Keywords: فراکسیون جذب می شود; fraction absorbed; pharmacokinetics; PBPK; absorption; absorption efficiency; %Fa; modeling;
مقالات ISI فراکسیون جذب می شود (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: فراکسیون جذب می شود; ADAM; advanced dissolution, absorption, and metabolism; AED; antiepileptic drug; AUC; area-under-the-curve; B/P; blood to plasma ratio; BID; twice daily; BMI; body mass index; CBZ; carbamazepine; CLint; intrinsic clearance; CLR; renal clearance; CL; clear
Keywords: فراکسیون جذب می شود; Cyclodextrins; Risk analysis; Pharmacokinetics; Modelling; Fraction absorbed; Oral absorption; Rats;
Keywords: فراکسیون جذب می شود; BCS; Fraction absorbed; Oral absorption; Heterogeneous; Variability;
In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey
Keywords: فراکسیون جذب می شود; In vitro-in vivo extrapolation; gut first-pass extraction; fraction absorbed; portal vein-cannulated monkey; intestine S9; carboxylesterase; CAT; compartmental absorption and transit model; CES; carboxylesterase; CLint; intrinsic clearance; Fa; frac
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes
Keywords: فراکسیون جذب می شود; AFE; Average Fold Error; AAFE; Absolute Average Fold Error; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CCC; Concordance Correlation Coeffici
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results
Keywords: فراکسیون جذب می شود; API; Active pharmaceutical ingredient; AUC; Area under the curve; BCS; Biopharmaceutics classification system; BE; Bioequivalence; BP; Blood-to-plasma ratio; CL; Clearance; CL/F; Apparent clearance; Cmax; Maximum concentration; Do; Dose number; fa; Fracti
Determinants of Intestinal Availability for P-glycoprotein Substrate Drugs Estimated by Extensive Simulation With Mathematical Absorption Models
Keywords: فراکسیون جذب می شود; drug-drug interaction; P-glycoprotein; physiologically based pharmacokinetic model; modeling and simulation; intestinal absorption; substrate drug; CLh; hepatic clearance; CLr; renal clearance; CYP3A; cytochrome P450 3A; DDI; drug-drug interaction; EQ
Single-Pass Intestinal Perfusion (SPIP) and prediction of fraction absorbed and permeability in humans: A study with antiretroviral drugs
Keywords: فراکسیون جذب می شود; Intestinal absorption; Permeability; Drug transport; Paracellular transport; Passive diffusion/transport; Fraction absorbed;
In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model
Keywords: فراکسیون جذب می شود; colon absorption; fraction absorbed; permeability; absorption; colonic drug delivery; in vitro models; Caco-2 cells; site-specific absorption
An interesting relationship between drug absorption and melting point
Keywords: فراکسیون جذب می شود; Absorption; Absorption potential; Bioavailability; Dose; Fraction absorbed; Melting point; Partition coefficient; Passive absorption; Solubility; Suspension
P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model
Keywords: فراکسیون جذب می شود; ab; apical to basolateral; AQ; absorptive quotient; AUCT; area under the curve; ba; basolateral to apical; ClR; renal clearance; Cmax; maximum plasma concentration; CYP; cytochrome P450; ER; efflux ratio; F; fraction not metabolised; FA; fraction absorbed
Prediction of Absorbability of Poorly Water-soluble Drugs Based on Permeability Obtained through Modified In Vitro Chamber Method
Keywords: فراکسیون جذب می شود; poorly water-soluble drugs; permeability; dimethyl sulfoxide; intestinal tissue; fraction absorbed;