Keywords: GSK3، glycogen synthase kinase 3; hAFS, cellshuman amniotic fluid-derived cells; hESCs, human embryonic stem cells; SVZ, subventrical zone; EBs, embryoid bodies; CNS, central nervous system; iPSCs, induced pluripotent stem cells; GSK3, Glycogen synthase kinase 3; NPCs, neural precursor/pr
مقالات ISI GSK3، glycogen synthase kinase 3 (ترجمه نشده)
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Tau pathology-mediated presynaptic dysfunction
Keywords: GSK3، glycogen synthase kinase 3; Cdk5, cyclin-dependent protein kinase 5; ER, endoplasmic reticulum; FAT, fast axonal transport; FTD, frontotemporal dementia; GSK3, glycogen synthase kinase 3; PAD, phosphatase-activating domaintauopathy; IP3 receptor; ryanodine receptor; phosphatase-acti
Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma
Keywords: GSK3، glycogen synthase kinase 3; Apoptosis; NVP-BEZ235; Chloroquine; RhabdomyosarcomaARMS, alveolar RMS; ATTC, American Type Culture Collection; CI, combination index; CQ, chloroquine; ERMS, embryonal rhabdomyosarcoma; FCS, fetal calf serum; GSK3, glycogen synthase kinase 3; mTOR, mammal
Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model
Keywords: GSK3، glycogen synthase kinase 3; Trophoblast; Decidua; Wnt; Paracrine; Dikkopf; Frizzled-related proteinCK, casein kinase; COX, cyclooxygenase; Dkk, dickkopf; DVL, dishevelled; FZD, frizzled; GSK3, glycogen synthase kinase 3; HOXA10, Homeobox A10; LRP, low density lipoprotein receptor-re
PDK1: A signaling hub for cell migration and tumor invasion
Keywords: GSK3، glycogen synthase kinase 3; Akt, v-Akt murine thymoma viral oncogene homolog product; CDC42, cell division cycle 42; DGKs, diacylglycerol kinases; ECM, extracellular matrix; EGF, Epidermal Growth Factor; FA, focal adhesions; GSK3, glycogen synthase kinase 3; HM, hydrophobic motif; I
CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics
Keywords: GSK3، glycogen synthase kinase 3; MT, microtubule; GSK3, glycogen synthase kinase 3; GFP, green fluorescent protein; EM, electron microscopy; ITC, isothermal titration calorimetrycrystal structure; microtubule; microtubule-associated protein (MAP); + TIPs; molecular modeling
Structure–activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201
Keywords: GSK3، glycogen synthase kinase 3; ArPIKfyve, associated regulator of PIKfyve; DNLC, direct nanoflow liquid chromatography; GSK3, glycogen synthase kinase 3; IBD, inflammatory bowel disease; IFN-γ, interferon-gamma; IL-12, interleukin-12; LPS, lipopolysaccharide; mTOR, mammalian target of
TaSK5, an abiotic stress-inducible GSK3/shaggy-like kinase from wheat, confers salt and drought tolerance in transgenic Arabidopsis
Keywords: GSK3، glycogen synthase kinase 3; Triticum; Arabidopsis; Cold; Drought; Salt; Signal transductionABA, abscisic acid; CA, cold acclimated; G6PD, glucose-6-phosphate dehydrogenase; GSK3, glycogen synthase kinase 3; LD, long day; NA, non acclimated; ROS, reactive oxygen species; SGG, shaggy-
2-Methoxystypandrone ameliorates brain function through preserving BBB integrity and promoting neurogenesis in mice with acute ischemic stroke
Keywords: GSK3، glycogen synthase kinase 3; 2-MS, 2-methoxystypandrone; BBB, blood–brain barrier; Bcl-2, B-cell lymphoma 2; COX-2, cyclooxygenase-2; DCX, doublecortin; GSK3, glycogen synthase kinase 3; iNOS, inducible nitric oxide synthase; I/R, ischemia reperfusion; MCAO, middle cerebral artery oc
Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3
Keywords: GSK3، glycogen synthase kinase 3; α-KI, GSK3α21A/21A knock-in; β-KI, GSK3β9A/9A knock-in; CT, circadian time; C57, C57BL/6J; DD, constant dark; DKI, GSK3α21A/21A/β9A/9A knock-in; EGTA, ethylene glycol tetraacetic acid; GSK3, glycogen synthase kinase 3; HEPES, 4-(2-hydroxyethyl)-1-piperazi
Effects of PTEN inhibition on regulation of tau phosphorylation in an okadaic acid-induced neurodegeneration model
Keywords: GSK3، glycogen synthase kinase 3; OA, okadaic acid; GSK3, glycogen synthase kinase 3; NFTs, neurofibrillary tangles; PTEN, phosphatase and tensin homologue deleted on chromosome 10; AD, Alzheimer's disease; PI3K, phosphoinositide 3-kinasePTEN; Akt/PKB; Glycogen synthase kinase 3; Alzheime
Glycogen synthase kinase 3-specific inhibitor AR-A014418 decreases neuropathic pain in mice: Evidence for the mechanisms of action
Keywords: GSK3، glycogen synthase kinase 3; AMPT, alpha-methyl-p-tyrosine; AR-A014418, N-(4-methoxybenzyl)-N0-(5-nitro-1,3-thiazol-2-yl)urea; DMSO, dimethylsulfoxide; GSK3, glycogen synthase kinase 3; IL-10, interleukin-10; IL1-ra, interleukin-1ra; IL-1β, interleukin-1β; IL-6, interleukin- 6; L-NOA
GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) β1-induced senescence
Keywords: GSK3، glycogen synthase kinase 3; GSK3, glycogen synthase kinase 3; ROS, reactive oxygen species; SA-β-gal, senescence-associated β galactosidase activity; TGF β1, transforming growth factor β1; DCF, dichlorofluorescin diacetate; DNP, 2,4-dinitrophenol; TMPD, N,N,N′,N′-tetramethyl-p-pheny
The role of Cdk5 in cognition and neuropsychiatric and neurological pathology
Keywords: GSK3، glycogen synthase kinase 3; ADBE, activity-dependent bulk endocytosis; CaMKII, Ca2+/calmodulin-dependent protein kinase; CDE, clathrin-dependent endocytosis; Cdk5, cyclin-dependent kinase 5; GSK3, glycogen synthase kinase 3; HDAC1, histone deacetylase 1; LTP, long-term potentiation;
The role of Hedgehog signaling in fibrogenic liver repair
Keywords: GSK3، glycogen synthase kinase 3; BDL, bile duct ligation; BMP, bone morphogenic protein; CCl4, carbon tetrachloride; CSK, casein kinase; Dhh, desert Hedgehog; EGF, epidermal growth factor; EMT, epithelial-to-mesenchymal transition; Gli, glioblastoma; GSK3, glycogen synthase kinase 3; Hh,
Transcription dynamics in a physiological process: β-Catenin signaling directs liver metabolic zonation
Keywords: GSK3، glycogen synthase kinase 3; PC, pericentral; PP, periportal; Apc, adenomatous polyposis coli; Gs, glutamine synthetase; CK1, Caseine Kinase 1; GSK3, Glycogen Synthase Kinase 3; Lef/Tcf, lymphoid enhancer factor/T-cell factor; β-TrCP, β-transducin repeat containing protein; LRP5/6, l
Molecular function of microtubule-associated protein 2 for filial imprinting in domestic chicks (Gallus gallus domesticus)
Keywords: GSK3، glycogen synthase kinase 3; GSK3, glycogen synthase kinase 3; IMM, intermediate medial mesopallium; RNAi, RNA interference; MAP2, microtubule-associated protein 2; miRNA, microRNA; EmGFP, emerald green fluorescence protein; PKA, protein kinase A; CMV, cytomegalovirus; RT, reverse tr
α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes
Keywords: GSK3، glycogen synthase kinase 3; CSF, cerebrospinal fluid; CNS, central nervous system; FLICA, fluorochrome-labelled inhibitors of caspase; GSK3, glycogen synthase kinase 3; 7KC, 7-ketocholesterol; Mcl-1, myeloid cell leukemia-1; MS, multiple sclerosis; TUNEL, Terminal deoxynucleotidyl t
