Keywords: GLP-1، پپتید مشابه گلوکاگون 1; Resistant starch; VAS; Ghrelin; Peptide YY; Energy consumption; Insulin sensitivityAS, available starch; AUC, area under the curve; BMI, body mass index; DF, dietary fibre; FFA, free fatty acid; GLP-1, glucagon-like peptide 1; GTT, glucose tolerance test;
مقالات ISI GLP-1، پپتید مشابه گلوکاگون 1 (ترجمه نشده)
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Keywords: GLP-1، پپتید مشابه گلوکاگون 1; Neonatal weight gain; Maternal high-fat diet; Insulin; Incretin; GhrelinPND, postnatal day; GLP-1, glucagon-like peptide 1; GIP, glucose-dependent insulinotropic polypeptide; GOAT, ghrelin-O-acyltransferase; Pdx-1, pancreas duodenum homeobox-1; Ghrl, ghre
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GWAS, genome-wide association study; GLP-1, glucagon-like peptide 1; GIP, glucose-dependent insulinotropic peptide; GIPR, GIP receptor; GLP1R, GLP-1 receptor; DPP4, dipeptidyl peptidase 4; GCG, proglucagon gene; PCSK1, prohormone convertase (PC) enzymes.
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, Glucagon-like peptide 1; GLP-1R, GLP-1 receptor; CT, Calcitonin; bCT, basal Calcitonin; sCT, stimulated Calcitonin; T2DM, Type 2 diabetes mellitus; CCH, C-cells hyperplasia; MTC, Medullary thyroid cancer; OAD, Oral antidiabetics; FAT, Fat mass; FFM
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; Lactococcus lactis; Glucose tolerance; Recombinant bacteria; GLP-1cfu, Colony forming unit; DPP4, Dipeptidyl peptidase 4; G-KRB, glucose-Krebs ringer buffer; GLP-1, Glucagon-like peptide 1; GLP1R-KO, GLP-1 receptor knock out; G6pc, glucose 6 phosphatase,
Berberine induces GLP-1 secretion through activation of bitter taste receptor pathways
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; BBR, berberine; PTC, phenylthiocarbamide; PLC, Phospholipase C; TRPM5, transient receptor potential cation channel subfamily M member 5; KRB, Krebs-Ringer bicarbonate buffer; FBS, fetal bovine serum; BSA, bovine serum album
Reprint of “Preclinical and clinical effects of Coleus forskohlii, Salacia reticulata and Sesamum indicum modifying pancreatic lipase inhibition in vitro and reducing total body fat”
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; Coleus forskohlii; Salacia reticulate; Sesamum indicum; Pancreatic lipase; Body fatPLT, pancreatic triacylglycerol lipase; CCK, cholecystokinin; PYY, Peptide YY or Peptide tyrosine tyrosine; GLP-1, glucagon-like peptide 1
Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; APAAP, alkaline phosphatase-anti-alkaline phosphatase; DPP-4, dipeptidyl peptidase IV; FCS, fetal calf serum; GAD Ab, glutamic acid decarboxylase 65 antibody; GIP, gastric inhibitory peptide; GLP-1, glucagon-like peptide 1; SSC, side scatterDipeptidyl pep
Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; GLP-2, glucagon-like peptide 2; HD, high dose; iAUC, incremented area under the curve; L. casei W8, Lactobacillus paracasei subsp paracasei L. casei W8 DSM 23686; LD, low dose; PYY, peptide YY; VAS, visual analog scale.Prob
Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a Mouse model of Western diet induced obesity
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; WD, Western Diet; CVD, cardiovascular disease; IR, insulin resistance; MetS, metabolic syndrome; HF, heart failure; LV, left ventricle; ROS, reactive oxygen species; RAAS, renin–angiotensin–aldosterone system; GLP-1, glucagon-like peptide 1; GIP, glucose-
Pancreatic polypeptide and peptide YY3–36 induce Ca2+ signaling in nodose ganglion neurons
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; CAP, capsaicin; CCK, cholecystokinin; [Ca2+]i, cytosolic Ca2+ concentration; GLP-1, glucagon-like peptide 1; HKRB, HEPES-buffered Krebs–Ringer bicarbonate buffer; MEM, hypothalamic minimal essential medium; NPY, neuropeptide Y; PYY, peptide YY; PP, pancre
Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; BMI, Body mass index; Cas-meal, Casein meal; CVD, Cardiovascular disease; iAUC, Incremental area under the curve; GIP, Glucose-dependent insulinotropic peptide; GLP-1, Glucagon-like peptide 1; Glu-meal, Gluten meal; HDL, High density lipoproteins; I-tg, I
Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; DM, diabetes mellitus; GFLX, gatifloxacin; STZ, streptozotocin; KATP channel, ATP-sensitive K+ channel; SUR, sulfonylurea receptor; KRB, Krebs-Ringer bicarbonate buffer; FBS, fetal bovine serum; BSA, bovine serum albumin; D
Epigenomic regulation of bile acid metabolism: Emerging role of transcriptional cofactors
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; FXR, farnesoid X Receptor; PTM, post-translational modification; NR, nuclear receptor; DBD, DNA binding domain; LBD, ligand binding domain; GPCR, G-protein coupled receptor; GLP-1, glucagon-like peptide 1; ChIP, chromatin immunoprecipitation; Cyp7a1, chol
Regulation of chylomicron production in humans
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; apo, apolipoprotein; CM, chylomicron; CVD, cardiovascular disease; FFA, free fatty acids; GIP, gastric inhibitory polypeptide; GLP-1, glucagon-like peptide 1; HL, hepatic lipase; LPL, lipoprotein lipase; MTP, microsomal triglyceride transfer protein; T1D,
Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AUC, area under the curve; ANOVA, analysis of variance; β-cell, beta cell; C, control; CVD, cardiovascular disease; DIO, diet-induced obesity; FFA, free fatty acid; GLP-1, glucagon-like peptide 1; GTT, glucose tolerance test; HFD, high-fat diet; HDL, high
Two incretin hormones GLP-1 and GIP: Comparison of their actions in insulin secretion and β cell preservation
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; Incretin; GIP; GLP-1; diabetes; beta cellDPP-4, dipeptidyl peptidase-4; GIP, glucose-dependent insulinotropic polypepide; GIPR, GIP receptor; GLP-1, glucagon-like peptide 1; GLP-1R, GLP-1 receptor; T2DM, type 2 diabetes; TORC2, transducer of regulated CRE
Soy protein– and casein-based weaning diets differ in effects on food intake and blood glucose regulation in male Wistar rats
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; BW, body weight; C, casein; CC, casein diet throughout; CS, casein followed by soy protein diet; CCK, cholecystokinin; FI, food intake; GLP-1, glucagon-like peptide 1; HOMA-IR, homeostatic model assessment of insulin resistance; I/G, insulin-to-glucose ra
The Effects of an Amino Acid Supplement on Glucose Homeostasis, Inflammatory Markers, and Incretins after Laparoscopic Gastric Bypass
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; CRP, C-reactive protein; GIP, gastric inhibitory polypeptide; GLP-1, glucagon-like peptide 1; HOMA, homeostasis model assessment; IGF-1, insulin-like growth factor 1; LGB, laparoscopic gastric bypass; LBM, lean body mass; QUICKI, quantitative insulin sens
Preproglucagon neurons project widely to autonomic control areas in the mouse brain
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; glucagon-like peptide 1; area postrema; dorsal vagal complex; hypothalamus; green fluorescent protein; immunohistochemistryAP, area postrema; GLP-1, glucagon-like peptide 1; IRT, intermediate reticular nucleus; NHS, normal horse serum; NTS, nucleus tractu
Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; DPP-4, dipeptidyl peptidase IV; T2DM, type 2 diabetes mellitus; GLP-1, glucagon-like peptide 1; SAR, structure–activity relationship; SBDD, structure-based drug design; Boc, tert-butoxy carbonyl; TBS, tert-butyldimethylsilyl; Cbz, benzyloxycarbonyl; ADME,
Biological activity of EXf, a peptide analogue of exendin-4
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; CRE, cAMP response element; RIP1, rat insulin I gene promoter; GLP-1, glucagon-like peptide 1; MSG, monosodium l-glutamate; GFP, green fluorescent protein; MSG-IR mice, monosodium l-glutamate induced insulin resistance mice; AUC0–135, area under curve (0–
Modulation of glucagon-like peptide-1 release by berberine: In vivo and in vitro studies
