A pharmacologic activator of endothelial KCa channels increases systemic conductance and reduces arterial pressure in an anesthetized pig model
Keywords: G, conductance; HR, heart rate; IVC, inferior vena cava; KCa channel, calcium-activated K+ channel; mPAO, mean aortic pressure; mPIVC, mean inferior vena caval pressure; PBS, phosphate-buffered saline; PLVED, left ventricular end-diastolic pressure; SKA-3