Keywords: GSSG، گلوتاتیون دی سولفید; BCA, bicinchoninic acid; CoNPs, nanoparticles of cobalt oxide; DCFH-DA, 2,7-dichlorodihydrofluorescein diacetate; EC, endothelial cells; FSC, forward scatter; GSH, glutathione; GSSG, glutathione disulfide; HAECs, human aortic endothelial cells; HO-1, heme
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Keywords: GSSG، گلوتاتیون دی سولفید; CAT, catalase; CUR, curcumin; ER, endoplasmic reticulum; GPx, glutathione peroxidase; G6PD, glutathione-6-phosphate dehydrogenase; GR, glutathione reductase; GSH, glutathione; GSSG, glutathione disulfide; GST, glutathione S-transferase; 3β-HSD, 3β-hydroxy
Keywords: GSSG، گلوتاتیون دی سولفید; ABC, ATP Binding Cassette; ALK, activin receptor-like kinase; BBB, blood–brain barrier; BCRP, Breast Cancer Resistance Protein; CNS, central nervous system; GSH, glutathione; GSSG, glutathione disulfide; JAM, junctional adhesion molecule; MAGUK, membrane-
Keywords: GSSG، گلوتاتیون دی سولفید; ER, endoplasmic reticulum; ERO1, ER oxidoreductin 1; GSH, glutathione; GSSG, glutathione disulfide; PDI, protein disulfide isomerase; TRX, thioredoxinDisulfide bond; Glutathione; PDI; Protein storage organelle; Rice
Keywords: GSSG، گلوتاتیون دی سولفید; ANOVA, analysis of variance; EGTA, ethylene glycol-bis(2-aminoethylether-)N,N,N′,N′-tetraacetic acid; GSH, glutathione; GSSG, glutathione disulfide; GSx, total glutathione; H33342, Hoechst 33342; IB, incubation buffer; LDH, lactate dehydrogenase; Mrp1, mu
Keywords: GSSG، گلوتاتیون دی سولفید; GSSG, glutathione disulfide; GSH, glutathione; DDAB, dimethyldioctadecylammonium bromide; PBS, phosphate buffered saline; FBS, fetal bovine serum; BBB, blood-brain barrierGlutathione disulfide; Liposomes; Glutathionylation; Oxidative stress; Thiols
Keywords: GSSG، گلوتاتیون دی سولفید; AGEs, advanced glycation end products; Glo1, glyoxalase 1; Glo2, glyoxalase 2; GSH, reduced glutathione; GSSG, glutathione disulfide; MG, methylglyoxal; Pf, Plasmodium falciparumGlyoxalase; Inhibitor; Redox; Pharmacokinetics; Erythrocyte; Malaria
Keywords: GSSG، گلوتاتیون دی سولفید; MeHg, Methylmercury; iHg, inorganic mercury; GSH, reduced glutathione; GSSG, glutathione disulfide; Grx1, glutaredoxin 1; Gpx1, glutathione peroxidase 1; Nrf2, Nuclear factor (erythroid-derived 2)-like 2; GS, glutathione synthetase; SdhC, succinate dehydr
Pitfalls in the analysis of the physiological antioxidant glutathione (GSH) and its disulfide (GSSG) in biological samples: An elephant in the room
Keywords: GSSG، گلوتاتیون دی سولفید; ECNICI, electron-capture negative-ion chemical ionization; EI, electron ionization; GSH, glutathione; tGSH, total GSH; GR, GSSG reductase; GSSG, glutathione disulfide; IAA, iodoacetamide; NEM, N-ethylmaleimide; PFPA, pentafluoropropionic anhydride; 2-VP,
Influence of glutathione availability on cell damage induced by human immunodeficiency virus type 1 viral protein R
Keywords: GSSG، گلوتاتیون دی سولفید; CFU, colony forming unit; COX, cytochrome c oxidase; DHA, dehydroascorbic acid; ETC, electron transport chain; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GSH, glutathione; GSSG, glutathione disulfide; HIV-1, human immunodeficiency virus type 1; NAC,
Protein S-glutathionlyation links energy metabolism to redox signaling in mitochondria
Keywords: GSSG، گلوتاتیون دی سولفید; PGlu, protein S-glutathionylation; H2O2, hydrogen peroxide; GSH, glutathione; GSSG, glutathione disulfide; OXPHOS, oxidative phosphorylation; ROS, reactive oxygen speciesGlutathione; Mitochondria; Redox signaling; Glutathionylation; Glutaredoxin; Hydrogen
