Persistence of cirrhosis is maintained by intrahepatic regulatory T cells that inhibit fibrosis resolution by regulating the balance of tissue inhibitors of metalloproteinases and matrix metalloproteinases
Keywords: α-SMA; α-smooth muscle actin; CCl4; carbon tetrachloride; CTL; cytotoxic lymphocyte; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; DMEM; Dulbecco modified Eagle medium; ECM; extracellular matrix; FACS; fluorescence activated cell sorting; GITR;