Keywords: TCNB, 2,4,6-trinitrochlorobenzene; ARs, adrenergic receptors; APC, antigen presenting cell; BM, bone marrow; BMDC, BM-derived DCs; CNS, central nervous system; CTL, cytotoxic T lymphocytes; DCs, dendritic cells; G-proteins, GTP-binding proteins; GPCRs, G-