Keywords: Phytosterol; 4-Nitrophenol; Rat; Liver; Oxidative stressAKP, aryl hydrocarbon receptor; ALT, alkaline transaminase; AST, aspartate transaminase; CAT, catalase; GCLC, glutamate cysteine ligase catalytic subunit; GSH-PX, glutathione peroxidase; HEh, ematoxy
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Rice protein suppresses ROS generation and stimulates antioxidant gene expression via Nrf2 activation in adult rats
Keywords: ALT, alanine transaminase; ARE, antioxidant response element; AST, aspartate transaminase; CAS, casein; CAS-C, cholesterol-supplemented casein; GCL, glutamate cysteine ligase; GCLC, glutamate cysteine ligase catalytic subunit; GCLM, glutamate cysteine lig
Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet
Keywords: CD36, cluster of differentiation 36; Fas, fatty acid synthase; Fgf21, fibroblast growth factor 21; Gclc, glutamate cysteine ligase catalytic subunit; GST, glutathione S-transferase; Keap1, Kelch-like ECH-associated protein 1; K1-kd, Keap1-knockdown; MCD,
CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes
Keywords: ALT, Alanine transaminase; CDDO-Im, 2-cyano-3,12 dioxooleana-1,9 diene-28-imidazolide; Gclc, Glutamate cysteine ligase catalytic subunit; GSH, Glutathione; Ho-1, Heme oxygenase-1; Keap1, Kelch-like ECH associated protein 1; Maf, Musculo-aponeurotic fibros
Oleanolic acid activates Nrf2 and protects from acetaminophen hepatotoxicity via Nrf2-dependent and Nrf2-independent processes
Keywords: ALT, alanine transaminase; ARE, antioxidant response element; ATF-4, activating transcription factor-4; Cul3, Cullin3; Gclc, glutamate cysteine ligase catalytic subunit; Ho-1, heme oxygenase-1; MT, metallothionein; Nrf2, nuclear factor-erythroid 2-related
Renal protection by 3H-1,2-dithiole-3-thione against cisplatin through the Nrf2-antioxidant pathway
Keywords: D3T, 3H-1,2-dithiole-3-thione; Nqo1, NAD(P)H:quinone oxidoreductase 1; GCLC, glutamate cysteine ligase catalytic subunit; GCLM, glutamate cysteine ligase modifier subunit; BSO, L-buthionine-sulfoxamine; DTNB, 5′,5-dithio-bis(2-nitrobenzoic acid); MTT, 3-(
Role of the Nrf2-antioxidant system in cytotoxicity mediated by anticancer cisplatin: Implication to cancer cell resistance
Keywords: Nqo1, NAD(P)H:quinine oxidoreductase 1; GCLC, glutamate cysteine ligase catalytic subunit; GCLM, glutamate cysteine ligase modifier subunit; BSO, l-buthionine-sulfoxamine; NAC, N-acetyl-l-cysteine; DTNB, 5′,5-dithiobis(2-nitrobenzoic acid); MTT, MTT 3-(4,
Effects of 6-hydroxydopamine on mitochondrial function and glutathione status in SH-SY5Y human neuroblastoma cells
Keywords: CCCP, carbonylcyanide-m-chlorophenylhydrazone; DMEM, Dulbecco's minimum essential medium; GCL, glutamate cysteine ligase; GCLC, glutamate cysteine ligase catalytic subunit; GCLM, glutamate cysteine ligase modifier subunit; GPX, glutathione peroxidase; G