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; PKC, protein kinase C; PKA, protein kinase A; AMPK, AMP-activated protein kinase; KRB, Krebs–Ringer bicarbonate buffer; FBG, fasted blood glucose; DPP-IV, dipeptidyl peptidase-IV; Compound C, 6-[4-(2-piperidin-1-ylethoxy)ph
A high-fat diet inhibits the progression of diabetes mellitus in type 2 diabetic rats
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AUC, area under the curve; BUN, blood urea nitrogen; CCr, creatinine clearance; CT, computed tomography; SD, Sprague-Dawley; GLP-1, Glucagon-like peptide 1; HF-SDT, SDT rats on high-fat diet; SD-SDT, SDT rats on standard diet; SDT, Spontaneously Diabetic
Novel, non-peptidic somatostatin receptor subtype 5 antagonists improve glucose tolerance in rodents
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; ANOVA, analysis of variance; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUC, area under the curve; BSA, bovine serum albumin; CHO, Chinese hamster ovary; DIO, diet-induced obesity; GLP-1, glucagon-like peptide 1; HOMA, homeostasis mod
Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AngII, angiotensin II; DPP-IV, dipeptidyl peptidase IV; GLP-1, Glucagon-like peptide 1; GLP-1R, Glucagon-like peptide 1 receptor; MAPKinase, mitogen-activated protein kinase; PKCβ, protein kinase Cβ; RAS, renin-angiotensin systemAngiotensin II; db/db mice
Subject Standardization, Acclimatization, and Sample Processing Affect Gut Hormone Levels and Appetite in Humans
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AUC, area under curve; DP-IV, dipeptidyl-peptidase IV; GLP-1, glucagon-like peptide 1; PYY, peptide YY; VAS, visual analogue score
Novel therapeutics for type 2 diabetes: Incretin hormone mimetics (glucagon-like peptide-1 receptor agonists) and dipeptidyl peptidase-4 inhibitors
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; GIP, glucose-dependent insulinotropic peptide (formerly gastrin inhibiting peptide); DPP-4, (dipeptidyl petidase 4); WNT, cell-secreted glycoprotein ligand); PYY, peptide YY; s.c., subcutaneous; min, minute; TNF-α, tumor ne
Novel stable PACAP analogs with potent activity towards the PAC1 receptor
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; PACAP, pituitary adenylate cyclase-activating polypeptide; CNS, central nervous system; VIP, vasoactive intestinal polypeptide; DPP IV, dipeptidyl peptidase IV; GLP-1, glucagon-like peptide 1; RP-HPLC, reverse-phase high-performance liquid chromatography;
Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; βGal, beta-galactosidase; ERK1/2, extracellular signal-regulated kinases 1 and 2; GLP-1, glucagon-like peptide 1; GSK3, glycogen synthase kinase 3; PI3K, phosphatidylinositol 3-kinase; PKB (Akt), protein kinase B; PtdIns(3,4,5)P3, phosphatidylinositol 3,4
Gut Hormones and Appetite Control
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AgRP, agouti-related peptide; CCK, cholecystokinin; CNS, central nervous system; GH, growth hormone; GLP-1, glucagon-like peptide 1; NPY, neuropeptide Y; NTS, nucleus of the solitary tract; POMC, pro-opiomelanocortin; PP, pancreatic polypeptide; PWS, Prad
Using Evolutionary Information and Ancestral Sequences to Understand the Sequence–Function Relationship in GLP-1 Agonists
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; GLP-1, glucagon-like peptide 1; hGLP-1, human GLP-1(7–37); GLP-1A, Xenopus laevis GLP-1A; DPP-IV, dipeptidyl peptidase IV; ARP, ancestral reconstructed peptide; EMP, evolutionary mapped peptidediabetes; protein family; sequence–function mapping; molecular
In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion
Keywords: GLP-1، پپتید مشابه گلوکاگون 1; AGC, aspartate/glutamate carrier; BCH, beta-2-aminobicyclo[2.2.1]heptane-2-carboxylic acid; GAD, glutamate decarboxylase; GDH, glutamate dehydrogenase; GLP-1, glucagon-like peptide 1; KATP-channel, ATP-sensitive K+ channel; LCPT1, liver carnitine palmitoy