
Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport
Keywords: FcγR; Fc-gamma receptor; FcRn; neonatal Fc-receptor; FMAIT; fetomaternal alloimmune thrombocytopenia; HPA; human platelet antigens; IVIG; intravenous immunoglobulin; HuVEC; human umbilical vein endothelial cells; JAR; human choriocarcinoma cells; IgG; Ne