Keywords: اضافی متناوب; Neurosteroid; NAS; GABAA; NMDA; Synaptic; Extrasynaptic; Clinical candidate;
مقالات ISI اضافی متناوب (ترجمه نشده)
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Keywords: اضافی متناوب; Allosteric receptor-receptor interactions; Oligomerization; Heteroreceptor complexes; Metabotropic glutamate receptor; Ionotropic glutamate receptor; Extrasynaptic; Basal ganglia;
Keywords: اضافی متناوب; ABA; activity-based anorexia; AN; anorexia nervosa; CON; control; EX; exercise; FR; food restriction; GABA; gamma-aminobutyric acid; GAD; glutamic acid decarboxylase; LTP; long-term potentiation; MWM; Morris water maze; Rm; membrane resistance; SR; stratu
Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion
Keywords: اضافی متناوب; GABAA; Extrasynaptic; Binge drinking; THIP; Females; Mouse; Alcohol; Delta; Tonic inhibition;
GABAergic regulation of the HPA and HPG axes and the impact of stress on reproductive function
Keywords: اضافی متناوب; Neurosteroids; Stress; GABAA receptors; KCC2; GnRH; Estrous; Puberty; LH; Allopregnanolone; THDOC; Tonic inhibition; Extrasynaptic; Gabrd;
A novel heterocyclic compound targeting the dopamine transporter improves performance in the radial arm maze and modulates dopamine receptors D1-D3
Keywords: اضافی متناوب; Hippocampus; Presynaptic; Extrasynaptic; Dopamine receptor; Radial arm maze; Dopamine reuptake inhibitor
Memantine selectively blocks extrasynaptic NMDA receptors in rat substantia nigra dopamine neurons
Keywords: اضافی متناوب; CNQX, 6-cyano-7-nitro-quinoxalone; EPSC, excitatory postsynaptic current; NMDA, N-methyl-d-aspartate; SNC, substantia nigra zona compacta; TTX, tetrodotoxinWhole-cell recording; Brain slice; MK-801; DQP-1105; Synaptic; Extrasynaptic
Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice
Keywords: اضافی متناوب; Huntington disease; NMDA receptor; GluN2B; Extrasynaptic; p38; pCREB; Calpain; Calcium signaling; Striatum; Memantine;
Repeated intermittent alcohol exposure during the third trimester-equivalent increases expression of the GABAA receptor δ subunit in cerebellar granule neurons and delays motor development in rats
Keywords: اضافی متناوب; Fetal; Cerebellum; GABA; Tonic current; Ethanol; Extrasynaptic;
Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure
Keywords: اضافی متناوب; Glutamate receptor; NMDA receptor; Pharmacology; Synapse; Extrasynaptic; Excitotoxicity; MK-801; Magnesium;
Activation of extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1 neurons
Keywords: اضافی متناوب; Extrasynaptic; NMDA receptor; Long-term depression; Theta burst; MK-801; Hippocampus;
Modulation of diazepam-insensitive GABAA receptors by micromolar concentrations of thyroxine and related compounds in vitro
Keywords: اضافی متناوب; 3,5-T2, 3′,5′-diiodothyronine; rT3, reverse T3; TETRAC, 3,5,3′,5′-tetraiodothyroacetic acid; T3, triiodothyronine; THIP, Gaboxadol or 4,5,6,7,-tetrahydroisoxazolo(5,4-c)pyridine-3olGABAA receptor; Thyroid hormone; Extrasynaptic; Diazepam insensitive; 3H-R
Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration
Keywords: اضافی متناوب; Neurosteroid; Lickometer; Alcohol; Extrasynaptic; GABAA receptors;
Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice
Keywords: اضافی متناوب; NMDA receptor; GluN2A; GluN2B; Huntington's disease; Neurodegeneration; Striatal medium spiny neuron; Excitotoxicity; Glutamate; Extrasynaptic; Corticostriatal; Coculture; pCREB; Microfluidic isolation chamber; Electrophysiology; YAC128; Striatum;
The wake-promoting transmitter histamine preferentially enhances alpha-4 subunit-containing GABAA receptors
Keywords: اضافی متناوب; Sleep; Wake; Extrasynaptic; Modulation
Downregulation of Kv4.2 channels mediated by NR2B-containing NMDA receptors in cultured hippocampal neurons
Keywords: اضافی متناوب; IA; synaptic; extrasynaptic; ischemia; epilepsy; calpainALLN, Ac-LLnL-CHO; AMPA, (±) α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrate; BAP, back-propagating action potential; BAPTA-AM, 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid t
Novel compounds selectively enhance δ subunit containing GABAA receptors and increase tonic currents in thalamus
Keywords: اضافی متناوب; GABAA receptor; Delta subunit; Allosteric modulator; Thalamus; Extrasynaptic;
Benzodiazepine modulation of GABAA receptor opening frequency depends on activation context: A patch clamp and simulation study
Keywords: اضافی متناوب; Mechanism; Ion channel; Synaptic; Extrasynaptic; Affinity
In developing hippocampal neurons, NR2B-containing N-methyl-d-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death
Keywords: اضافی متناوب; apoptosis; necrosis; extrasynaptic; neuroprotection; NR2A; mEPSC; miniature excitatory postsynaptic current; NMDA; N-methyl-d-aspartate; NMDAR; N-methyl-d-aspartate receptor; NR2A-NMDAR; NR2A-containing N-methyl-d-aspartate receptor; SGG; salt-glucoseâ
Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking
Keywords: اضافی متناوب; extrasynaptic; nonvesicular; glutamate; microdialysis; cystine-glutamate antiporter; reinstatement; ANOVA; analysis of variance; CPG; (S)-4-carboxyphenylglycine; system xcâ; cystine-glutamate antiporter; mGluR; metabotropic glutamate receptor;
GABAA receptors in the thalamus: α4 subunit expression and alcohol sensitivity
Keywords: اضافی متناوب; Alcohol; Alpha-4 subunit; GABAA receptors; Extrasynaptic; Tonic inhibition; Thalamus
Modulation of GABAA receptors in cerebellar granule neurons by ethanol: a review of genetic and electrophysiological studies
Keywords: اضافی متناوب; GABA; Ethanol; Extrasynaptic; Presynaptic; GranuleACSF, artificial cerebrospinal fluid; AA, Alko Alcohol; ANA, Alko Non-alcohol; AT, Alcohol Tolerant; ANT, Alcohol Non-Tolerant; CGN, cerebellar granule neuron; d,l-APV, d,l-2-amino-5-phosphonovaleric acid;
Glutamate and GABA receptors and transporters in the basal ganglia: What does their subsynaptic localization reveal about their function?
Keywords: اضافی متناوب; ionotropic receptor; metabotropic receptor; presynaptic; extrasynaptic; immunogold; electron microscopeEAAT, excitatory amino acid transporter; EM, electron microscopic; GP, globus pallidus; GPe, external segment of the globus pallidus; GPi, internal segm