
Simulation of interindividual differences in inactivation of reactive para-benzoquinone imine metabolites of diclofenac by glutathione S-transferases in human liver cytosol
Keywords: CDNB, 1-chloro-2,4-dinitrobenzene; EPNP, 1,2-epoxy-3-(p-nitrophenoxy)propane; M5, 2′-glutathion-S-yl-4′-hydroxy-deschlorodiclofenac; M2, 3′-glutathion-S-yl-4-hydroxy-diclofenac; M1, 4-glutathion-S-yl-5-hydroxy-diclofenac; 4′-OH-DF, 4′-hydroxy-diclofenac;