
Mechanism of influence of phosphorylation on serine 124 on a decrease of catalytic activity of human thymidylate synthase
Keywords: meTHF, N5,10-methylenetetrahydrofolate; TS, thymidylate synthase; hTS, human thymidylate synthase; RMSF, root-mean-square fluctuation; (phos)hTS, phosphorylated hTS; THF, tetrahydrofolate; ED, essential dynamics; MD, molecular dynamics; PDB, protein data