Cell adaptation to activated FGFR3 includes Sprouty4 up regulation to inhibit the receptor-mediated ERKs activation from the endoplasmic reticulum
Keywords: FGFR3, fibroblast growth factor receptor 3; TDII, thanatophoric dysplasia type II; cDNA-RDA, cDNA representational difference analysis; ERK, extracellular regulated kinases; ER, endoplasmic reticulumFibroblast growth factor receptor 3; Activating mutation