Keywords: بازدارنده EGFR; Nanoparticle; Combination therapy; Sequential delivery; Triple negative breast cancer; EGFR inhibitor; Erlotinib; Doxorubicin;
مقالات ISI بازدارنده EGFR (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: بازدارنده EGFR; Crizotinib; Erlotinib; Phase I combination trial; MET inhibitor; EGFR inhibitor;
Keywords: بازدارنده EGFR; EGFR inhibitor; Meta-analysis; Metastatic colorectal cancer; VEGF inhibitor;
Keywords: بازدارنده EGFR; EGFR inhibitor; CE; HPLC–MS/MS; Natural product
Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo
Keywords: بازدارنده EGFR; PD153035; Tyrosine kinase inhibitor; Multidrug resistance; EGFR inhibitor; ABCG2;
Original ArticleTyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines
Keywords: بازدارنده EGFR; ABC transporter; ABCG2; EGFR inhibitor; Multidrug resistance; Tyrphostin RG14620; MDR; multidrug resistance; ABC; ATP-binding cassette; EGFR; epidermal growth factor receptor; FCS; fetal calf serum; CCK-8; Cell Counting Kit-8; IMDM; Iscove's Modified Dulb
Exploiting Synthetic Lethality and Network Biology to Overcome EGFR Inhibitor Resistance in Lung Cancer
Keywords: بازدارنده EGFR; SCLC; small cell lung cancer; NSCLC; non-small cell lung cancer; EGFR; epidermal growth factor receptor; EGFRi; EGFR inhibitor; PFS; progression-free survival; ORR; objective response rate; HER2; human epidermal growth factor receptor 2; EMT; epithelialâ
Novel quinoline-3-carboxamides (Part 2): Design, optimization and synthesis of quinoline based scaffold as EGFR inhibitors with potent anticancer activity
Keywords: بازدارنده EGFR; Quinoline-3-carboxamide; Optimization; EGFR inhibitor; Molecular modeling; % inhibition; MCF-7 cytotoxicity;
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase
Keywords: بازدارنده EGFR; Dihydrofuropyrimidine; Epidermal growth factor receptor; EGFR inhibitor; Non-covalent;
Pemetrexed With Platinum Combination as a Backbone for Targeted Therapy in Non-Small-Cell Lung Cancer
Keywords: بازدارنده EGFR; Angiogenesis inhibitor; EGFR inhibitor; Nonsquamous; Platinum-doublet chemotherapy;
Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor
Keywords: بازدارنده EGFR; EGFR inhibitor; Quinazoline and pyrido[2,3-d]pyrimidine derivatives; Antitumor; Molecular docking; Molecular dynamics simulation;
Panitumumab, Gemcitabine, and Carboplatin as Treatment for Women With Metastatic Triple-Negative Breast Cancer: A Sarah Cannon Research Institute Phase II Trial
Keywords: بازدارنده EGFR; Chemotherapy; EGFR inhibitor; Metastatic breast cancer; Panitumumab; Triple-negative breast cancer;
Design, synthesis and biological evaluation of 6-(nitroimidazole-1H-alkyloxyl)-4-anilinoquinazolines as efficient EGFR inhibitors exerting cytotoxic effects both under normoxia and hypoxia
Keywords: بازدارنده EGFR; EGFR inhibitor; 4-Anilinoquinazoline; Nitroimidazole; Normoxia; Hypoxia
EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse model
Keywords: بازدارنده EGFR; Epidermal growth factor receptor; Diabetic cardiomyopathy; Oxidative stress; ROS; EGFR inhibitor;
Lead compound bearing caffeic scaffold induces EGFR suppression in solid tumor cancer cells
Keywords: بازدارنده EGFR; CA, caffeic acid; CAPE, caffeic acid phenethyl ester; EGFR, epidermal growth factor receptor; RTK, receptor tyrosine kinase; TNBC, triple-negative breast cancerCaffeic acid derivatives; EGFR inhibitor; Triple-negative breast cancer; Non-small cell lung ca
Design, synthesis and biological activities of novel oxazolo[4,5-g]quinazolin-2(1H)-one derivatives as EGFR inhibitors
