دانلود مقالات ISI درباره Eeache + ترجمه فارسی

در مورد استفاده از ثابت پایدار شدن آنزیم ثابت به عنوان اندازه گیری وابستگی مطلق مطلوب است

On the use of the experimentally determined enzyme inhibition constant as a measure of absolute binding affinity

Keywords: Dissociation constant; Inhibition constant; Affinity; Nonspecific binding; Nontarget site binding; Adsorption; Ki; enzyme inhibition constant; AChE; acetylcholinesterase; eeAChE; Electrophorus electricus AChE; ATCh; acetylthiocholine chloride; bis(7)-tacr

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

ترکیبات چندتایی که مویرهای ساختاری و عملکردی تاکرین و دونپزیل را دارند، برای درمان بالقوه بیماری آلزایمر

Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease

Keywords: ACh; acetylcholine; ChEs; cholinesterases; AChE; acetylcholinesterase; EeAChE; AChE from Electrophorus electricus; hAChE; human acetylcholinesterase; BuChE; butyrylcholinesterase; eqBuChE; BChE from equine serum; ChEI; ChE inhibitor; AChEI; AChE inhibitor

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

طراحی، سنتز و ارزیابی مشتقات جدید فنیل اسید-ال-آلکیلین به عنوان عوامل چند منظوره بالقوه برای درمان بیماری آلزایمر

Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: Alzheimer's disease; Ferulic acid-O-alkylamines derivatives; Multifunctional agents; Butyrylcholinesterase inhibition; Aβ aggregation; Antioxidant activity; Neuroprotective effects; BuChE; butyrylcholinesterase; AChE; acetylcholinesterase; Aβ; β-amyloi

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2017 سفارش ترجمه

Metal-involved theranostics: An emerging strategy for fighting Alzheimer's disease

Keywords: 3,4Apy; 3,4-diaminopyridine; 4Apy; 4-aminopyridine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; BBB; blood brain barrier; bpy; 2,2-bipyridine; BSA; bovine se

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AChEIs; acetylcholinesterase inhibitors; NMDA; N-methyl-d-aspartate; Aβ; β-amyloid; τ; tau protein; ACh; acetylcholine; MTDLs; multi-target-directed ligands; MAO-B; monoamine oxidase B; MAO-A; monoamine oxidase A; BuChE; buty

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

Keywords: Acetylcholinesterase inhibitor; Alzheimer's disease; Antarctic sponges; Discorhabdins; Molecular docking; Sponge metabolites; AChE; acetylcholinesterase; BChE; butyrylcholinesterase; eeAChE; electric eel acetylcholinesterase; ESI-MS; electrospray ionisati

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease

Keywords: Alzheimer's disease; Aurone Mannich base derivatives; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Multifunctional agents; AD; Alzheimer's disease; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; EeAChE; Electrophorus electricus

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: Alzheimer's disease; Scutellarein-O-acetamidoalkylbenzylamines; Multifunctional agents; Acetylcholinesterase inhibitors; Aβ aggregation inhibitors; Antioxidant agents; AD; Alzheimer's disease; AChE; acetylcholinesterase; ACh; acetylcholine; Aβ; β-amylo

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of novel ferulic acid-memoquin hybrids as potential multifunctional agents for the treatment of Alzheimer's disease

Keywords: AD; Alzheimer's disease; AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; Aβ; β-amyloid peptide; BBB; blood-brain barrier; ACh; acetylcholine; MTDL; multitarget-directed ligand; EeAChE; electric eel AChE; CAS; catalytic anionic site; PAS; p

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Keywords: Donepezil; Donepezil–indolyl hybrids; EeAChE; eqBuChE; hMAO A; hMAO B; Inhibitors; 3D-QSAR; Molecular modeling; ADMET

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors

Keywords: AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; AD; Alzheimer's disease; AChEI; acetylcholinesterase inhibitors; Aβ; β-amyloid; PAS; peripheral anionic site; eeAChE; Electrophorus electricus AChE; TcAChE; Torpedo californica AChE; hAChE; hum

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

Keywords: Indoles; Naphthyridines; Multipotent molecules; EeAChE; eqBuChE; MAO-A; MAO-B; Kinetic analysis; Inhibition mechanism; Molecular modeling; Amyloid β; Alzheimer's disease

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Rational polynomial equation helps to select among homeomorphic kinetic models for cholinesterase reaction mechanism

Keywords: AChE; acetylcholinesterase; BuChE; butyrylcholinesterase; ChE; cholinesterase; EeAChE; Electric eel acetylcholinesterase; ATCh; acetylthiocholine; DTNB; 5,5′-dithio-bis-nitro benzoic acid; pS; −log10 [S]; Enzyme kinetics; Cholinesterases; Mathematica

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه