دانلود مقالات ISI درباره GSK، glycogen synthase kinase + ترجمه فارسی

بازسازی سیستم عصبی مرکزی آسیب دیده از طریق تکنولوژی مجدد برنامه ریزی: مفاهیم پایه و کاربرد بالقوه برای درمان جایگزینی سلول

Regeneration of the damaged central nervous system through reprogramming technology: Basic concepts and potential application for cell replacement therapy

Keywords: GSK، glycogen synthase kinase; cAMP, cyclic AMP; C/EBP, CCAAT-enhancer-binding protein; CNS, central nervous system; EB, embryoid body; EGF, epidermal growth factor; ES cell, embryonic stem cell; FGF-2, fibroblast growth factor-2; GSK, glycogen synthase kinase; iNSC, induced neural ste

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

مهار پروتئازوما باعث کمبود حمل و نقل وابسته به کیناز است؟ پیامدهای بیماری آلزایمر

Proteasome inhibition induces stress kinase dependent transport deficits — Implications for Alzheimer's disease

Keywords: GSK، glycogen synthase kinase; Aβ, β-amyloid; AD, Alzheimer's disease; APP, amyloid precursor protein; CDK, cyclin dependent kinase; ECM, extracellular matrix; ERK, extracellular signal-regulated protein kinase; GSK, glycogen synthase kinase; MSD, Meso Scale DiscoveryAlzheimer's diseas

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Double stranded viral RNA induces inflammation and insulin resistance in skeletal muscle from pregnant women in vitro

Keywords: GSK، glycogen synthase kinase; TLR, Toll-like receptor; poly(I:C), polyinosinic polycytidilic acid; GDM, gestational diabetes mellitus; NF-κB, nuclear factor-κB; AMPK, adenosine monophosphate activated protein kinase; GSK, glycogen synthase kinase; LDH, lactate dehydrogenase; 2DG, 2-De

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells

Keywords: GSK، glycogen synthase kinase; Bcl, B-cell lymphoma; Bax, Bcl-2-associated X protein; GKA, glucokinase activator; GSK, glycogen synthase kinase; IRS-2, insulin receptor substrate-2; PARP, poly (ADP-ribose) polymerase; VDAC, voltage-dependent anion-selective channel protein; TFAM, mitoc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

6-Gingerol prevents adipogenesis and the accumulation of cytoplasmic lipid droplets in 3T3-L1 cells

Keywords: GSK، glycogen synthase kinase; aP2, fatty acid binding proteins; C/EBP, CCAAT/enhancer-binding protein; DMII, differentiation/induction medium; DMEM, Dulbecco's modified Eagle's medium; FASf, atty acid synthase; FBS, fetal bovine serum; GSK, glycogen synthase kinase; O.D., optical dens

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Ketamine regulates the presynaptic release machinery in the hippocampus

Keywords: GSK، glycogen synthase kinase; Ketamine; SNARE; Synapsin; Synaptotagmin; CaMKII; AntidepressantANOVA, analysis of variance; CaMKII, calcium/calmodulin-dependent protein kinase II; FST, forced swim test; GSK, glycogen synthase kinase; NMDA, N-methyl-d-aspartate; RRP, readily releasable

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo

Keywords: GSK، glycogen synthase kinase; CI, combination index; EC50, half maximal concentration; FBS, fetal bovine serum; FITC, fluoresceinisothiocyanate; GSK, glycogen synthase kinase; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenytetrazolium bromide; NF-κB, nuclear factor-kappa B; PARP, poly (

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Discovering small molecules that inhibit adipogenesis and promote osteoblastogenesis: Unique screening and Oncostatin M-like activity

Keywords: GSK، glycogen synthase kinase; MSC, mesenchymal stem cell; OSM, Oncostatin M; IL-6, Interleukin-6; IL-11, Interleukin-11; LIF, leukemia inhibitory factor; GSK, glycogen synthase kinase; ALP, alkaline phosphatase; PPAR, peroxisome proliferator-activated receptor; Runx, runt-related tran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