The anthocyanin cyanidin-3-O-β-glucoside modulates murine glutathione homeostasis in a manner dependent on genetic background
Keywords: GSSG، گلوتاتیون دی سولفید; GSH, Glutathione; GSSG, Glutathione Disulfide; C3G, Cyandin-3-O-β-GlucosideOxidative stress; Anthocyanin; Cyandin-3-O-β-glucoside; Polyphenol; Antioxidant; Glutathione
Elucidation of zinc and copper induced oxidative stress, DNA damage and activation of defence system during seed germination in Cassia angustifolia Vahl
Keywords: GSSG، گلوتاتیون دی سولفید; APX, ascorbate peroxidase; CAT, catalase; GPX, guaiacol peroxidase; GR, glutathione reductase; GSH, glutathione; GSSG, glutathione disulfide; MDA, malonaldialdehyde; NBT, nitro blue tetrazolium; NADP, nicotinamide adenosine dinucleotide phosphate; PAGE, p
Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes
Keywords: GSSG، گلوتاتیون دی سولفید; ALT, alanine aminotransferase; AMAP, N-acetyl-meta-aminophenol; APAP, acetaminophen; BSO, buthionine sulfoximine; DAPI, 4′,6-diamidino-2-phenylindole; GDH, glutamate dehydrogenase; GSH, glutathione; GSSG, glutathione disulfide; JNK, c-jun-N-terminal kinas
Self-assembled betulinic acid protects doxorubicin induced apoptosis followed by reduction of ROS–TNF-α–caspase-3 activity
Keywords: GSSG، گلوتاتیون دی سولفید; Self-assembled betulinic acid; DOX; Cytotoxicity; Protective role; Reactive oxygen species; ApoptosisBA, Betulinic acid; DMSO, Dimethyl sulfoxide; DTNB, 5,5′-Dithiobis-(2-nitrobenzoic acid); GSH, Reduced glutathione; GSSG, Glutathione disulfide; H2DCFDA,
Self assembled nano fibers of betulinic acid: A selective inducer for ROS/TNF-alpha pathway mediated leukemic cell death
Keywords: GSSG، گلوتاتیون دی سولفید; BA, betulinic acid; DMSO, dimethyl sulfoxide; DTNB, 5,5′-dithiobis-(2-nitrobenzoic acid); GSH, reduced glutathione; GSSG, glutathione disulfide; H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate; HEPES, N-(2-hydroxyethyl)-piperazine-N-(2-ethanesulfonic
Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs
Keywords: GSSG، گلوتاتیون دی سولفید; NAFLD, nonalcoholic fatty liver disease; CD36, cluster of differentiation 36 (fatty acid translocase/scavenger receptor); αT, α-tocopherol; ATV, atorvastatin; TAG, triacylglycerols; GSH, reduced glutathione; GSSG, glutathione disulfide; MDA, malondialdehy
Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits
Keywords: GSSG، گلوتاتیون دی سولفید; N-acetylcysteine; Glutathione; AntioxidantNAC, N-acetyl-l-cysteine; GSH, glutathione; GCL, glutamate cysteine ligase; ROS, reactive oxygen species; GSSG, glutathione disulfide; GSH Px, glutathione peroxidises; COPD, chronic obstructive pulmonary disease;
Hydrogen peroxide metabolism and sensing in human erythrocytes: A validated kinetic model and reappraisal of the role of peroxiredoxin II
Keywords: GSSG، گلوتاتیون دی سولفید; Cat, catalase; CPTTRS, Cat/Prx2/Trx1/TrxR system; Ferri, ferricatalase; GPx1, glutathione peroxidase 1; GSH, glutathione; GSR, glutathione reductase; GSSG, glutathione disulfide; Prx2, peroxiredoxin II; PSH, Prx2 monomer with peroxidatic Cys in thiol form
Intracellular glutathione pools are heterogeneously concentrated
Keywords: GSSG، گلوتاتیون دی سولفید; DTT, Dithiothreitol; EGSH, Half cell reduction potential of glutathione; ER, Endoplasmic reticulum; GSH, Reduced glutathione; GSSG, Glutathione disulfide; [GStot], Total glutathione concentration; NEM, N-ethylmaleimide; OxD, Percentage of oxidation; PDI,
Structural and functional mosaic nature of MHC class I molecules in their peptide-free form
