دانلود مقالات ISI درباره جهش EGFR + ترجمه فارسی

Compound EGFR Mutations and Response to EGFR Tyrosine Kinase Inhibitors

Keywords: جهش EGFR; Lung cancer; Non–small-cell lung cancer; Epidermal growth factor receptor; EGFR mutation; Erlotinib; Gefitinib; Tyrosine kinase inhibitor; L858R; L861Q; G719X; Exon 19 deletion compound; Exon 19 deletion double; Exon 19 deletion complex.

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

A Sequential Method of Epidermal Growth Factor Receptor Mutation Detection Reduces False Negatives: A New Case With Doublet Mutations of L833V and H835L in China

Keywords: جهش EGFR; EGFR mutation; False-negative; Workflow for mutation detection;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Detection and comparison of EGFR mutations in matched tumor tissues, cell blocks, pleural effusions, and sera from patients with NSCLC with malignant pleural effusion, by PNA clamping and direct sequencing

Keywords: جهش EGFR; Peptide nucleic acid-mediated real-time PCR clamping; Direct sequencing; Malignant pleural effusion; Lung cancer; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolic and metastatic characteristics of ALK-rearranged lung adenocarcinoma on FDG PET/CT

Keywords: جهش EGFR; FDG PET/CT; Metabolism; ALK rearrangement; EGFR mutation; Lung cancer; SUV

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

EGFR-tyrosine kinase inhibitor treatment beyond progression in long-term Caucasian responders to erlotinib in advanced non-small cell lung cancer: A case-control study of overall survival

Keywords: جهش EGFR; AC; adenocarcinoma; BSC; best supportive care; CI; 95% confidence interval; EGFR; epidermal growth factor receptor; EGFRM; EGFR mutation; HR; hazard ratio; n.s.; not significant; NSCLC; non-small cell lung cancer; OS; overall survival; PFS; progression-fr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Tumor Burden is Predictive of Survival in Patients With Non-Small-Cell Lung Cancer and With Activating Epidermal Growth Factor Receptor Mutations Who Receive Gefitinib

Keywords: جهش EGFR; Clinical predictors; EGFR mutation; Gefitinib; Non-small-cell lung cancer; Tumor burden;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

How Sensitive Are Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors for Squamous Cell Carcinoma of the Lung Harboring EGFR Gene–Sensitive Mutations?

Keywords: جهش EGFR; Squamous cell carcinoma; EGFR mutation; Epidermal growth factor–receptor tyrosine kinase inhibitor.

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Continued treatment with gefitinib beyond progressive disease benefits patients with activating EGFR mutations

Keywords: جهش EGFR; Beyond PD; EGFR mutation; Gefitinib; Non-small cell lung cancer; Secondary resistance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Biologic Approaches to Drug Selection and Targeted Therapy

Keywords: جهش EGFR; Targeted therapy; Individualized medicine; EGFR mutation; ALK translocation; Tumor genome sequencing;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Tumor response and health-related quality of life in clinically selected patients from Asia with advanced non-small-cell lung cancer treated with first-line gefitinib: Post hoc analyses from the IPASS study

Keywords: جهش EGFR; NSCLC; Gefitinib; EGFR-TKI; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Response to First-Line Chemotherapy in Patients With Non–Small-Cell Lung Cancer According to Epidermal Growth Factor Receptor and K-RAS Mutation Status

Keywords: جهش EGFR; Chemotherapy; EGFR mutation; K-RAS mutation; NSCLC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Immunostaining with EGFR mutation–specific antibodies: a reliable screening method for lung adenocarcinomas harboring EGFR mutation in biopsy and resection samples

Keywords: جهش EGFR; Lung adenocarcinoma; Biopsy; Resection; EGFR mutation; Immunohistochemistry; Mutation-specific monoclonal antibody

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Monitoring reversible and irreversible EGFR inhibition with erlotinib and afatinib in a patient with EGFR-mutated non-small cell lung cancer (NSCLC) using sequential [18F]fluorothymidine (FLT-)PET

Keywords: جهش EGFR; EGFR mutation; Treatment monitoring; FLT-PET; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Differential sensitivities to tyrosine kinase inhibitors in NSCLC harboring EGFR mutation and ALK translocation

Keywords: جهش EGFR; Non-small cell lung cancer; EGFR mutation; ALK translocation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

EGFR mutation testing in non-small cell lung cancer (NSCLC)

Keywords: جهش EGFR; Adenocarcinoma of lung; EGFR mutation; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

Efficacy of epidermal growth factor receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 mutation

Keywords: جهش EGFR; Brain metastasis; EGFR mutation; EGFR TKI; Non-small cell lung cancer; Erlotinib; Gefitinib;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

NF-κB signaling is activated and confers resistance to apoptosis in three-dimensionally cultured EGFR-mutant lung adenocarcinoma cells

Keywords: جهش EGFR; Lung adenocarcinoma; EGFR mutation; Three-dimensional culture; NF-κB; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Detection and comparison of peptide nucleic acid-mediated real-time polymerase chain reaction clamping and direct gene sequencing for epidermal growth factor receptor mutations in patients with non-small cell lung cancer

Keywords: جهش EGFR; Peptide nucleic acids (PNAs); Direct gene sequencing; EGFR mutation; Non-small cell lung cancer

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

EGFR mutations as a predictive marker of cytotoxic chemotherapy

Keywords: جهش EGFR; EGFR mutation; Cytotoxic chemotherapy; Taxane; Gemcitabine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Small-Cell Lung Cancer in Never-Smokers: A Case Series With Information on Family History of Cancer and Environmental Tobacco Smoke

Keywords: جهش EGFR; EGFR mutation; Environmental tobacco smoke; Family history of cancer; K-ras mutation; Small-cell lung cancer;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

High epidermal growth factor receptor immunohistochemical expression in urothelial carcinoma of the bladder is not associated with EGFR mutations in exons 19 and 21: a study using formalin-fixed, paraffin-embedded archival tissues

Keywords: جهش EGFR; EGFR expression; EGFR mutation; Exon 19 deletion; Exon 21 L858R substitution; Urothelial carcinoma

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients

Keywords: جهش EGFR; MET; Lung cancer; EGFR mutation; FISH; BAC; Prognosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Prospective Study of Gefitinib Readministration After Chemotherapy in Patients With Advanced Non–Small-Cell Lung Cancer Who Previously Responded to Gefitinib

Keywords: جهش EGFR; Chemotherapy; EGFR mutation; Epidermal growth factor receptor tyrosine kinase inhibitor; Gefitinib responder; Non–small-cell lung cancer; Recharrenge

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studies

Keywords: جهش EGFR; EGFR–TKIs; Icotinib; NSCLC; In vivo; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The anti-proliferative effect of heat shock protein 90 inhibitor, 17-DMAG, on non-small-cell lung cancers being resistant to EGFR tyrosine kinase inhibitor

Keywords: جهش EGFR; Hsp90; Hsp90 inhibitor; 17-DMAG; Gefitinib; EGFR mutation; EGFR-TKI; Acquired resistance

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Establishing an EGFR mutation screening service for non-small cell lung cancer – Sample quality criteria and candidate histological predictors

Keywords: جهش EGFR; EGFR mutation; Biopsy; Non-small cell lung cancer; Sample quality; Histological predictors; Mutation testing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

EML4-ALK Translocation Predicts Better Outcome in Lung Adenocarcinoma Patients with Wild-Type EGFR

Keywords: جهش EGFR; EML4-ALK; EGFR mutation; Lung cancer; Adenocarcinoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma

Keywords: جهش EGFR; Adenocarcinoma; EGFR mutation; Diagnosis; Cytology; Immunohistochemistry

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

EGFR–TKI resistant non-small cell lung cancer (NSCLC): New developments and implications for future treatment

Keywords: جهش EGFR; Afatinib; EGFR mutation; EGFR–TKI; MetMAb; Tivantinib; NSCLC; Secondary resistance

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Hsp90 Inhibition Overcomes HGF-Triggering Resistance to EGFR-TKIs in EGFR-Mutant Lung Cancer by Decreasing Client Protein Expression and Angiogenesis

Keywords: جهش EGFR; HGF; EGFR-TKI resistance; Hsp90; Lung cancer; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Conversion from the “oncogene addiction” to “drug addiction” by intensive inhibition of the EGFR and MET in lung cancer with activating EGFR mutation

Keywords: جهش EGFR; EGFR mutation; Acquired resistance; Tyrosine kinase inhibitors; Molecular target therapy; Irreversible EGFR inhibitor; PTEN;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

High Incidence of EGFR Mutations in Korean Men Smokers with No Intratumoral Heterogeneity of Lung Adenocarcinomas: Correlation with Histologic Subtypes, EGFR/TTF-1 Expressions, and Clinical Features

Keywords: جهش EGFR; EGFR mutation; Lung cancer; Histology; Adenocarcinoma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Potential anti-tumor effect of IFN-λ2 (IL-28A) against human lung cancer cells

Keywords: جهش EGFR; Type III interferon; IL-28A; Non-small cell lung cancer; EGFR mutation; Apoptosis; Bioluminescent imaging