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors [1]
Keywords: GSK3، glycogen synthase kinase 3; Imidazo[2,1-b]thiazole; Guanylhydrazones; Antitumor activity; RSK2RSK2, p90 ribosomal S6 kinase 2; GSK3, glycogen synthase kinase 3; NCI, National Cancer Institute; DTP, Developmental Therapeutics Program; DMSO, dimethylsulphoxide; GI, growth inhibition;
Effects of heat exposure on Akt/S6K1 signaling and expression of genes related to protein and energy metabolism in chicken (Gallus gallus) pectoralis major muscle
Keywords: GSK3، glycogen synthase kinase 3; Akt or PKB, protein kinase B; atrogin-1 or MAFbx, muscle atrophy F box; C2, proteasome C2 subunit also called proteasome α1 subunit; Cs, ribosomal capacity; GP, glycolytic potential; GSK3, glycogen synthase kinase 3; MuRF1, muscle ring finger-1; Nutr, nut
Cancer metabolism: The Warburg effect today
Keywords: GSK3، glycogen synthase kinase 3; CL, cardiolipin; EGFR, endothelial growth factors receptor; ETC, electron transport chain; FDG, 18Fluoro-deoxy-glucose; F2,6BP, fructose 2,6-bisphosphate; GLUT, glucose facilitative transporter; GSK3, glycogen synthase kinase 3; HIF-1, hypoxia inducible f
Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway
Keywords: GSK3، glycogen synthase kinase 3; Ci, Cubitus interruptus; CK1, Casein Kinase 1; FCS, fetal-calf serum; Fu, Fused; GSK3, Glycogen Synthase Kinase 3; IP, immunoprecipitation; KB, kinase buffer; NE, nuclear extract; PKA, Protein Kinase A; PEI, polyethylenimine; PIC, protease inhibitor cockt
The role of the mitochondrial permeability transition pore in heart disease
Keywords: GSK3، glycogen synthase kinase 3; ANT, Adenine nucleotide translocase; BKA, bongkrekic acid; CAT, carboxyatractyloside; CsA, cyclosporin A; CyP, cyclophilin; GSK3, glycogen synthase kinase 3; IP, ischaemic pre-conditioning; mitoKATP, mitochondrial ATP-dependent potassium channels; mPTP, m
Estradiol, insulin-like growth factor-I and brain aging
Keywords: GSK3، glycogen synthase kinase 3; Estrogen receptors; Glycogen synthase kinase 3; Hormonal replacement therapy; IGF-I receptor; Phosphotidylinositol 3-kinase; TauERE, estrogen response elements; ERKs, extracellular-regulated kinases; GSK3, glycogen synthase kinase 3; HPA, hypothalamo–pitu
Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation
Keywords: GSK3، glycogen synthase kinase 3; βGal, beta-galactosidase; ERK1/2, extracellular signal-regulated kinases 1 and 2; GLP-1, glucagon-like peptide 1; GSK3, glycogen synthase kinase 3; PI3K, phosphatidylinositol 3-kinase; PKB (Akt), protein kinase B; PtdIns(3,4,5)P3, phosphatidylinositol 3,4
Role of glycogen synthase kinase 3 in squamous differentiation induced by cigarette smoke in porcine tracheobronchial epithelial cells
Keywords: GSK3، glycogen synthase kinase 3; AP-1, activator protein-1; BSA, bovine serum albumin; CS, cigarette smoke; CSE, cigarette smoke extract; GSK3, glycogen synthase kinase 3; LiCl, lithium chloride; PKB, protein kinase B; PTBEC, porcine tracheobronchial epithelial cellGlycogen synthase kina
U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases
Keywords: GSK3، glycogen synthase kinase 3; Aβ, β-amyloid; AD, Alzheimer's disease; AFC, aminotrifluoromethylcoumarin; ANOVA, analysis of variance; DAVID, Database for Annotation, Visualization, and Integrated Discovery; ER, endoplasmic reticulum; GSK3, glycogen synthase kinase 3; MAPK, mitogen-act