β-Amyloid-induced cognitive dysfunction impairs glucose homeostasis by increasing insulin resistance and decreasing β-cell mass in non-diabetic and diabetic rats

Keywords: GSK، glycogen synthase kinase; β-amyloid (25–35), AMY; β-amyloid (35–25), RAMY; partial pancreatectomy, Px; sham-operation, Sham; PKB or Akt, protein kinase B; CREB, cAMP responding element binding protein; GSK, glycogen synthase kinase; BrdU, 5-bromo-2-deoxyuridine; HOMA-IR, Homeostat

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Enhanced apoptotic effects by downregulating Mcl-1: Evidence for the improvement of photodynamic therapy with Celecoxib

Keywords: GSK، glycogen synthase kinase; Mcl-1, myeloid cell leukemia 1; PDT, photodynamic therapy; MEK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; PI3K, phosphatidylinositol 3-kinase; VEGF, vascular epidermal growth factor; GSK, glycogen synthase kinase; COX-2

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes – A role for the transcription factor NFAT and phosphodiesterase 3B

Keywords: GSK، glycogen synthase kinase; CL, CL316,243; GIP, glucose-dependent insulinotropic polypeptide; GSK, glycogen synthase kinase; NFAT, nuclear factor of activated T-cells; PDE, phosphodiesterase; PKB, protein kinase B; T2D, type 2 diabetesOsteopontin; GIP; Adipocytes; NFAT; Phosphodiest

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration

Keywords: GSK، glycogen synthase kinase; Cdk, cyclin-dependent kinase; JNK, c-Jun N-terminal kinase; ERK, extracellular response kinase; GSK, glycogen synthase kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PARP, poly(ADP-ribose) polymerase; CHAPS, 3-[(3-cholamidopropyl)dimethylammonio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of β-catenin

Keywords: GSK، glycogen synthase kinase; APC, adenomatous polyposis coli; LEF/Tcf, leukemia enhancement factor/T cell factor; CK, casein kinase; GSK, glycogen synthase kinase; L, conditioned media from parental L cells; W, conditioned media from L cells stably transfected with Wnt3a; mAb, monocl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Prophylactic lithium alleviates postoperative cognition impairment by phosphorylating hippocampal glycogen synthase kinase-3β (Ser9) in aged rats

Keywords: GSK، glycogen synthase kinase; ANOVA, analysis of variance; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSK, glycogen synthase kinase; IL-1β, interleukin-1β; LTP, long-term potentiation; mTOR, mammalian target of rapamycin; mTORC2, mammalian target of rapamycin complex 2; MWM, Mor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Characterization of the effect of TIMAP phosphorylation on its interaction with protein phosphatase 1

Keywords: GSK، glycogen synthase kinase; TIMAP; Protein phosphatase 1; Moesin; Surface plasmon resonanceBPAEC, Bovine pulmonary artery endothelial cell; GSK, Glycogen synthase kinase; EC, Endothelial cell; ERM, Ezrin–radixin–moesin proteins; HPAEC, Human pulmonary artery endothelial cell; IP, Im

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The mitochondrial permeability transition pore and cyclophilin D in cardioprotection

Keywords: GSK، glycogen synthase kinase; ANT, adenine nucleotide translocase; CsA, cyclosporine A; CyP, cyclophilin; Drp1, dynamin-related protein 1; Δψm, mitochondrial membrane potential; ERK, extracellular signal regulated kinase; GSK, glycogen synthase kinase; IMM, inner mitochondrial membran

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Role of Wnt/β-catenin signaling in liver metabolism and cancer

Keywords: GSK، glycogen synthase kinase; LRP, low density lipoprotein (LDL) related protein; GSK, glycogen synthase kinase; APC, adenomatous polyposis coli; CK, casein kinase; TCF, T-cell factor; LEF, Lymphoid enhancing factor; βTrCP, β-transducin repeat-containing protein; DKK, dickkopf; FRP, f

