A novel antihypertension agent, sargachromenol D from marine brown algae, Sargassum siliquastrum, exerts dual action as an L-type Ca2+ channel blocker and endothelin A/B2 receptor antagonist
Keywords: Marine natural product; Isolation; Vasodilation; Severe hypertension; Endotheline-1; L-type Ca2+ channel blocker; Endothelin A/B2 receptor antagonist;