Keywords: Fab، قطعه آنتی ژن اتصال; LC–MS, liquid chromatography–mass spectrometry; CHO, Chinese hamster ovary; Fc, crystalline fragment; Fab, antigen-binding fragment; mAbs, monoclonal antibodies; PTMs, posttranslational modifications; CQAs, critical quality attributes; Lys-C, endoproteina
مقالات ISI Fab، قطعه آنتی ژن اتصال (ترجمه نشده)
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Stable expression and purification of a functional processed Fab′ fragment from a single nascent polypeptide in CHO cells expressing the mCAT-1 retroviral receptor
Keywords: Fab، قطعه آنتی ژن اتصال; CHO cells, Chinese hamster ovary cells; CDS, coding sequence; Fab, antigen-binding fragment; Fab′, Fab with hinge region on the heavy chain; Fd′, truncated antibody heavy chain; FMDV, foot and mouth disease virus; mCAT-1, mouse cationic amino acid transpo
A large human domain antibody library combining heavy and light chain CDR3 diversity
Keywords: Fab، قطعه آنتی ژن اتصال; VH, heavy chain variable domain; VL, light chain variable domain; dAb, domain antibody; Fab, antigen-binding fragment; CDR, complementarity determining region; L3, light chain CDR3; H2, heavy chain CDR2; H3, heavy chain CDR3; FR, framework region; KL, kap
Downregulation of EGFR by a novel multivalent nanobody-liposome platform
Keywords: Fab، قطعه آنتی ژن اتصال; VHH, variable domain of the heavy chain of a heavy chain antibody; mAb, monoclonal antibody; EGFR, epidermal growth factor receptor; Fab, antigen-binding fragment; scFv, single chain variable fragment; TKI, tyrosine kinase inhibitor; PEG, polyethylene gly
Coevolution of Antibody Stability and Vκ CDR-L3 Canonical Structure
Keywords: Fab، قطعه آنتی ژن اتصال; mAB, monoclonal antibody; Fv, variable domains; Fab, antigen-binding fragment; VL, light chain variable; VH, heavy chain variable domain; CDR, complementarity-determining region; CDR-L1, CDR-L2 and CDR-L3, first, second and third hypervariable loop of VL,
Structure of the Complex between HER2 and an Antibody Paratope Formed by Side Chains from Tryptophan and Serine
Keywords: Fab، قطعه آنتی ژن اتصال; Fab, antigen-binding fragment; RTK, receptor tyrosine kinase; EGFR, epidermal growth factor receptor; ECD, extracellular domain; SAXS, small-angle X-ray scattering; CDR, complementarity-determining region; NSD, normalized spatial discrepancy; HRG, heregul
Adapter-Directed Display: A Modular Design for Shuttling Display on Phage Surfaces
Keywords: Fab، قطعه آنتی ژن اتصال; scFv, single-chain Fv; Fab, antigen-binding fragment; VEGF, vascular endothelial growth factor; IL-13, interleukin 13; PBS, phosphate-buffered saline; HRP, horseradish peroxidase; PEG/NaCl, polyethylene glycol/sodium chloride; ABTS, 2,2′-azino-bis(3-ethyl
Improvement of an Antibody Neutralizing the Anthrax Toxin by Simultaneous Mutagenesis of Its Six Hypervariable Loops
Keywords: Fab، قطعه آنتی ژن اتصال; Fab, antigen-binding fragment; LT, lethal toxin; PA, protective antigen; CDR, complementarity determining region; VH, heavy chain variable domain; VL, light chain variable domain; Kd, dissociation constant; IC50, 50% inhibitory concentration; koff, dissoc
The Intrinsic Contributions of Tyrosine, Serine, Glycine and Arginine to the Affinity and Specificity of Antibodies
Keywords: Fab، قطعه آنتی ژن اتصال; CDR, complementarity-determining region; CDR-Hn, heavy-chain CDR 1, 2 or 3 (where n = 1, 2, or 3); CDR-L3, light-chain CDR3; Fab, antigen-binding fragment; HER2, epidermal growth factor receptor 2; PBS, phosphate-buffered saline; VEGF, vascular endothelia
Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein
Keywords: Fab، قطعه آنتی ژن اتصال; Fab, antigen-binding fragment; Fmoc, fluorenylmethyloxycarbonyl; FACS, fluorescence-activated cell sorter; PDB, Protein Data BankHIV-1 neutralization; induced CCR5 affinity; macromolecular interface transplantation; molecular mimicry; scorpion-toxin scaff
The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies
Keywords: Fab، قطعه آنتی ژن اتصال; CH, constant domain of the heavy chain; CL, constant domain of the light chain; Fab, antigen-binding fragment; scFv, single chain antibody fragment; VH, variable domain of the heavy chain; VL, variable domain of the light chainRecombinant Fab; scFv; Scorp
On the influence of vector design on antibody phage display
Keywords: Fab، قطعه آنتی ژن اتصال; A600, absorbance at 600 nm; CFU, colony forming units; ELISA, enzyme-linked immunosorbent assay; Fab, antigen-binding fragment; g3p, gene III protein; lacZ, beta galactosidase gene; mAb, monoclonal antibody; SupE, mutant phenotype conferring read-through
Utilization of recombinant Fab fragments in a cTnI immunoassay conducted in spot wells
Keywords: Fab، قطعه آنتی ژن اتصال; a.a.r., amino acid residue; AMI, acute myocardial infarction; BITC, biotin isothiocyanate; cTn, cardiac troponin; CH1, first constant domain of the heavy chain; DELFIA, dissociation enhanced lanthanide fluoroimmunoassay; Fab, antigen-binding fragment; Fd,