
Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphoruscarbon bond cleavage
Keywords: Schiff-base; Phosphoryl transfer; Phosphoenzyme; Phosphoaspartate; Structural enzymology; HAD superfamily; General acid catalysis; General base catalysis; Enamine; Phosphate ester hydrolysis; Phosphonatase; Phosphonate; Cap domain; Core domain; Electrophi