Scaffold hopping identifies 6,8-disubstituted purines as novel anaplastic lymphoma kinase inhibitors
Keywords: ALK; anaplastic lymphoma kinase; cMet; hepatocyte growth factor receptor; DIPEA; N,N-Diisopropylethylamine; DMF; N,N-Dimethylformamide; EML4; echinoderm microtubule-associated protein-like 4; FDA; food and drug administration; gk; gatekeeper; μW; micro w