Keywords: Monoclonal antibodies; Biosimilar; Fc-fusion protein; Antibody; Drug conjugate; Capillary gel electrophoresis; Capillary zone; Electrophoresis; Capillary isoelectric focusing; Mass spectrometry;
مقالات ISI (ترجمه نشده)
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A fully automated three-step protein purification procedure for up to five samples using the NGC chromatography system
Keywords: Automated protein purification; Multi-dimensional chromatography; Fc-fusion protein; Protein A; Size exclusion chromatography; NGC-Chromatography system;
Clonal variation in productivity and proteolytic clipping of an Fc-fusion protein in CHO cells: Proteomic analysis suggests a role for defective protein folding and the UPR
Keywords: Chinese hamster ovary (CHO) cells; Fc-fusion protein; Productivity; Label-free quantitative proteomics; Biopharmaceuticals;
Characterization and minimization of sialic acid degradation in an Fc-fusion protein-producing CHO cell bioprocess
Keywords: Chinese hamster ovary cells; Fc-fusion protein; Sialic acid; Sialidase; pH;
Ultrafiltration behavior of an Fc-fusion protein: Filtrate flux data and modeling
Keywords: Ultrafiltration; Fc-fusion protein; Concentration polarization; Intermolecular interactions; Viscosity;
Insights in understanding aggregate formation and dissociation in cation exchange chromatography for a structurally unstable Fc-fusion protein
Keywords: Cation-exchange chromatography; Fc-fusion protein; Aggregate formation; Aggregate dissociation; Structurally unstable proteins
Analysis and characterization of aggregation of a therapeutic Fc-fusion protein
Keywords: Fc-fusion protein; Free thiols; Protein aggregation; Protein stability; Partially frozen
Biochemical characterization of a new recombinant TNF receptor-hyFc fusion protein expressed in CHO cells
Keywords: TNF-α; TNF blocker; Fc-fusion protein; TNFR-hyFc; Hybrid Fc; N-Glycan
Application of Quality by Design to the characterization of the cell culture process of an Fc-Fusion protein
Keywords: Cell culture process; Characterization; Quality by Design (QbD); Design of Experiments (DoE); Design space; Fc-Fusion protein
Transport of human immunoglobulin G and Fc-fusion proteins to chicken egg yolk
Keywords: chicken; yolk transport; immunoglobulin G (IgG) subclass; Fc-fusion protein; transgenic chicken bioreactor
Pulmonary administration of therapeutic proteins using an immunoglobulin transport pathway
Keywords: FcRn; Transepithelial transport; Erythropoietin; Interferon alpha; Interferon beta; Follicle stimulating hormone; Aerosol; Fc-fusion protein; Neonatal Fc receptor; Lung