential Release of Promoter Contacts during Transcription Initiation to Elongation Transition
Keywords: Ds، دو رشته; RNAP, RNA polymerase; 2-AP, 2-aminopurine; NT, non template; T, template; ds, double-stranded; IC, initiation conformation; EC, elongation conformation; TAMRA, tetramethylrhodaminepromoter clearance; stopped-flow kinetics; initial bubble collapse; transcr