Keywords: ضخامت کامل; In vitro genotoxicity; Comet assay; Skin; Phenion®FT; DNA damage; Dermal exposure; AK; adenylate kinase; ALI; air-liquid-interface; APC; aphidicolin; BaP; benzo[a]pyrene; EURL-ECVAM; European Union Reference Laboratory for alternatives to animal testing;