Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: A key to oxidative stress induced by non-steroidal anti-inflammatory drugs?
Keywords: G6PD، گلوکز 6-فسفات دهیدروژناز; COX, cyclooxygenase; DHEA, dehydroepiandrosterone; G6PD, glucose-6-phosphate dehydrogenase; KPF, ketoprofen; NAK, non-acylating analogue of KPF–CoA; NSAID, non-steroidal anti-inflammatory drugs; PEP, phospho(enol)pyruvate monopotassium; ROS, reactive oxyg