Keywords: بازدارنده EGFR; EGFR inhibitor; Oxazolo[4,5-g]quinazolin-2(1H)-one scaffold; Protein tyrosine kinases (PTK); Docking; SAR;
Synthesis and evaluation of 2-anilinopyrimidines bearing 3-aminopropamides as potential epidermal growth factor receptor inhibitors
Keywords: بازدارنده EGFR; EGFR inhibitor; Nitric oxide; Antiproliferative effects; 3-Aminopropamides; Acrylamide; Anilinopyrimidine
Liquid chromatography-tandem mass spectrometry assay for the EGFR inhibitor pelitinib in plasma
Keywords: بازدارنده EGFR; AUC; area under the plasma drug concentration-time curve; EDTA; ethylenediaminetetraacetic acid; HESI; heated electrospray ionization; IS; internal standard; kA; absorption rate constant; QC; quality control; SD; standard deviation; SRM; selected reacti
Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping
Keywords: بازدارنده EGFR; 2-Arylisoquinolin-1(2H)-ones; EGFR inhibitor; Antiproliferative activity; Synthesis; Scaffold hoping;
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor
Keywords: بازدارنده EGFR; EGFR inhibitor; EGFR T790M/L858R; Binding mode; Irreversible EGFR inhibitor;
VeriStrat® has a prognostic value for patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab in the first line: Pooled analysis of SAKK19/05 and NTR528
Keywords: بازدارنده EGFR; Biomarker; Chemotherapy; EGFR inhibitor; Lung cancer; Personalized medicine; Proteomics
Nitric oxide donating anilinopyrimidines: Synthesis and biological evaluation as EGFR inhibitors
Keywords: بازدارنده EGFR; Nitric oxide; EGFR inhibitor; Anilinopyrimidine; Antiproliferative activity; WZ4002
Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitors
Keywords: بازدارنده EGFR; EGFR inhibitor; Crown ether fused anilinoquinazoline; Synthesis;
Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC–EGFR dual inhibitors
Keywords: بازدارنده EGFR; N-Aryl salicylamides; HDAC inhibitor; EGFR inhibitor; Antiproliferative activity; Synthesis
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance
Keywords: بازدارنده EGFR; ABCG2; Multidrug resistance; Receptor tyrosine kinase; EGFR inhibitor; Cancer stem cell;
The risk of nail changes with epidermal growth factor receptor inhibitors: A systematic review of the literature and meta-analysis
Keywords: بازدارنده EGFR; cancer; cetuximab; EGFR inhibitor; erlotinib; lapatinib; nail toxicity; panitumumab; paronychiaAE, adverse event; CI, confidence interval; CTCAE, Common Terminology Criteria for Adverse Events (CTCAE); EGFR, epidermal growth factor receptor; EGFRIs, epide
Novel oxazolo[4,5-g]quinazolin-2(1H)-ones: Dual inhibitors of EGFR and Src protein tyrosine kinases
Keywords: بازدارنده EGFR; Protein tyrosine kinases (PTK); Anti-tumor agents; EGFR inhibitor; Src inhibitor; Oxazolo[4,5-g]quinazolin-2(1H)-one scaffoldNNLYOFSWWFKIMS-UHFFFAOYSA-N
Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolines
Keywords: بازدارنده EGFR; Combination strategy; Dithiocarbamic acid ester; 4-Anilinoquinazoline; EGFR inhibitor; Synthesis
Discovery of benzimidazole derivatives as novel multi-target EGFR, VEGFR-2 and PDGFR kinase inhibitors
Keywords: بازدارنده EGFR; Multi-target; EGFR inhibitor; VEGFR-2 inhibitor; PDGFR inhibitor; 2-Aryl benzimidazole; Anticancer
Three Years of Erlotinib in Routine Practice for Non-small Cell Lung Cancer in South East Scotland
Keywords: بازدارنده EGFR; EGFR inhibitor; erlotinib; mutation; non-small cell lung cancer; smoking status;
Phase II study of gefitinib in combination with paclitaxel (P) and carboplatin (C) as second-line therapy for ovarian, tubal or peritoneal adenocarcinoma (1839IL/0074)
