In vivo evaluation of urokinase-loaded hollow nanogels for sonothrombolysis on suture embolization-induced acute ischemic stroke rat model
Keywords: Hollow nanogel; Ultrasound responsive; Urokinase delivery; Thrombolysis; In vivo evaluation; SD; Sprague-Dawley; MCA; middle cerebral artery; MCAO; middle cerebral artery occlusion; UK; urokinase; nUK; uPA-loaded nanogels; US; ultrasound; UK+US; ultrasou