Keywords: GSSG، گلوتاتیون دی سولفید; MHC class I; Peptide-free form; β2 microglobulin; NMR; NK cell receptors; Refoldingβ2m, β2microglobulin; CD, circular dichroism; eMHC-I, empty MHC-I; ER, endoplasmic reticulumn; GSH, glutathione; GSSG, glutathione disulfide; HC, heavy chain; HSQC, heteron
Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents
Keywords: GSSG، گلوتاتیون دی سولفید; AKR, aldo–keto reductase; AR, aldose reductase; ARLP, AR-like protein; DTT, dithiothreitol; GSH, glutathione; GSSG, glutathione disulfide; HAHE, 3-(4-hydroxy-2-methoxyphenyl)acrylic acid 3-(3-hydroxyphenyl)propyl ester; PCMB, p-chloromercuribenzoic acid;
Methylmercury impairs motor function in early development and induces oxidative stress in cerebellar granule cells
Keywords: GSSG، گلوتاتیون دی سولفید; NBAS, Neonatal Behavioral Assessment Scale; PCBs, polychlorinated biphenyls; GPx, glutathione peroxidase; TrxR, thioredoxin reductase; GSH, glutathione; GSSG, glutathione disulfide; Nrf2, nuclear factor erythroid 2-related factor 2; AIF, apoptosis-inducin
Arsenate accumulation and arsenate-induced glutathione export in astrocyte-rich primary cultures
Keywords: GSSG، گلوتاتیون دی سولفید; DMA, dimethylarsinic acid; GSH, glutathione; GSSG, glutathione disulfide; GSx, total glutathione; H33342, Hoechst 33342; IB, incubation buffer; LDH, lactate dehydrogenase; Mrp1, multidrug resistance protein 1; PBS, phosphate-buffered saline; PI, propidium
Fly ash application in nutrient poor agriculture soils: Impact on methanotrophs population dynamics and paddy yields
Keywords: GSSG، گلوتاتیون دی سولفید; ANOVA, Analysis of variance; APX, Ascorbate peroxidase; CAT, Catalase; DAS, Day after sowing; EDTA, Ethylene di-amine tetra acetic acid; EC, Electrical conductivity; FA, Fly ash; FYM, Farm yard manure; GSSG, Glutathione disulfide; NADPH, Nicotinamide aden
Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo
Keywords: GSSG، گلوتاتیون دی سولفید; COX, cyclooxygenase; GSH, glutathione; GSSG, glutathione disulfide; GPx, glutathione peroxidase; GRd, glutathione reductase; HO-1, heme oxygenase-1; Int-407 cells, intestinal-407 cells; LDH, lactate dehydrogenase; MDA, malondialdehyde; NSAIDs, nonsteroida
Cytotoxic effects of incense particles in relation to oxidative stress, the cell cycle and F-actin assembly
Keywords: GSSG، گلوتاتیون دی سولفید; BG, background; DCFH, 2′,7′-dichlorodohydrofluorescin; DCFH-DA, 2′,7′-dichlorodohydrofluorescin diacetate; DCF, 2′,7′-dichlorefluorescin; DMSO, dimethyl sulfoxide; GSH, glutathione; GSSG, glutathione disulfide; NAC, N-acetyl-l-cysteine; PM, particulate ma
Inhibition of glutathione synthesis in brain endothelial cells lengthens S-phase transit time in the cell cycle: Implications for proliferation in recovery from oxidative stress and endothelial cell damage
Keywords: GSSG، گلوتاتیون دی سولفید; GSH, glutathione; GSSG, glutathione disulfide; H1, histone H1; cdk1, cyclin dependent kinase 1; ATM, ataxia telangiectasia mutated; chk2, checkpoint kinase 2; GAPDH, glyceraldehyde 3-phosphate dehydrogenaseNuclear-to-cytosolic GSH distribution; GSH and en
Glutathione redox potential is low and glutathionylated and cysteinylated hemoglobin levels are elevated in maintenance hemodialysis patients
Keywords: GSSG، گلوتاتیون دی سولفید; GSH, glutathione; GSSG, glutathione disulfide; HbSSG, glutathionylated hemoglobin; HbSSCy, cysteinylated hemoglobin; HD, hemodialysis; Eh, redox potential; DM, diabetes mellitus; ESRD, end-stage renal disease; Kt/V, dialysis adequacy unit; NEM, N-ethylmal