Keywords: بازدارنده EGFR; Chemotherapy; EGFR inhibitor; Ovarian carcinoma; Relapse;
Radiosensitivity of prostate cancer cells is enhanced by EGFR inhibitor C225
Keywords: بازدارنده EGFR; EGFR inhibitor; Prostate cancer cells; Cell proliferation; Apoptosis
Receptor overexpression or inhibition alters cell surface dynamics of EGF–EGFR interaction: New insights from real-time single molecule analysis
Keywords: بازدارنده EGFR; TIRF; EGF; Dimerization; Cancer cells; Receptor density; Anti-EGFR drugs; AG1478; EGFR inhibitor
Epidermal growth factor competes with EGF receptor inhibitors to induce cell death in EGFR-overexpressing tumor cells
Keywords: بازدارنده EGFR; Epidermal growth factor (EGF); Epidermal growth factor receptor (EGFR); EGFR inhibitor; Apoptosis
Acute and fatal diarrhoea after erlotinib plus abdominal palliative hypofractionated radiotherapy in a metastatic non-small cell lung cancer patient: A case report
Keywords: بازدارنده EGFR; EGFR inhibitor; Targeted therapy; NSCLC; MSCC; Diarrhoea; Erlotinib; Hypofractionated radiotherapy; Combined modality
A phase I study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma
Keywords: بازدارنده EGFR; Ovarian cancer; Lapatinib; EGFR inhibitor; HER2 inhibitor
Epidermal growth factor receptor inhibitors enhance susceptibility to Fas-mediated apoptosis in oral squamous cell carcinoma cells
Keywords: بازدارنده EGFR; Squamous cell carcinoma; Fas; Apoptosis; EGFR inhibitor; c-FLIP
A Clinical Prognostic Index for Patients Treated with Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
Keywords: بازدارنده EGFR; Erlotinib; Non-small cell lung cancer; EGFR inhibitor; Prognostic
Priming with EGFR tyrosine kinase inhibitor and EGF sensitizes ovarian cancer cells to respond to chemotherapeutical drugs
Keywords: بازدارنده EGFR; EGF, epidermal growth factor; EGFR, epidermal growth factor receptor; ERK, extracellular signal-regulated kinase; PI3K, phosphoinositide-3 kinase; AKT, active human protein kinase; MAPK, mitogen-activated protein kinaseEGF; EGFR inhibitor; Down-regulation
Synthesis and structure–activity relationship of 4-(2-aryl-cyclopropylamino)-quinoline-3-carbonitriles as EGFR tyrosine kinase inhibitors
Keywords: بازدارنده EGFR; EGFR inhibitor; Quinoline-3-carbonitrile
In-Cell Western analysis of Helicobacter pylori-induced phosphorylation of extracellular-signal related kinase via the transactivation of the epidermal growth factor receptor
Keywords: بازدارنده EGFR; Helicobacter pylori; EGFR; ERK; Phosphorylation; EKB-569; EGFR inhibitor; ‘In-Cell Western’ assayEGFR, epidermal growth factor receptor; ERK, extracellular-signal related kinase; ICW, ‘In-Cell Western’; MAPK, mitogen-activated protein kinase; PAI, pathoge
Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib
Keywords: بازدارنده EGFR; Gastrin-releasing peptide; Akt kinase; Lung carcinoma; c-Src kinase; EGFR; Gefitinib; EGFR inhibitor
Pharmacokinetic profile of cetuximab (Erbituxâ¢) alone and in combination with irinotecan in patients with advanced EGFR-positive adenocarcinoma
Keywords: بازدارنده EGFR; EGFR inhibitor; C225; Colon cancer; Phase I;
An EGF receptor inhibitor induces RAR-β expression in breast and ovarian cancer cells
Keywords: بازدارنده EGFR; Cross-talk; EGFR inhibitor; ErbB receptors; RAR-β; Retinoid receptors;
Synthesis and antitumor evaluation of novel 5-substituted-4-hydroxy-8-nitroquinazolines as EGFR signaling-targeted inhibitors
Keywords: بازدارنده EGFR; EGFR inhibitor; Quinazolines; ErbB-2; Breast cancer; Cellular signaling