دانلود مقالات ISI درباره Gof, Gain-Of-Function + ترجمه فارسی

توسعه و تایید یک سیستم توالی نسل بعدی مقیاس پذیر برای ارزیابی گزینه های اجتماعی مرتبط در تومورهای جامد 12

Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors 12

Keywords: AOHC, AcroMetrix Oncology Hotspot Control; CNAs, copy number alterations; FFPE, formalin-fixed paraffin-embedded; GoF, gain-of-function; indels, insertions/deletions; LoF, loss-of-function; LU, lung cohort; MCR, minimal common region; MO, molecular cohort

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

A novel gain-of-function STAT1 mutation resulting in basal phosphorylation of STAT1 and increased distal IFN-γ-mediated responses in chronic mucocutaneous candidiasis

Keywords: CMC, chronic mucocutaneous candidiasis; STAT1, signal transducer and activator of transcription 1; P-STAT1, phosphorylated STAT1; GOF, gain-of-function; CCD, coiled-coil domain; DBD, DNA binding domain; IL, interleukin; IFN, interferon; IP-10, IFN-gamma-i

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival 1

Keywords: CASP3, caspase 3; CDKN1A, cyclin dependent protein kinase 1, P21; CNV, copy number variation; DNAJC3, DnaJ homolog subfamily C; GFP, green fluorescent protein; GOF, gain-of-function; HGSC, high-grade serous ovarian cancer; HOX, homeobox genes; LOH, loss o

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Evidence that the C-terminal region is involved in the stability and functionality of OprM in E. coli

Keywords: Multidrug-resistant efflux pumps; Gain-of-function mutations; OprM; C-terminal domainMDR, multidrug-resistant; gof, gain-of-function; OEP, outer efflux protein; CMT, cytoplasmic membrane translocase; MFP, membrane fusion proteins; RND, Resistance-Nodulati

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Progress and challenges in the study of α6-containing nicotinic acetylcholine receptors

Keywords: α-Ctx, alpha-conotoxin; CNS, central nervous system; GoF, gain-of-function; KO, knock-out; LC, locus coeruleus; MPTP, 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine; nAChRs, nicotinic acetylcholine receptors; PD, Parkinson's disease; PET, positron emission

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Properties of the intracellular transient receptor potential (TRP) channel in yeast, Yvc1

Keywords: DIDS, 4,4-diisothiocyanato-stilbene-2,2-disulfonic acid; DTT, dithiothreitol; GFP, green fluorescent protein; GOF, gain-of-function; InsP3, inositol 1,4,5-triphosphate; Pmc1, vacuolar Ca2+-ATPase; TM, transmembrane domain; TRP, transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Pore Mutations of the Escherichia coli MscS Channel Affect Desensitization but Not Ionic Preference

Keywords: MS, mechanosensitive; GOF, gain-of-function; TM, transmembrane

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Disulfide Trapping the Mechanosensitive Channel MscL into a Gating-Transition State

Keywords: MS, mechanosensitive; TM, transmembrane domain; GOF, gain-of-function; LOF, loss-of-function; E. coli, Escherichia coli; DTT, dithiothreitol; OD, optical density; Po, open probability

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Conditional and inducible gene recombineering in the mouse inner ear

Keywords: GOF, gain-of-function; GOI, gene-of-interest; LOF, loss-of-function; FLPe, efficient Flp recombinase; β gal, β galactosidase; PCR, polymerase chain reaction; IRES, internal ribosome entry site; BAC, Bacterial Artificial Chromosome; ER, estrogen receptorRe

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه