Keywords: colesterol libre; EHNA; fibrosis; HGNA; homeostasis; free cholesterol; NASH; fibrosis; NAFLD; homeostasis;
مقالات ISI (ترجمه نشده)
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Keywords: AD; Alzheimer disease; DPCPX; 8-cyclopentyl-1,3-dipropylxanthine; DMSO; dimethylsulfoxide; EHNA; erythro-9-(2-hydroxy-3-nonyl)-adenine hydrochloride; ZM 241385; 4-(2-[7-amino-2-{2-furyl}{1,2,4}triazolo-{2,3-a}{1,3,5}triazin-5-yl-amino]ethyl) phenol; Adeno
Keywords: cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; dnPDE2A; a catalytically-dead mutant of PDE2; EHNA; erythro-9-(2-hydroxy-3-nonyl)adenine; FBS; fetal bovine serum; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carbo
Keywords: AAH; adenine aminohydrolase; APRT; adenine phosphoribosyltransferase; HGPRT; hypoxanthine-guanine phosphoribosyltransferase; XPRT; xanthine phosphoribosyltransferase; AK; adenosine kinase; dCF; 2â²-deoxycoformycin; ADSS; adenylosuccinate synthetase; EHNA
Effect of inhibition of axonemal dynein ATPases on the regulation of flagellar and ciliary waveforms in Leishmania parasites
Keywords: Flagella; Motility; Leishmania; Ciliobrevin; EHNA; Vanadate;
CD39 and CD73 in the aortic valve-biochemical and immunohistochemical analysis in valve cell populations and its changes in valve mineralization
Keywords: ADP; adenosine diphosphate; AMP; adenosine monophosphate; ATP; adenosine triphosphate; BSA; bovine serum albumin; CAVD; calcific aortic valve disease; CD31 (PECAM-1); platelet endothelial cell adhesion molecule; CD39 (eNTPD1); ectonucleoside triphosphate
Modifications of flexible nonyl chain and nucleobase head group of (+)-erythro-9-(2â²s-hydroxy-3â²s-nonyl)adenine [(+)-EHNA] as adenosine deaminase inhibitors
Keywords: ADA; EHNA; Nonyl chain modification; Constrained analogues; Docking; Pharmacokinetics;
Deletion of CD73 in mice leads to aortic valve dysfunction
Keywords: ABTS; 2,2â²-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); ADA; adenosine deaminase; ADP; adenosine diphosphate; ALP; alkaline phosphatase; AMP; adenosine monophosphate; AOPCP; α,β-Methylene-ADP; AS; aortic stenosis; ATP; adenosine triphosphate; A
Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X1, P2X2, P2X3 channels, P2Y and A3 metabotropic receptors in neurotransmission
Keywords: ATP; Endogenous adenosine; Human enteric nervous system; Submucous plexus; Purinergic synaptic transmission; P2X channels; Inhibitory P2Y receptors; A3 inhibitory receptors; ARL67156; 6-N,N-diethyl-D-β,γ-dibromomethyleneATP; ATP; adenosine 5â²-triphosp
Phosphodiesterase 2 negatively regulates adenosine-induced transcription of the tyrosine hydroxylase gene in PC12 rat pheochromocytoma cells
Keywords: 5,6-DM-cBIMP; 5,6-dimethyl-1-beta-D-ribofuranosylbenzimidazole-3â²,5â²-cyclic monophosphate; Ado; adenosine; EHNA; erythro-9-(2-hydroxy-3-nonyl)adenine; IBMX; 3-isobutyl-1-methylxanthine; rANP; rat atrial natriuretic peptide; PDE2; phosphodiesterase 2;
Transport of c-MYC by Kinesin-1 for proteasomal degradation in the cytoplasm
Keywords: RBL; rose bengal lactone; EHNA; erythro-9-[3-(2-hydroxynonyl)] adenine; LMB; leptomycin B; KLC1; Kinesin Light Chain 1; DMSO; dimethyl sulfoxide; HMWS; high molecular-weight species; DAPI; 4â²,6-diamidino-2-phenylindole; c-MYC; Kinesin-1; Trafficking; Pr
A soluble phosphodiesterase in Leishmania donovani negatively regulates cAMP signaling by inhibiting protein kinase A through a two way process involving catalytic as well as non-catalytic sites
Keywords: L. donovani; Phosphodiesterase; Psudosubstrate residues; Phosphorylation; Protein kinase A; PDE; phosphodiesterase; DAPI; 4â²,6-diamidino-2â²-phenylindole dihydrochloride; LdPDEA; L. donovani cAMP phosphodiesterase A; LdPDED; L. donovani cAMP phosphodie
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: Evidence for a role of the adenosinergic system
Keywords: ANOVA; analysis of variance; AR; adenosine receptor; CPIP; chronic post-ischemic pain; CRPS-I; complex regional pain syndrome type I; DMSO; dimethylsulfoxide; DPCPX; 1,3-dipropyl-8-cyclopentylxanthine; EHNA; erythro-9-(2-hydroxy-3nonyl) adenine; IMP; inos
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: Hot shot drug delivery befor
Keywords: ATP; adenosine triphosphate; EHNA; erythro-9-[2-hydroxy-3-nonyl]adenine; es-ENT1; equilibrative-p-nitrobenzylthioinosine-sensitive type of the equilibrative nucleoside transport 1; HPLC; high-performance liquid chromatography; NBMPR; p-nitrobenzylthioin
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: Role of adenosine A1 receptor
Keywords: ATP; adenosine triphosphate; DPCPX; 8-cyclopentyl-1,3-dipropyl-xanthine; EHNA; erythro-9 (2-hydroxy-3-nonyl)-adenine; NBMPR; p-nitro-benzylthioinosine; SPT; 8-(p-sulfophenyl)theophyline;
Myocardial protection in beating heart cardiac surgery: I: Pre- or postconditioning with inhibition of es-ENT1 nucleoside transporter and adenosine deaminase attenuates post-MI reperfusion-mediated ventricular fibrillation and regional contractile dysfunc
Keywords: 23; 24; 30; 31; ATP; adenosine triphosphate; CABG; coronary artery bypass grafting; EHNA; erythro-9 (2-hydroxy-3-nonyl)-adenine; es-ENT1; p-nitrobenzylthioinosine-sensitive equilibrative nucleoside transporter 1; LAD; left anterior descending; MI; myocard
Caveolae compartmentalise β2-adrenoceptor signals by curtailing cAMP production and maintaining phosphatase activity in the sarcoplasmic reticulum of the adult ventricular myocyte
Keywords: AKAP; A kinase anchoring protein; ARVM; adult rat ventricular myocyte; β-AR; beta adrenoceptor; C3SD; caveolin-3 scaffolding domain; cAMP; cyclic adenosine 3â²-5â²-monophosphate; Cav-3; caveolin-3; CGP; CGP20712A; EHNA; erythro-9-(2-hydroxy-3-nonyl)ade
Pharmacological actions of the South African medicinal and functional food plant Sceletium tortuosum and its principal alkaloids
Keywords: 5-HT; 5-hydroxytryptamine; n; adenosine receptor; AT; angiotensin receptor; BZD; benzodiazepine; B2; bradykinin receptor; CGRP; calcitonin gene related peptide; CB; cannabinoid receptor; CCK; cholecystokinin; Dn; dopamine receptors; EHNA; erythro-9-(2-hyd
Purification and characterization of Plasmodium yoelii adenosine deaminase
Keywords: EHNA; erythro-9-(2-hydroxy-3-nonyl) adenine; pCMB; p-chloromercuribenzoate; NEM; N-ethylmaleimide; EDTA; ethylenediamine tetraacetic acid; GdmCl; guanidinium hydrochloride; DEPC; di-ethyl pyrocarbonate; Adenosine deaminase; Drug resistance; Inhibitor; Mal
Cellular NeuroscienceResearch PaperPurinergic modulation in the development of the rat uncrossed retinotectal pathway