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Proliferative and androgenic effects of indirubin derivatives in LNCaP human prostate cancer cells at sub-apoptotic concentrations

Keywords: GSK، glycogen synthase kinase; LNCaP cells; MDA-kb2 cells; GSK-3β; Androgenic; β-Catenin; IndirubinsCDK, cyclin-dependent kinase; DEX, dexamethasone; DHT, dihydrotestosterone; FLUT, flutamide; GSK, glycogen synthase kinase; MIF, mifepristone; MTT, (3-(4,5-dimethylthiazol-2-yl))-2,5-dip

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

β-Catenin and p120 Mediate PPARδ-Dependent Proliferation Induced by Helicobacter pylori in Human and Rodent Epithelia

Keywords: GSK، glycogen synthase kinase; Stomach Cancer; Mongolian Gerbils; Signaling; BacteriaAPC, adenomatous polyposis coli; GSK, glycogen synthase kinase; mmp, matrix metalloproteinase; p120, p120-catenin; PI3K, phosphatidylinositol 3-phosphate kinase; PPAR, peroxisome proliferator-activated

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

β-Catenin independent cross-control between the estradiol and Wnt pathways in osteoblasts

Keywords: GSK، glycogen synthase kinase; DBD, DNA binding domain; GSK, glycogen synthase kinase; RE, response element; RT-PCR, real time polymerase chain reaction; Runx, runt homology domain transcription factor; TCF, T cell factor; WAg, Wnt pathway agonist17βE; Estrogen receptor; TCF-4; Runx2;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه

Association between glycogen synthase kinase-3β gene polymorphisms and major depression and suicidal behavior in a Korean population

Keywords: GSK، glycogen synthase kinase; GSK, Glycogen synthase kinase; HDRS, Hamilton's Depression Rating Scale; LD, Linkage disequilibrium; MDD, Major depressive disorder; SNP, Single nucleotide polymorphismDepression; GSK-3β; Polymorphism; Suicide

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Snail transcription factors in keratinocytes: Enough to make your skin crawl

Keywords: GSK، glycogen synthase kinase; CK, calmodulin kinase; COX2, cyclooxygenase-2; ECM, extracellular matrix; EGFR, epidermal growth factor receptor; EMT, epithelial–mesenchymal transition; ERK, extracellular regulated kinase; GSK, glycogen synthase kinase; HNSCC, head and neck squamous cel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

In utero exposure to di-(2-ethylhexyl) phthalate affects liver morphology and metabolism in post-natal CD-1 mice

Keywords: GSK، glycogen synthase kinase; Ab, antibody; AFP, α-fetoprotein; BF, benzofuran; β-cat, β-catenin; bp, base pairs; Ct, threeshold cycles; CTRL, control; cyt, cytoplasmic; DEHP, di-(2-ethylhexyl) phthalate; GD, gestational day; GSK, glycogen synthase kinase; HB, hepatoblastoma; LOAEL, l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Human DEAD-box protein 3 has multiple functions in gene regulation and cell cycle control and is a prime target for viral manipulation

Keywords: GSK، glycogen synthase kinase; 4eBP, eIF4e-binding protein; aa, amino acid; Cdc, cell division cycle; CRM-1, chromosome maintenance region-1; DDX3, DEAD-box protein 3; eIF, eukaryotic initiation factor; EJC, Exon junction complex; GSK, glycogen synthase kinase; HBV, Hepatitis B virus;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Proviral integration site for Moloney murine leukemia virus 1, but not phosphatidylinositol-3 kinase, is essential in the antiapoptotic signaling cascade initiated by IL-5 in eosinophils