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Frequency of EGFR and KRAS Mutations in Lung Adenocarcinomas in African Americans

Keywords: جهش EGFR; EGFR mutation; KRAS; African Americans; Racial differences

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Complete Pathologic Response in Lung Tumors in Two Patients with Metastatic Non-small Cell Lung Cancer Treated with Erlotinib

Keywords: جهش EGFR; NSCLC; EGFR mutation; Erlotinib; Complete response; Bone metastases

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Phase II Trial of Dasatinib for Patients with Acquired Resistance to Treatment with the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Erlotinib or Gefitinib

Keywords: جهش EGFR; Acquired resistance; Lung adenocarcinoma; EGFR mutation; Targeted therapies; SRC kinase

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Screening for EGFR mutations in lung cancer, a report from India

Keywords: جهش EGFR; Non-small cell lung cancer; Epidermal growth factor receptor; EGFR mutation; ARMS-PCR; Tyrosine kinase inhibitors;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Frequency and Type of Epidermal Growth Factor Receptor Mutations in African Americans with Non-small Cell Lung Cancer

Keywords: جهش EGFR; EGFR mutation; Race; African American; Lung cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Quelle est la meilleure séquence thérapeutique chez les patients ayant un CBNPC avec mutation activatrice de l'EGFR ?

Keywords: جهش EGFR; Cancer bronchique; Mutation EGFR; Inhibiteur tyrosine kinase; Première ligne; Non small cell lung cancer; EGFR mutation; Tyrosine kinase inhibitors; First-line treatment;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Low-Dose Gefitinib Treatment for Patients with Advanced Non-small Cell Lung Cancer Harboring Sensitive Epidermal Growth Factor Receptor Mutations

Keywords: جهش EGFR; Gefitinib; EGFR mutation; Low-dose; Post hoc analysis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Clinicopathologic Factors Affecting the Progression-Free Survival of Patients With Advanced Non–Small-Cell Lung Cancer After Gefitinib Therapy

Keywords: جهش EGFR; EGFR mutation; Elderly; Epidermal growth factor receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Duration of prior gefitinib treatment predicts survival potential in patients with lung adenocarcinoma receiving subsequent erlotinib

Keywords: جهش EGFR; Gefitinib; Erlotinib; EGFR mutation; Resistance to EGFR-TKIs; Time to progression of gefitinib

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating Epidermal Growth Factor Receptor mutation: Implications for clinical practice and open issues

Keywords: جهش EGFR; Gefitinib; Advanced NSCLC; First-line treatment; EGFR mutation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Gefitinib as First-line Treatment in Elderly Epidermal Growth Factor Receptor-mutated Patients With Advanced Lung Adenocarcinoma: Results of a Nagano Lung Cancer Research Group Study

Keywords: جهش EGFR; EGFR mutation; Elderly patients; First-line treatment; Gefitinib; Lung adenocarcinoma;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Detection of Epithelial Growth Factor Receptor Mutations in Cerebrospinal Fluid from Patients with Lung Adenocarcinoma Suspected of Neoplastic Meningitis

Keywords: جهش EGFR; EGFR mutation; Cerebrospinal fluid; Lung cancer; Neoplastic meningitis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Single-agent gefitinib with concurrent radiotherapy for locally advanced non-small cell lung cancer harboring mutations of the epidermal growth factor receptor

Keywords: جهش EGFR; Non-small cell lung cancer; Locally advanced; Gefitinib; Radiotherapy; EGFR mutation

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Bronchoscopic Microsampling is a Useful Complementary Diagnostic Tool for Detecting Lung Cancer

Keywords: جهش EGFR; bronchoscopic microsampling; lung cancer; epigenetics; epithelial lining fluid; EGFR mutation; EML4-ALK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

EGFR and KRAS mutations in metastatic lung adenocarcinomas

Keywords: جهش EGFR; EGFR mutation; KRAS mutation; Metastatic non–small cell lung cancer; Lung adenocarcinoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Impact on Disease-Free Survival of Adjuvant Erlotinib or Gefitinib in Patients with Resected Lung Adenocarcinomas that Harbor EGFR Mutations

Keywords: جهش EGFR; Adjuvant therapy; Erlotinib; Gefitinib; EGFR mutation; Lung adenocarinoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Good response to pemetrexed in patients of lung adenocarcinoma with epidermal growth factor receptor (EGFR) mutations

Keywords: جهش EGFR; EGFR; epidermal growth factor receptor; TKI; tyrosine kinase inhibitor; NSCLC; non-small cell lung cancer; MPE; malignant pleural effusion; CXR; chest radiography; CT; computed tomography; MRI; magnetic resonance imaging; del; deletion; ins; insertion; Pe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه