Keywords: کوسن های آندوکاردی; BAV; bicuspid aortic valve; BPV; bicuspid pulmonary valve; ECM; extracellular matrix; ADAMTS5; a disintegrin-like and metalloprotease domain with thrombospondin type motifs; EMT; epithelial to mesenchymal transition; WT; wild type; OFT; outflow tract; αS