Keywords: FH، عامل H; aHUS, atypical hemolytic uremic syndrome; AP, alternative complement pathway; ELISA, enzyme-linked immunosorbent assay; ESRD, end-stage renal disease; CKD, chronic kidney disease; FB, factor B; FH, factor H; FI, factor I; MODS, multiple organ dysfunction
مقالات ISI FH، عامل H (ترجمه نشده)
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C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend
Keywords: FH، عامل H; aHUS, atypical hemolytic uremic syndrome; C3b, activated complement factor 3; C4b, activated complement factor 4; C4BP, C4b-binding protein; CCP, complement control protein (domain); CRP, C-reactive protein; Gla, γ-carboxyglutamic acid; FH, factor H; FI,
Complement factor H modulates the activation of human neutrophil granulocytes and the generation of neutrophil extracellular traps
Keywords: FH، عامل H; CR3, complement receptor type 3 (CD11b/CD18); DHR, dihydrorhodamine; DIC, differential interference contrast; FH, factor H; Fn, fibronectin; HSA, human serum albumin; NET, neutrophil extracellular trap; PMA, phorbol 12-myristate 13-acetate; ROS, reactive
Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)
Keywords: FH، عامل H; aHUS, Atypical haemolytic uraemic syndrome; BDC, Blood donor controls; CR1, complement receptor type 1; CHO, Chinese hamster ovary; DAF, decay accelerating factor; FH, Factor H; FHR, Factor H related; FH aAb, FH autoantibodies; Kna, Knops blood group anti
Putting the structure into complement
Keywords: FH، عامل H; MAC, membrane attack complex; FH, factor H; FI, factor I; FD, factor D; FB, factor B; MBL, mannose binding lectin; MACPF, membrane attack complex/perforin domain; CDC, cholesterol dependent cytolysinComplement; Structure; Regulation; Protein complexes
Molecular characterization of two novel cases of complete complement inhibitor Factor I deficiency
Keywords: FH، عامل H; C3, third complement factor; C4BP, C4b-binding protein; CR1, complement receptor 1; FB, Factor B; FH, Factor H; FI, Factor I; FIMAC, Factor I membrane attack complex; JIA, juvenile idiopathic arthritis; LDLr, low density lipoprotein receptor; MCP, membran
The effect of electrostatics on factor H function and related pathologies
Keywords: FH، عامل H; FH, Factor H; C3, complement system protein C3; C3b, the b-fragment of C3; CCP, complement control protein; MG, macroglobulin (referring to the α2-MG family); FB, Factor B; Bb, the b-fragment of FB; FI, Factor I; GAG, glycosaminoglycan; SNP, single nucleo
Complement factor I in health and disease
Keywords: FH، عامل H; aHUS, atypical hemolytic uremic syndrome; C4BP, C4b-binding protein; CFI, complement factor I gene; CR1, complement receptor 1; DFP, diisopropylfluorophosphate; ESRD, end-stage renal disease; FH, Factor H; FI, Factor I; FIMAC, factor I membrane attack com
Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Keywords: FH، عامل H; AP, alternative complement pathway; FH, factor H; aHUS, atypical haemolytic uremic syndrome; FH19–20, domains 19 to 20 of FH; Q1139A, FH19–20 protein containing the Q1139A mutation; R1203A, FH19–20 protein containing the R1203A mutation; PBS, phosphate-bu
Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b
Keywords: FH، عامل H; C3, complement component 3; SCIN, staphylococcal complement inhibitor; fH, factor H; fI, factor I; RCSB, Research Collaboratory for Structural Bioinformatics; SPR, surface plasmon resonance; CVF, cobra venom factorcomplement; C3 convertase; immune evasion
Semi-Rigid Solution Structures of Heparin by Constrained X-ray Scattering Modelling: New Insight into Heparin–Protein Complexes
Keywords: FH، عامل H; IdoA, α-l-iduronic acid; VCP, vaccinia complement control protein; AUC, analytical ultracentrifugation; GlcNS, N-suphated glucosamine; PDB, Protein Data Bank; FH, factor H; MIP-1α, macrophage inflammatory protein 1α; SCR, short complement regulatorheparin
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation
Keywords: FH، عامل H; C4BP, C4b-binding protein; CCP, complement control protein; CRP, C-reactive protein; CHAD, chondroadherin; ECM, extracellular matrix; FH, factor H; FMOD, fibromodulin; KS, keratan sulfate; LPS, lipopolysaccharide; LRR, leucine-rich repeat (protein family)
Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system
Keywords: FH، عامل H; HRG, histidine-rich glycoprotein; IC, immune complex; IIC, insoluble immune complex; SIC, soluble immune complex; TCC, terminal complement complex; NHS, normal human serum; FH, factor H; C4BP, C4b-binding protein; KCP, Kaposi sarcoma-associated herpes vir
Multimeric Interactions between Complement Factor H and Its C3d Ligand Provide New Insight on Complement Regulation
Keywords: FH، عامل H; AUC, analytical ultracentrifugation; aHUS, atypical haemolytic uraemic syndrome; CR, complement receptor; FH, factor H; PBS, phosphate-buffered saline; RU, response unit; SCR, short complement regulator; SPR, surface plasmon resonancefactor H; C3d; X-ray
Electrostatic Interactions Contribute to the Folded-back Conformation of Wild Type Human Factor H
Keywords: FH، عامل H; FH, Factor H; SCR, short complement regulator; AMD, age-related macular degeneration; aHUS, atypical haemolytic uraemic syndrome; CR1 and CR2, complement receptor type 1 and type 2Factor H; short complement regulator; X-ray scattering; analytical ultracen
Structural basis and functional effects of the interaction between complement inhibitor C4b-binding protein and DNA
Keywords: FH، عامل H; C4BP, C4b-binding protein; FI, factor I; CCP, complement control protein (domain); MAC, membrane attack complex; MCP, membrane cofactor protein; DAF, decay-accelerating factor; CR1, complement receptor 1; FH, factor H; GAG, glycosaminoglycan; HSQC, hetero
Native, amyloid fibrils and β-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly
Keywords: FH، عامل H; C4BP, C4b-binding protein; CRP, C-reactive protein; FDC, follicular dendritic cell; FH, factor H; MAC, membrane attack complex; MBL, mannose-binding lectin; NHS, normal human serum; PrP, prion protein; PrPC, prion protein—cellular variant; PrPSc, prion pr
Implications of the Progressive Self-association of Wild-type Human Factor H for Complement Regulation and Disease
Keywords: FH، عامل H; FH, factor H; SCR, short complement regulator; RG, radius of gyration; AMD, age-related macular degeneration; aHUS, atypical haemolytic uraemic syndromefactor H; oligomerisation; X-ray scattering; analytical ultracentrifugation; age-related macular degene
The Regulatory SCR-1/5 and Cell Surface-binding SCR-16/20 Fragments of Factor H Reveal Partially Folded-back Solution Structures and Different Self-associative Properties
Keywords: FH، عامل H; FH, Factor H; SCR, short complement regulator; aHUS, atypical haemolytic uraemic syndromeFactor H; X-ray scattering; homology modelling; ultracentrifugation
Sphingomyelinases D induce direct association of C1q to the erythrocyte membrane causing complement mediated autologous haemolysis
Keywords: FH، عامل H; SMase D, sphingomyelinase D; AP, alternative pathway; CP, classical pathway; SAP, serum amyloid P; CRP, C-reactive protein; MBL, mannose binding lectin; C4bp, C4b-binding protein; fH, factor H; E, Erythrocyte; NHS, normal human serum; C8d-HS, C8-depleted
Effect of chronic ethanol consumption on the expression of complement components and acute-phase proteins in liver
Keywords: FH، عامل H; FB, complement factor B; C1qA, complement C1qA-chain; C1qB, complement C1qB-chain; FD, factor D (adipsin); P, properdin; C8α, C8, alpha-chain; C8β, C8, beta-chain; FH, factor H; FI, factor I; C4bp, C4b binding protein; CN, clusterin; VN, vitronectin; DAF,
A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation
Keywords: FH، عامل H; aHUS, atypical hemolytic uremic syndrome; C4BP, C4b-binding protein; CR1, complement receptor 1; FB, factor B; FH, factor H; FI, factor I; FIMAC, factor I membrane attack complex (domain); ESRD, end-stage renal disease; LDLr, low density lipoprotein recep
Pathogenic implications for autoantibodies against C-reactive protein and other acute phase proteins
Keywords: FH، عامل H; ANA, Antinuclear antibody; APR, Acute-phase reaction; CRP, C-reactive protein; FcγR, Fc gamma receptor; FH, Factor H; ICs, Immune complexes; IL, Interleukin; MBL, Mannose-binding lectin; mCRP, Monomeric CRP; OD, Optical density; PC, Phosphorylcholine; PTX
Kaposi's sarcoma-associated herpes virus complement control protein: KCP – complement inhibition and more
Keywords: FH، عامل H; C4BP, C4b-binding protein; CCP, complement control protein (domain); CCPH, complement control protein homologue from herpesvirus saimiri; CR1, complement receptor 1; DAF, decay accelerating factor; FH, factor H; HIV, human immunodeficiency virus; FI, fact
Associative and Structural Properties of the Region of Complement Factor H Encompassing the Tyr402His Disease-related Polymorphism and its Interactions with Heparin
Keywords: FH، عامل H; FH, factor H; SCR, short complement regulator; AMD, age-related macular degeneration; aHUS, atypical haemolytic uraemic syndromefactor H; X-ray scattering; homology modelling; ultracentrifugation
Localization of the third heparin-binding site in the human complement regulator factor H1
Keywords: FH، عامل H; aHUS, atypical haemolytic uremic syndrome; AP, alternative pathway; fH, factor H; GAG, glycosaminoglycan; HUVEC, human umbilical vein endothelial cell; SCR, short consensus repeatComplement; Alternative pathway; Heparin-binding
The 15 SCR Flexible Extracellular Domains of Human Complement Receptor Type 2 can Mediate Multiple Ligand and Antigen Interactions
Keywords: FH، عامل H; BCR, B cell receptor; CR2, complement receptor type 2; PBS, phosphate buffered saline; SCR, short complement regulator; FH, Factor H; NP, 4-hydroxy-3-nitrophenylanalytical ultracentrifugation; constrained modelling; neutron scattering; short complement re