Keywords: critical period; adenosine receptors; development; superior colliculus; cAMP; topographic order; EHNA; erythro-9(2-hydroxy-3-nonyl) adenine; HRP; horseradish peroxidase; NECA; 5â²-N-ethylcarboxamido-adenosine; PND; postnatal day; SC; superior colliculus;
Conformational change of adenosine deaminase during ligand-exchange in a crystal
Keywords: Adenosine deaminase; EHNA; X-ray crystal structure; Induced fitting; Conformational change
Tuning adenosine A1 and A2A receptors activation mediates l-citrulline-induced inhibition of [3H]-acetylcholine release depending on nerve stimulation pattern
Keywords: ACh; acetylcholine; ADA; adenosine deaminase; ADO; adenosine; AF-DX 116; 11-[2-1[(diethylamino)methyl-1-piperidinyl]-acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-one; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; BAY 41-22
TcrPDEA1, a cAMP-specific phosphodiesterase with atypical pharmacological properties from Trypanosoma cruzi
Keywords: PDE; phosphodiesterase; IBMX; 3-isobutyl-1-methylxanthine; EHNA; erythro-9-(2-Hydroxy-3-nonyl)-adenine hydrochloride; cAMP signaling; Chagas' disease; Kinetoplastids; Phosphodiesterase;
Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium
Keywords: Adenosine deaminase; Pentostatin; EHNA; Thyroid hormones; Atrium; Heart; Guinea pig
Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures
Keywords: AC; adenylyl cyclase; Bic; bicuculline; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; DIV; days in vitro; EHNA; erythro-9-(2-hydroxy-3-nonyl)-adenine; MK-801; dizocilpine hydrogen maleate; IFN; ifenprodil; TTX; tetrodotoxin;
The effect of acidosis on adenosine release from cultured rat forebrain neurons
Keywords: ACE; acetate; AN; adenine nucleotides; ADO; adenosine; BCECF-AM; 2â²,7â²-bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester; CNTs; concentrative nucleoside transporters; CNS; central nervous system; DIV; days in vitro; EIPA; 5-(N)-ethyl-N-i
Adenosine deaminase activity in the serum and malignant tumors of breast cancer: The assessment of isoenzyme ADA1 and ADA2 activities
Keywords: ADA; adenosine deaminase; EHNA; erytro-9-(2-hydroxy-3-nonyl) adenine; ADA1; adenosine deaminase isoform 1; ADA2; adenosine deaminase isoform 2; Adenosine deaminase; Isoenzyme; Breast cancer;
ADA2 isoform of adenosine deaminase from pleural fluid
Keywords: ADA1; adenosine deaminase isoenzyme 1; ADA2; adenosine deaminase isoenzyme 2; Ado; adenosine; 2â²-dAdo; 2â²-deoxyadenosine; C50; CM-Sephadex C50; EHNA; erithro-9-(2-hydroxy-3-nonyl)adenine; G200; Sephadex G200 superfine; 1-dAdo; 1-deazaadenosine; 3-dAdo
Merits of HPLC-based method over spectrophotometric method for assessing the kinetics and inhibition of mammalian adenosine deaminase
Keywords: Reverse-phase HPLC; Spectrophotometric-enzyme kinetics; Adenosine deaminase; Adenosine; Inosine; EHNA;
Activation of glutamate receptors promotes a calcium-dependent and transporter-mediated release of purines in cultured avian retinal cells: possible involvement of calcium/calmodulin-dependent protein kinase II
Keywords: AMPA; alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate; CAMK II; calcium/calmodulin-dependent protein kinase type II; CNQX; (6-cyano-7-nitroquinoxaline-2,3-dione); DNQX; 6,7-dinitroquinoxaline-2,3-dione; EHNA; erythro-9-(2-hydroxy-3-nonyl)adenine hydr