Keywords: سینتیک انعطاف پذیر; Folding kinetics; Folding rate; Folding time; Protein folding; Molecular dynamics; Survival analysis; Ï; folding time; MD; molecular dynamics; CαRMSD; Cα root mean square deviation; 95%CI; 95% confidence interval; CαβRMSD; Cα and Cβ root mean squar
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High-pressure NMR techniques for the study of protein dynamics, folding and aggregation
Keywords: سینتیک انعطاف پذیر; High-pressure; Protein folding; Folding kinetics; Intermediate states; Protein aggregation;
Biomolecular dynamics studied with IR-spectroscopy using quantum cascade lasers combined with nanosecond perturbation techniques
Keywords: سینتیک انعطاف پذیر; T-jump; pH-Jump; Infrared spectroscopy; Quantum cascade laser; Folding kinetics; Poly-l-glutamic acid;
Rapid three-dimensional microfluidic mixer for high viscosity solutions to unravel earlier folding kinetics of G-quadruplex under molecular crowding conditions
Keywords: سینتیک انعطاف پذیر; Microfluidic chip; Micromixer; Folding kinetics; G-quadruplex
The E. coli thioredoxin folding mechanism: The key role of the C-terminal helix
Keywords: سینتیک انعطاف پذیر; CD; circular dichroism; CTH; C-terminal α-helix; DLS; dynamic light scattering; ESI-MS; electrospray ionization mass spectrometry; GdmCl; guanidinium chloride; HB; hydrogen bond; Iâ and Iâ-sim; high energy intermediate state inferred from experiments
A Hooke׳s law-based approach to protein folding rate
Keywords: سینتیک انعطاف پذیر; Folding kinetics; Folding degree; Elastic folding constant; PROTDCAL;
Probing the energetic and kinetic impact of topologically conserved interactions in the SIV gp41 six-helix bundle
Keywords: سینتیک انعطاف پذیر; SIV gp41; Folding kinetics; Protein stability; Transition state;
An expanded view of the protein folding landscape of PDZ domains
Keywords: سینتیک انعطاف پذیر; nNOS, neuronal nitric oxide synthase; PDZ, PSD-95/Discs large/ZO-1; PSD-95, postsynaptic density protein-95PDZ domain; Protein folding; Folding kinetics; Transition state; β-Tanford
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state
Keywords: سینتیک انعطاف پذیر; Membrane protein; Protein folding; Folding kinetics; SDS
Folding kinetic pathway of phosphofructokinase-2 from Escherichia coli: A homodimeric enzyme with a complex domain organization
Keywords: سینتیک انعطاف پذیر; Phosphofructokinase; Folding pathway; Subunit association; Bimolecular domain; Ribokinase-like family; Subunit interface; Folding kinetics; Pfk-2; phosphofructokinase-2; GdnHCl; guanidine hydrochloride; DTT; dithiotreitol; CD; circular dichroism scpectros
Kinetic Folding Mechanism of an Integral Membrane Protein Examined by Pulsed Oxidative Labeling and Mass Spectrometry
Keywords: سینتیک انعطاف پذیر; folding kinetics; folding intermediate; covalent labeling; hydroxyl radical; stopped-flow spectroscopyBR, bacteriorhodopsin; BO, bacterioopsin (BR without retinal chromophore); Chaps, 3-[(3-cholamidopropyl)dimethylammonio]propanesulfonic acid; DMPC, l-α-1
Folding kinetics of two-state proteins based on the model of general random walk in native contact number space
Keywords: سینتیک انعطاف پذیر; 87.15.Cc; 87.15.hmProtein folding; Folding rate; Native contact; Folding kinetics; Random walk model
Measuring “Unmeasurable” Folding Kinetics of Proteins by Single-Molecule Force Spectroscopy
Keywords: سینتیک انعطاف پذیر; AFM, atomic force microscopy; WLC, worm-like chain; PBS, phosphate-buffered salinesingle-molecule force spectroscopy; protein folding; irreversible denaturation; folding kinetics; atomic force microscopy
Dissecting structural transitions in the HIV-1 dimerization initiation site RNA using 2-aminopurine fluorescence
Keywords: سینتیک انعطاف پذیر; HIV-1; Dimerization initiation site (DIS); Viral genome dimerization; RNA-RNA 'kissing' interaction; Folding kinetics; Equilibrium binding; 2-Aminopurine fluorescence;
Simulating RNA Folding Kinetics on Approximated Energy Landscapes
Keywords: سینتیک انعطاف پذیر; MC, Monte Carlo; MME, map-based master equation; MMC, map-based Monte Carlo; PBS, probabilistic Boltzmann-filtered suboptimal sampling; BPE, base-pair enumeration; SPE, stack-pair enumeration; WT, wild typeRNA folding; folding kinetics; motion planning; m
Sequential Barriers and an Obligatory Metastable Intermediate Define the Apparent Two-state Folding Pathway of the Ubiquitin-like PB1 Domain of NBR1
Keywords: سینتیک انعطاف پذیر; PB1, N-terminal Phox and Bem1p; TS, transition stateprotein folding; metastable intermediate; thermodynamics; transition states; folding kinetics
Thermodynamics, Kinetics, and Salt dependence of Folding of YopM, a Large Leucine-rich Repeat Protein
Keywords: سینتیک انعطاف پذیر; ANK, ankyrin; TPR, tetratricopeptide; LRR, leucine-rich repeat; ASA, accessible surface area; SVD, singular value decompositionrepeat-protein; leucine-rich repeat; cooperative folding; electrostatics; folding kinetics
Protein folding: Then and now
Keywords: سینتیک انعطاف پذیر; Protein folding; Misfolding; Aggregation; Folding kinetics; Protein thermodynamics; Discrete molecular dynamics (DMD);
Thermodynamic and Kinetic Characterization of ApoHmpH, a Fast-Folding Bacterial Globin
Keywords: سینتیک انعطاف پذیر; Hmp, flavohemoglobin; HmpH, heme domain of Hmp; apoHmpH, apo form of HmpH; Mb, myoglobin; apoMb, apomyoglobin; CD, circular dichroism; water-sLED, water-suppressed longitudinal encode–decodeapoHmpH; E. coli; globin; folding kinetics; thermodynamic stabili
Plasticity of the protein folding landscape: Switching between on- and off-pathway intermediates
Keywords: سینتیک انعطاف پذیر; Protein folding; Intermediate; Transition state; Chevron plot; Folding kinetics; Cytochromes c; Hydrogenobacter thermophilus;
Identification and characterization of protein folding intermediates
Keywords: سینتیک انعطاف پذیر; Protein folding; Intermediate; Transition state; Folding kinetics; Mutagenesis;
Folding Mechanism of an Ankyrin Repeat Protein: Scaffold and Active Site Formation of Human CDK Inhibitor p19INK4d
Keywords: سینتیک انعطاف پذیر; ANK, ankyrin repeat; CDK, cyclin D-dependent kinase; H/D, hydrogen/deuterium; HSQC, heteronuclear single quantum coherenceankyrin repeat; protein folding; p19INK4d; folding intermediate; folding kinetics
The Folding Pathway of an FF domain: Characterization of an On-pathway Intermediate State Under Folding Conditions by 15N, 13Cα and 13C-methyl Relaxation Dispersion and 1H/2H-exchange NMR Spectroscopy
Keywords: سینتیک انعطاف پذیر; CPMG, Carr-Purcell-Meiboom-Gill; SQ, single-quantum; HSQC, heteronuclear single-quantum coherence; WT, wild-typeNMR; CPMG; chemical exchange; relaxation dispersion; folding kinetics
Correlation of folding kinetics with the number and isomerization states of prolines in three homologous proteins of the RNase family
Keywords: سینتیک انعطاف پذیر; Protein folding; Proline isomerization; Ribonuclease family; Structurally homologous proteins; Folding kinetics; Conformational folding
Observing Folding Pathways and Kinetics of a Single Sodium-proton Antiporter from Escherichia coli
Keywords: سینتیک انعطاف پذیر; atomic force microscopy; single-molecule force spectroscopy; sodium/proton antiporter; folding kinetics; molecular interactionsAFM, atomic force microscopy; F–D, force–distance; kfold, folding rate; NhaA, sodium/proton antiporter; WLC, worm-likechain
Acid-induced unfolding kinetics in simulated gastric digestion of proteins
Keywords: سینتیک انعطاف پذیر; Simulated gastric fluid; Digestion; Folding kinetics
Surprisingly High Correlation between Early and Late Stages in Non-two-state Protein Folding
Keywords: سینتیک انعطاف پذیر; protein folding; folding kinetics; non-two-state protein; folding intermediate; backbone topologykI, the rate constant for the formation of the folding intermediate in non-two-state proteins; kN, the rate constant for the formation of the native state in
Nanopore–Protein Interactions Dramatically Alter Stability and Yield of the Native State in Restricted Spaces
Keywords: سینتیک انعطاف پذیر; macromolecular crowding; chaperonins; folding in confined spaces; folding kinetics; nanopore–protein interactionsSP, substrate protein; NBA, native basin attraction; MG, molten globule; SIS, surface interaction-stabilized; DAC, dynamic Anfinsen cage; DSE,
The Major Outer Membrane Protein of Fusobacterium nucleatum (FomA) Folds and Inserts into Lipid Bilayers via Parallel Folding Pathways
Keywords: سینتیک انعطاف پذیر; folding kinetics; membrane protein folding; insertion; outer membrane protein; β-barrel membrane proteinBR, bacteriorhodopsin; CD, circular dichroism; diC10:0PC, 1,2-dicapryl-sn-glycero-3-phosphocholine; diC18:1PC, 1,2-dioleoyl-sn-glycero-3-phosphocholine
Rapid binding of copper(I) to folded aporusticyanin
Keywords: سینتیک انعطاف پذیر; Blue copper proteins; Copper uptake; Rusticyanin; Protein folding; Folding kinetics
The mechanism of PNIPAAm-assisted refolding of lysozyme denatured by urea
Keywords: سینتیک انعطاف پذیر; Poly(N-isopropyl acylamide); Lysozyme; Refolding in vitro; Folding kinetics; Protein downstream process;
Matrix assisted refolding of proteins by ion exchange chromatography
Keywords: سینتیک انعطاف پذیر; α-Lactalbumin; On column refolding; DEAE Sepharose; Folding kinetics; Matrix assisted refolding;