Keywords: GSK، glycogen synthase kinase; Apoptosis; eosinophils; inflammation; IL-5; phosphatidylinositol-3 kinase; proviral integration site for Moloney murine leukemia virusDN, Dominant-negative; ECP, Eosinophil cationic protein; GSK, Glycogen synthase kinase; HA, Hemagglutinin; Jak, Janus kin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Activation of peroxisome proliferator-activated receptor-α prevents glycogen synthase 3β phosphorylation and inhibits cardiac hypertrophy

Keywords: GSK، glycogen synthase kinase; PPAR-α, peroxisome proliferator-activated receptor-α; PI3K, phosphoinositide 3-kinase; GSK, glycogen synthase kinase; Akt, protein kinase B; NFAT, nuclear factor of activated T cells; Ser, serine; FGF, fibroblast growth factor; VEGF, vascular endothelial

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

GSK-3β mediates in the progesterone inhibition of estrogen induced cyclin D2 nuclear localization and cell proliferation in cyclin D1−/− mouse uterine epithelium

Keywords: GSK، glycogen synthase kinase; GSK, glycogen synthase kinase; E2, estradiol-17β; P4, progesterone; CDK, cyclin dependent kinaseCyclin D2; GSK-3β; Estrogen; Progesterone

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

MUC1 inhibits cell proliferation by a β-catenin-dependent mechanism

Keywords: GSK، glycogen synthase kinase; ALI, air–liquid interface; CT, cytoplasmic tail; GSK, glycogen synthase kinase; LEF, lymphoid enhancer factor; TCF, T cell factor; TCL, total cell lysate; TER, transepithelial electrical resistance; TSE, tracheal surface epithelialCyclin D1; c-Myc; E-cadh

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells

Keywords: GSK، glycogen synthase kinase; CK18, cytokeratin 18; DR, death receptor; ERK, extracellular signal-regulated kinase; FLIP, FLICE inhibitory protein; GSK, glycogen synthase kinase; MMP, mitochondrial membrane potential; PI3K, phosphatidylinositol 3-kinase; PKC, protein kinase C; PARP, p

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Glycogen synthase kinase 3β together with 14-3-3 protein regulates diabetic cardiomyopathy: Effect of losartan and tempol

Keywords: GSK، glycogen synthase kinase; ANP, natriuretic peptide; AT1, angiotensin II type 1; BW, body weight; DN, dominant negative; GSK, glycogen synthase kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HW, heart weight; HW/BW, the ratio of HW to BW; JNK, c-Jun NH2 terminal kinase; M

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Upregulation of TNF-alpha production signaling pathways in monocytes from patients with advanced cirrhosis: Possible role of Akt and IRAK-M

Keywords: GSK، glycogen synthase kinase; ELISA, enzyme-linked immunosorbent assay; GSK, glycogen synthase kinase; IRAK, interleukin-1 receptor-associated kinase; MAP kinase, mitogen-activated protein kinase; NF-kappaB, nuclear factor-kappaB; TLR, Toll-like receptorLPS; TNF-alpha; TLR4; MAP kinas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular Mechanisms in Heart Failure : Focus on Cardiac Hypertrophy, Inflammation, Angiogenesis, and Apoptosis

Keywords: GSK، glycogen synthase kinase; Akt, protein kinase B; ERK, extracellular signal-regulated kinases; gp130, glycoprotein 130; GSK, glycogen synthase kinase; IL-6, interleukin-6; JAK, Janus kinase; LIF, leukemia inhibitory factor; LV, left ventricle/ventricular; MHC, myosin heavy chain; M

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Lipid phosphatases as a possible therapeutic target in cases of type 2 diabetes and obesity

Keywords: GSK، glycogen synthase kinase; GSK, glycogen synthase kinase; IRS, insulin receptor substrate; PI3-kinase, phosphatidyl inositol 3-kinase; PKC, protein kinase C; PTEN, phosphatase and tensin homolog deleted on chromosome ten; SHIP2, src homology 2 domain containing inositol 5′-phosphat

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه