The complexity of DNA double strand breaks is a critical factor enhancing end-resection
Keywords: DSBs, DNA double strand breaks; IR, ionizing radiation; HR, homologous recombination; LET, linear energy transfer; RPA, replication protein A; PIKK, phosphatidyl inositol 3′ kinase-related kinase; MEF, mouse embryonic fibroblast; MMEJ, micro homology-medi