Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways
Keywords: یوکاریوتی; HIF-1; hypoxia-inducible factor-1; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; MAPK; mitogen-activated protein kinase; VEGF; vascular endothelial growth factor; EPO; erythropoietin; Topo-I; topoisomerase-I; eIF4E; eukaryotic