Interaction between fed gastric media (Ensure Plus®) and different hypromellose based caffeine controlled release tablets: Comparison and mechanistic study of caffeine release in fed and fasted media versus water using the USP dissolution apparatus 3
Keywords: dpm, dips per minute; FaSSGF, fasted state simulated gastric fluid; FaSSIF, fasted state simulated intestinal fluid; SCoF, simulated colonic fluid; FeSSIF, fed state simulated intestinal fluid; t63, time when 63.2% of drug has been released; b, dissolutio