
Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines
Keywords: ADME, absorption, distribution, metabolism, and excretion; CHO, Chinese hamster ovary; CNS, central nervous system; ER, efflux ratio; FLIPR, fluorescence imaging plate reader; HLM, human liver microsomes; MDCK, Madin–Darby Canine Kidney cell line; MDR-1,