Keywords: MPS, mononuclear phagocyte system; PEG, polyethylene glycol; DSPE, distearoylphosphatidylethanolamine; PEG-PE, PEG-phosphatidylethanolamine; PA, palmitic acid; Chol, cholesterol; PEG-Chol, PEGylated cholesterol; LUVs, large unilamellar vesicles; DOX, doxo