Keywords: گردش خون وارداتی; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t
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Keywords: گردش خون وارداتی; Budesonide; Formoterol; Pharmacokinetic modeling; Asthma; AIC; akaike information criterion; ANOVA; analysis of variance; BE; bioequivalence; BIC; bayesian information criterion; BMI; body mass index; BSV%; percent between subject variability; BUD; budeso
Keywords: گردش خون وارداتی; Microbiota; Iodothyronines metabolism; Levothyroxine; Enterohepatic circulation; Thyroxine malabsorption; Selenium;
Keywords: گردش خون وارداتی; Drug development; Enterohepatic circulation; Salt selection; Stability; Solid-state;
Keywords: گردش خون وارداتی; Bile acids; Nonalcoholic fatty liver disease (NAFLD); Nonalcoholic steatohepatitis (NASH); Farnesoid X receptor (FXR); Gut-liver crosstalk; Enterohepatic circulation;
Keywords: گردش خون وارداتی; albumin; mathematical model; pharmacokinetics; protein binding; organic anion-transporting polypeptide transporters; food effects; hepatic transport; nonlinear pharmacokinetics; clinical pharmacokinetics; ADME; BA; bioavailability; BCS; biopharmaceutica
Keywords: گردش خون وارداتی; physiologically based pharmacokinetic modeling; drug interactions; Monte Carlo; in vitro-in vivo correlations (IVIVC); nonlinear regression; biliary excretion; biliary recycling; hepatic metabolism; hepatic transport; AUC; area under the curve of concen
Keywords: گردش خون وارداتی; Thioacetamide; Metabolomics; Bile acids; Hepatotoxicity; Transporter; Enterohepatic circulation;
Keywords: گردش خون وارداتی; fluorine MRI; bile acid malabsorption; enterohepatic circulation; imaging methods; intestinal absorption; site-specific delivery; transporters; targeted drug delivery; bile acid transporters; biliary excretion;
Organs-on-a-chip: Current applications and consideration points for in vitro ADME-Tox studies
Keywords: گردش خون وارداتی; Cell-based assay; Organs-on-a-chip; ADME-Tox; Drug discovery; Safety assessment; Standardization; Inter-organ network; Enterohepatic circulation; Gut-liver axis;
N-(4-[18F]fluorobenzyl)cholylglycine, a novel tracer for PET of enterohepatic circulation of bile acids: Radiosynthesis and proof-of-concept studies in rats
Keywords: گردش خون وارداتی; Bile acids; Bile Salt Export Pump; Enterohepatic circulation; Fluorine-18 labelling; Metabolism; Positron emission tomography;
Effects of dietary soybean meal on the bile physiology in rainbow trout, Oncorhynchus mykiss
Keywords: گردش خون وارداتی; Bile acid; Soybean meal; Fishmeal; Enterohepatic circulation;
Irinotecan-induced bile acid malabsorption is associated with down-regulation of ileal Asbt (Slc10a2) in mice
Keywords: گردش خون وارداتی; CPT-11; irinotecan; TBAs; total bile acids; BAM; bile acid malabsorption; ASBT; apical Na+-dependent bile salt transporter; EHC; enterohepatic circulation; IS; internal standard; NDCA; nor-desoxycholic acid; d4-CDCA; d4-chenodeoxycholic; CA; cholic acid;
Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data
Keywords: گردش خون وارداتی; clinical trial simulations; drug interactions; pharmacokinetics; physiologically based pharmacokinetic modeling; organic anion-transporting polypeptide transporters; CYP enzymes; AUC; area under the blood concentration-time curve; AUCR; area under the b
The effects of Chuanxiong on the pharmacokinetics of warfarin in rats after biliary drainage
Keywords: گردش خون وارداتی; Warfarin; Chuanxiong; Pharmacokinetics; Enterohepatic circulation; LC-MS/MS; Biliary drainage
The Farnesoid X Receptor: Good for BAD
Keywords: گردش خون وارداتی; Bile Acid Diarrhea; Enterohepatic Circulation; FGF-19; Chloride Secretion; Epithelium; ASBT; apical sodium-linked bile acid transporter; BAD; bile acid diarrhea; C4; 7α-hydroxy-4-cholesten-3-one; CA; cholic acid; CDCA; chenodeoxycholic acid; DCA; deoxych
The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells
Keywords: گردش خون وارداتی; PFIC1; ATP8B1; SLC10A2; Enterohepatic circulation; Diarrhea;
Pharmacokinetic modeling of enterohepatic circulation of mycophenolic acid in renal transplant recipients
Keywords: گردش خون وارداتی; enterohepatic circulation; MRP2 polymorphism; mycophenolic acid; population pharmacokinetics; renal transplant;
Reduced system exposures of total rhein and baicalin after combinatory oral administration of rhein, baicalin and berberine to beagle dogs and rats
Keywords: گردش خون وارداتی; Rh; rhein; BG; baicalin; B; baicalein; Be; berberine; SHXXT; San-Huang-Xie-Xin-Tang; HLJDT; Huang-Lian-Jie-Du-Tang; PSP; phenolsulfonphthalein; HPLC; High performance liquid chromatography; Papp; apparent permeability coefficient; Rhein; Baicalin; Berberi
The role of the gallbladder in humans
Keywords: گردش خون وارداتی; Gallbladder; Absorption; Cholesterol; Bile acids; Enterohepatic circulation; Lipoproteins; Gallstones; Cholecystectomy; CancerVesícula; Absorción; Colesterol; Ácidos biliares; Circulación enterohepática; Lipoproteínas; Cálculos biliares; Colecistectomía;
Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats
Keywords: گردش خون وارداتی; Thienorphine; Glucuronide conjugate; Biliary excreation; Enterohepatic circulation;LC-MS/MS
Oral Coadministration of β-Glucuronidase to Increase Exposure of Extensively Glucuronidated Drugs that Undergo Enterohepatic Recirculation
Keywords: گردش خون وارداتی; β-glucuronidase; enterohepatic circulation; glucuronidation; site-specific delivery; intestinal metabolism; oral absorption; ADME; pharmacokinetics; intestinal absorption; bioavailability;
Defects in Gallbladder Emptying and Bile Acid Homeostasis in Mice With Cystic Fibrosis Transmembrane Conductance Regulator Deficiencies
Keywords: گردش خون وارداتی; Enterohepatic Circulation; Cholehepatic Shunt; Bicarbonate Secretion; Bile Acid Transporters; Asbt; apical sodium-dependent bile salt transporter; BA; bile acid; cAMP; adenosine 3â²,5â²-cyclic monophosphate; Cck; cholecystokinin; CF; cystic fibrosis; CF
The enterohepatic circulation of amanitin: Kinetics and therapeutical implications
Keywords: گردش خون وارداتی; Amanitin intoxication; Enterohepatic circulation; Biliary excretion
Human detoxification of perfluorinated compounds
Keywords: گردش خون وارداتی; Bile acid sequestrants; Cholestyramine; Detoxification; Enterohepatic circulation; Perfluorinated compounds; Public health; Saponin compounds; Sauna therapy; Toxicology; Zeolites
Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease
Keywords: گردش خون وارداتی; Bile acid; Carcinogenesis; Enterohepatic circulation; Farnesoid X Receptor; Inflammation;
Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism
Keywords: گردش خون وارداتی; ABC; ATP-binding cassette; ASBT; apical sodium-dependent bile acid transporter; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone-3-sulfate; ER; endoplasmic reticulum; Endo H; endoglycosidase H; FGF; fibroblast growth factor; FGFR; fibroblast gr
The potential influence of genetic variants in genes along bile acid and bile metabolic pathway on blood cholesterol levels in the population
Keywords: گردش خون وارداتی; Cholesterol catabolism; Bile acid synthesis; Enterohepatic circulation; Genetics;
Possibility of enterohepatic recycling of ketoprofen in dogs
Keywords: گردش خون وارداتی; Ketoprofen; Enterohepatic circulation; Pharmacokinetics; Absorption
Does Abnormal Bile Acid Metabolism Contribute to NEC?
Keywords: گردش خون وارداتی; necrotizing enterocolitis; bile acids; enterohepatic circulation
Hepatobiliary excretion and enterohepatic circulation of colchicine in rats
Keywords: گردش خون وارداتی; Colchicine; Cytochrome P450; Enterohepatic circulation; Hepatobiliary excretion; P-glycoprotein
Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake
Keywords: گردش خون وارداتی; ASBT/Asbt, apical sodium-dependent bile salt transporter; BSEP, Bile salt export pump; NTCP/Ntcp, Na-taurocholate-cotransporting polypeptide; OATP, Organic anion-transporting polypeptide; OST, Organic solute transporterASBT; Enterohepatic circulation; Ile
Inhibition of the intestinal absorption of bile acids using cationic derivatives: Mechanism and repercussions
Keywords: گردش خون وارداتی; ASBT; Enterohepatic circulation; Ileum; Intestine; Liver; Polyamine; TransportASBT, apical sodium-dependent bile acid transporter; BAPA, bile acid-polyamine derivative; BSEP, bile salt export pump; CDCA, chenodeoxycholic acid; GC, glycocholic acid; NTCP,
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
Keywords: گردش خون وارداتی; Cholestasis; Liver; Bilirubin; Enterohepatic circulation; Multidrug resistanceABC, ATP-binding cassette; Asbt, apical sodium-dependent bile salt transporter; BDL, bile-duct ligation; HC, hyocholate; HDC, hyodeoxycholate; Km, Michaelis constant; MRP, multi
LC/MS/MS quantitation assay for pharmacokinetics of naringenin and double peaks phenomenon in rats plasma
Keywords: گردش خون وارداتی; LC/MS/MS; Pharmacokinetics; Double peaks; Naringenin; Enterohepatic circulation
Novel non-systemic inhibitor of ileal apical Na+-dependent bile acid transporter reduces serum cholesterol levels in hamsters and monkeys
Keywords: گردش خون وارداتی; Apical sodium-dependent bile acid transporter; Enterohepatic circulation; Hypocholesterolemic agent; Monkey; Hamster; Cholesterol
Asymptotics and bioavailability in a 17-compartment pharmacokinetic model with enterohepatic circulation and remetabolization
Keywords: گردش خون وارداتی; Enterohepatic circulation; Remetabolization; Bioavailability; Transition and elimination probabilities; Efficiency of enterohepatic circulation; Identifiability
The impact of intestinal microflora on serum bilirubin levels
Keywords: گردش خون وارداتی; Antibiotic; Bilirubin; Bilirubin catabolism; Enterohepatic circulation; Hyperbilirubinemia; Intestinal microflora; Neonatal jaundice; Urobilinoids; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATB; antibiotic; B.; Bacteroides; C.; Clost
Absorption and enterohepatic circulation of baicalin in rats
Keywords: گردش خون وارداتی; Baicalin; Absorption; First pass glucuronidation; Enterohepatic circulation;