Keywords: Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
مقالات ISI (ترجمه نشده)
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Keywords: Atherosclerosis; Rabbit model; Ascending aorta; Proteomics; iTRAQ; Histology; Gpnmb;
DLG2, but not TMEM229B, GPNMB, and ITGA8 polymorphism, is associated with Parkinson's disease in a Taiwanese population
Keywords: Transmembrane protein; TMEM229B; GPNMB; ITGA8; DLG2; Parkinson's disease; Polymorphism; Disease association;
Validating glycoprotein non-metastatic melanoma B (gpNMB, osteoactivin), a new biomarker of Gaucher disease
Keywords: gpNMB; Osteoactivin; Biomarker; Gaucher disease;
Glycoprotein Non-Metastatic Melanoma Protein B (GPNMB) and Cancer: A Novel Potential Therapeutic Target
Keywords: GPNMB; Melanoma; Breast cancer; Invasion; Matrix metalloproteinase; Antibody-drug conjugate;
Increased GPNMB, phospho-ERK1/2, and MMP-9 in cystic fibrosis in association with reduced arylsulfatase B
Keywords: N-acetylgalactosamine-4-sulfatase; Glycosaminoglycans; Sulfatase; β-1 integrin; ARSB; arylsulfatase B N-acetylgalactosamine-4-sulfatase; BEC; bronchial epithelial cells; C4S; chondroitin 4-sulfate; CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress
Keywords: Parkinson's disease; Lysosome; GPNMB; Glucocerebrosidase; Lipidopathy; Post-mortem;
Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview
Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C
The laminin-derived peptide C16 regulates GPNMB expression and function in breast cancer
Keywords: Breast cancer; Extracellular matrix; Basement membrane; Laminin, C16; GPNMB;
Targeting GPNMB with glembatumumab vedotin: Current developments and future opportunities for the treatment of cancer
Keywords: AE; Adverse Event; α-MSH; alpha-Melanocyte Stimulating Hormone; ADC; Antibody-Drug Conjugate; ASPS; Alveolar Soft Part Sarcoma; ASPSCR1; Alveolar Soft Part Sarcoma Chromosome Region Candidate 1; BMP-2; Bone Morphogenetic Protein-2; BRK; Breast Tumor Kina
No association of GPNMB rs156429 polymorphism with Parkinson's disease, amyotrophic lateral sclerosis and multiple system atrophy in Chinese population
Keywords: Parkinson's disease; Amyotrophic lateral sclerosis; Multiple system atrophy; GPNMB; rs156429 polymorphism;
Glycoprotein nonmetastatic melanoma protein B (GPNMB) as a novel neuroprotective factor in cerebral ischemia-reperfusion injury
Keywords: ALS; amyotrophic lateral sclerosis; EDTA; ethylenediaminetetraacetic acid; ERK1/2; extracellular signal-regulated kinase 1 and 2; GFAP; Glial fibrillary acidic protein; GPNMB; glycoprotein nonmetastatic melanoma protein B; IHC; immunohistochemistry; IRI;
GPNMB/OA protein increases the invasiveness of human metastatic prostate cancer cell lines DU145 and PC3 through MMP-2 and MMP-9 activity
Keywords: PCa; prostate cancer; GPNMB; non-metastatic glycoprotein melanoma protein B; OA; osteoactivin; MMPs; metalloproteinases; TIMPs; tissue inhibitors of matrix metalloproteinases; NGF; Nerve Growth Factor; Q-RT-PCR; quantitative real time-PCR; siRNA; small in
Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate
Keywords: Melanoma; CR011-vcMMAE; Antibody-drug conjugate; GPNMB