Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AA-EQS, annual average environmental quality standard; AhR, aryl hydrocarbon receptor; BNF, beta-naphthoflavone; dm, dry mass; DMSO, dimethyl sulfoxide; EE2, 17α-ethinylestradiol; EQS, environmental quality standard; EROD, ethoxyresorufin O-deethylase; LO
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Sub-lethal effects and bioconcentration of the human pharmaceutical clotrimazole in rainbow trout (Oncorhynchus mykiss)
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; Biomarkers; Depuration half time; Hematology; HistopathologyBFCOD, 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase; CAT, Catalase; CF, Condition factor; CLO, clotrimazole; CYP450, cytochrome P450; EROD, ethoxyresorufin O-deethylase; GPx, Glutathione p
Does dexamethasone affect hepatic CYP450 system of fish? Semi-static in-vivo experiment on juvenile rainbow trout
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AhR, aryl hydrocarbon receptor; BFCOD, 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase; BQ, 7-benzyloxyquinoline; BQOD, 7-benzyloxyquinoline O-debenzylase; DEX, dexamethasone; EROD, ethoxyresorufin O-deethylase; CYP450, cytochrome P450; PNPH, p-nitrop
Characterization of chicken cytochrome P450 1A4 and 1A5: Inter-paralog comparisons of substrate preference and inhibitor selectivity
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AROD, alkoxyresorufin O-dealkylase; BROD, benzyloxyresorufin O-debenzylase; CPR, NADPH-cytochrome P450 reductase; CYP(s), cytochrome P450(s); DMSO, dimethyl sulfoxide; EROD, ethoxyresorufin O-deethylase; MROD, methoxyresorufin O-demethylase; PBO, piperony
Responses of conventional and molecular biomarkers in turbot Scophthalmus maximus exposed to heavy fuel oil no. 6 and styrene
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AHR, aryl hydrocarbon receptor; AOX, peroxisomal acyl-CoA oxidase; CYP1A1, cytochrome P4501A1; EF1-α, elongation factor 1 alpha; EPA, U.S. Environmental Protection Agency; EROD, ethoxyresorufin O-deethylase; LP, labilization period; MMC, melanomacrophage
Benzo(a)pyrene-induced mitochondrial dysfunction and cell death in p53-null Hep3B cells
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; BaP, benzo(a)pyrene; DCF-DA, 7′-dichlorofluorescein diacetate; DMEM, Dulbecco's modified eagle medium; EROD, ethoxyresorufin O-deethylase; JNK, c-Jun N-terminal kinase; DMSO, dimethyl sulfoxide; LD, lactic acid; MDA, malondialdehyde; MMP, mitochondrial me
Correlation of xenobiotic-metabolizing enzymes, oxidative stress and NFκB signaling with histological grade and menopausal status in patients with adenocarcinoma of the breast
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; HEL, anti-hexanoyl lysine; EROD, ethoxyresorufin O-deethylase; GST, glutathione S-transferase; 4-HNE, 4-hydroxynoneal; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; IκB, inhibitor of κB; IKKβ, Ikappa B kinase β; MROD, methoxyresorufin O-demethylase; NFκB, nuclear
Carotenoids as regulators for inter-species difference in cytochrome P450 1A expression and activity in ungulates and rats
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; CYP, cytochrome P450; EROD, ethoxyresorufin O-deethylase; PAHs, polycyclic aromatic hydrocarbons; Nap, naphthalene; Ace, acenaphthene; Fle, fluorene; Ant, anthracene; Phe, phenanthrene; Flu, fluoranthene; Pyr, pyrene; BaA, benzo[a]anthracene; Chr, chrysen
Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AF, 2-aminofluorene; CYP1, cytochrome P450 1; DMAB, 4-dimethylaminobenzaldehyde; EROD, ethoxyresorufin O-deethylase; NAT1, N-acetyltransferase 1; NHEK, normal human epidermal keratinocytes; PABA, para-aminobenzoic acid; PPD, para-phenylenediamineHaCaT; Ke
Sublethal effects of the organic antifoulant Mexel®432 on osmoregulation and xenobiotic detoxification in the flatfish Solea senegalensis
