
Original ArticleMathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells
Keywords: فسفاتاز دو خاصیت; Hepatocellular carcinoma; Sorafenib; RAF-MEK-ERK cascade; Protein phosphatases; Mathematical modelling; DUSP; Dual-specificity phosphatases; EGFR; Epidermal Growth Factor Receptor; ERK1/2; Extracellular signal-Regulated Kinase 1/2; HCC; hepatocellular car