Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: Synthesis, pharmacological evaluation and mechanistic studies
Keywords: Alpha4Beta2 nicotinic receptor; MDMA; Enantioselective binding; Receptor up-regulation; Molecular modelling; Stereoselective synthesis; AP; alternative pose; BP; best pose; CNS; central nervous system; DA; dopamine; MD; molecular dynamics; MDMA; N-3,4-met