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AChE, acetylcholinesterase (EC 3.1.1.7); CAT, catalase (EC 1.11.1.6); CbE, carboxylesterase (EC 3.1.1.1); EROD, ethoxyresorufin O-deethylase; GR, glutathione reductase (EC 1.6.4.2); GPX, glutathione peroxidase (EC 1.11.1.9); GST, glutathione S-transferase
Gender-associated modulation of inducible CYP1A1 expression by andrographolide in mouse liver
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AhR, aryl hydrocarbon receptor; ARNT, AhR nuclear translocator; B6, C57BL/6; D2, DBA/2; EROD, ethoxyresorufin O-deethylase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; 3-MC, 3-methylcholanthrene; P450, cytochrome P450; PAH, polycyclic aromatic hydroc
Xenobiotic metabolism gene expression in the EpiDerm™ in vitro 3D human epidermis model compared to human skin
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; 3D, three-dimensional; 3-MC, 3-methylcholanthrene; AKR, 3α-hydroxysteroid dehydrogenase; ALDH, aldehyde dehydrogenase; CES, carboxylesterase; EROD, ethoxyresorufin O-deethylase; FTHBS, full thickness human buttock skin; GPX, glutathione peroxidase; GST, g
Expression and inducibility of CYP1A1, 1A2, 1B1 by β-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; CYP, cytochrome P450; βNF, beta-naphthoflavone; RIF, rifampicin; GAPDH, glyceraldehyde 6-phosphate dehydrogenase; EROD, ethoxyresorufin O-deethylase; MEROD, methoxyresorufin O-demethylase; EFCOD, 7-ethoxy 4-(trifluoromethyl)coumarin deethylase; BQD, benzy
Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; APND, aminopyrine N-demethylase; CAT, catalase; CYP, cytochrome P450; CYP-red, NADPH-(CYP)-c-reductase; ECOD, ethoxycoumarin O-deethylase; EROD, ethoxyresorufin O-deethylase; GPX, glutathione peroxidase; GR, glutathione reductase; GST, glutathione S-trans
Chemoprevention of rat mammary carcinogenesis by Azadirachta indica leaf fractions: Modulation of hormone status, xenobiotic-metabolizing enzymes, oxidative stress, cell proliferation and apoptosis
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; HEL, anti-hexanoyl lysine; CEE, crude ethanolic extract; CYP, cytochrome P450; DMBA, 7,12-dimethylbenz[a]anthracene; EAF, ethyl acetate fraction; ER, estrogen receptor; EROD, ethoxyresorufin O-deethylase; GPx, glutathione peroxidase; GR, glutathione reduc
High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; CYP, cytochrome P450; CP, cyclophilin A; ER, ethoxyresorufin; EROD, ethoxyresorufin O-deethylase; RT-PCR, reverse transcription-polymerase chain reactionKava; Piper methysticum; Cytochrome P450 1A1; mRNA expression; Real-time RT-PCR; Rat liver; Hepatotoxi
Perturbation of rat hepatic metabolising enzymes by folic acid supplementation
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; CYP, Cytochrome P450; CYP-red, NADPH-(CYP)-c-reductase; APND, Aminopyrine N-demethylase; pNPH, p-Nitrophenol hydroxylase; PROD, Pentoxyresorufin O-dealkylase; EROD, Ethoxyresorufin O-deethylase; MROD, Methoxyresorufin O-demethylase; ECOD, Ethoxycoumarin O
Evaluation of the safety and bioactivity of purified and semi-purified glucoraphanin
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; ER-M, erucin mercapturate; EROD, ethoxyresorufin O-deethylase; GE, glucoerucin; GRP, glucoraphanin; HPLC, high performance liquid chromatography; MTT, 3-(4,5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide; NQO1, NAD(P)H-quinone oxidoreductase 1; SF,
Effects of fibrates, anti-inflammatory drugs and antidepressants in the fish hepatoma cell line PLHC-1: Cytotoxicity and interactions with cytochrome P450 1A
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; ANF, α-naphthoflavone; B[a]P, benzo[a]pyrene; BNF, β-naphthoflavone; CYP1A, cytochrome P450 1A; DMSO, dimethylsulfoxide; EC50, concentration of drug required to reach 50% of the maximal effect; EE2, ethynylestradiol; EROD, ethoxyresorufin O-deethylase; GS
Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; BROD, benzyloxyresorufin O-debenzylase; CYP450, cytochrome P450; EROD, ethoxyresorufin O-deethylase; GCS, γ-glutamylcysteine-synthetase; GSH, glutathione; GST, glutathione-S-transferase; K/C, kahweol and cafestol; MGMT, O6-methylguanine-DNA methyltransfer
Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AhR, aryl hydrocarbon receptor; ARNT, AhR nuclear translocator; B[a]A, benz[a]anthracene; β-NF, β-naphthoflavone; DMSO, dimethylsulfoxide; DRE, Dioxin Responsive Element; EROD, ethoxyresorufin O-deethylase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase;
Effect of mercury, cadmium, nickel, chromium and zinc on kinetic properties of NADPH-cytochrome P450 reductase purified from leaping mullet (Liza saliens)
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; ε-ACA, ε-amino caproic acid; 2′,5′-ADP, adenosine 2′,5′-bisphosphate; DEAE, diethylaminoethyl; EROD, ethoxyresorufin O-deethylase; HEPES, N-2-hydroxyethylpiperazine-N-2,ethane sulfonic acid; NADPH, nicotinamide adenine dinucleotide phosphate reduced form;
Antimutagenic properties of a polyphenol-enriched extract derived from sesame-seed perisperm
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; GSH, reduced glutathione; GST, glutathione S-transferase; PM, polyphenolic mixture; SSP, sesame-seed perisperm; BaP, benzo[a]pyrene; EROD, ethoxyresorufin O-deethylase; DMSO, dimethyl sulfoxide; GM, glucose medium; LPO, lipid peroxidation; CDNB, 1-chloro-
Selective impairment of drug-metabolizing enzymes in pig liver during subchronic dietary exposure to aflatoxin B1
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; AFB1, aflatoxin B1; ALP, alkaline phosphatase; AST, aspartate transaminase; ALT, alanine transaminase; CDNB, 1-chloro-2,4-dinitrobenzene; EROD, ethoxyresorufin O-deethylase; GST, glutathione S-transferase; γ-GT, γ-glutamyl transpeptidase; H&E, haematoxyli
Differential inhibition of hepatic microsomal alkoxyresorufin O-dealkylation activities by tetrachlorobiphenyls
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; PCB, polychlorinated biphenyl; CYP, cytochrome P450; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; MC, 3-methylcholanthrene; EROD, ethoxyresorufin O-deethylase; MROD, methoxyresorufin O-demethylase; BROD, benzyloxyresorufin O-debenzylase; PCB 47, 2,2′,4,4′-t
Effect of various doses of deoxynivalenol on liver xenobiotic metabolizing enzymes in mice
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; BSA, bovine serum albumin; CDNB, 1-chloro-2,4-dinitro-benzene; DCNB, 1,2-dichloro-4-nitrobenzene; DON, deoxynivalenol; EROD, ethoxyresorufin O-deethylase; GST, glutathione S-transferase; HRP, horseradish peroxydase; Ig, immunoglobulin; MROD, methoxyresoru
The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cyto R, NADPH cytochrome c reductase; EMD, ethylmorphine N-demethylase; EROD, ethoxyresorufin O-deethylase; GGT, γ-glutamyltransferase; MROD, methoxyresorufin O-dea
Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in MCF10A breast epithelial cells
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; PhIP; Heterocyclic amines; Cooked food mutagens; DNA adducts; Human breast epithelial cells; CYP; P450; Breast carcinogenesisAh receptor, aryl hydrocarbon receptor; EROD, ethoxyresorufin O-deethylase; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine;
Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2)
Keywords: EROD، ethoxyresorufin O-دی اتیلاز; Coffee diterpenes; Cafestol; Kahweol; N-nitrosodimethylamine; PhIP; Metabolic enzymes; Antimutagenicity; Micronucleus; HepG2; AFB1, aflatoxin B1; B(a)P, benzo[a]pyrene; CÂ +Â K, cafestol and kahweol; CDNB, 1-chloro-2,4-dinitrobenzene; CYP, cytochrome P-45