Aging-dependent changes in rat heart mitochondrial glutaredoxins—Implications for redox regulation
Keywords: GSSG، گلوتاتیون دی سولفید; GSH, reduced glutathione; GSSG, glutathione disulfide; Cys-SSG, l-cysteine–glutathione mixed disulfide; Mn-TMPyP, Mn(III) tetrakis (1-methyl-4-pyridyl) porphyrin; tetratosylate, hydroxide; DT, sodium dithionite; SSM, heart subsarcolemmal mitochondria; IFM
Effect of Kombucha, a fermented black tea in attenuating oxidative stress mediated tissue damage in alloxan induced diabetic rats
Keywords: GSSG، گلوتاتیون دی سولفید; ALX, alloxan monohydrate; ALT, alanine transaminase; ALP, alkaline phosphatase; BT, black tea; BUN, blood urea nitrogen; CAT, catalase; DAB, 3,3′-diaminobenzidine tetrahydrochloride; GSH, glutathione; GSSG, glutathione disulfide; GST, glutathione-S-transf
Characterization of global metabolic responses of glucose-6-phosphate dehydrogenase-deficient hepatoma cells to diamide-induced oxidative stress
Keywords: GSSG، گلوتاتیون دی سولفید; AMPK, AMP-activated protein kinase; Dox, Doxycycline; G6PD, Glucose-6-phosphate dehydrogenase; GCL, Glutamate cysteine ligase; Gi, shRNA against G6PD; GS, glutathione synthetase; GSH, Glutathione; GSR, Glutathione reductase; GSSG, Glutathione disulfide; L
Arabidopsis cotyledon chloroplast biogenesis factor CYO1 uses glutathione as an electron donor and interacts with PSI (A1 and A2) and PSII (CP43 and CP47) subunits
Keywords: GSSG، گلوتاتیون دی سولفید; CYO1, Arabidopsis cotyledon chloroplast biogenesis factor; Di-E-GSSG, dieosin glutathione disulfide; E-GSH, eosin glutathione; FSQ, fluorescence self-quenching; GSH, glutathione; GSSG, glutathione disulfide; LHCI and LHCII, light-harvesting chlorophyll–pr
l-2-oxothiazolidine-4-carboxylate influence on age- and heat exposure-dependent peroxidation in rat's liver and kidney
Keywords: GSSG، گلوتاتیون دی سولفید; ROS, reactive oxygen species; OTC, l-2-oxothiazolidine-4-carboxylate; GSH, glutathione; GPx, glutathione peroxidase; GR, glutathione reductase; CAT, catalase; H2O2, hydrogen peroxide; Tco, colorectal temperature; GSSG, glutathione disulfide; HO, hydroxyl
Mechanisms of glutathione disulfide efflux from erythrocytes
Keywords: GSSG، گلوتاتیون دی سولفید; MRP1, multidrug resistance associated protein 1; GSH, glutathione; GSSG, glutathione disulfide; GSX, glutathione S-conjugate; GCL, glutamine cysteine ligase; BSO, buthionine sulfoxamine; MK571, (E)-3-[[[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-[[3-dime
Expression of cytosolic NADP+-dependent isocitrate dehydrogenase in melanocytes and its role as an antioxidant
Keywords: GSSG، گلوتاتیون دی سولفید; ICDH, isocitrate dehydrogenase; IDPc, cytosolic NADP+-dependent isocitrate dehydrogenase; G6PD, glucose-6-phosphate dehydrogenase; SOD, superoxide dismutase; GPx, glutathione peroxidase; GR, glutathione reductase; GSSG, glutathione disulfide; Nrf2, nuclea
Intestinal redox biology and oxidative stress
Keywords: GSSG، گلوتاتیون دی سولفید; Cys, cysteine; CySS, cystine; GSH, glutathione; GSSG, glutathione disulfide; H2O2, hydrogen peroxide; ROS, reactive oxygen species; Trx, reduced thioredoxin; TrxSS, oxidized thioredoxinIntestinal oxidative stress; Intestinal redox biology; Luminal redox a
Regulation of prostate cancer cell invasion by modulation of extra- and intracellular redox balance
Keywords: GSSG، گلوتاتیون دی سولفید; CySS, cystine; FITC, fluorescein isothiocyanate; DTT, dithiothreitol; GSH, glutathione; GSSG, glutathione disulfide; IAA, iodoacetic acid; MMP, matrix metalloproteinase; NAC, N-acetylcysteine; •NO, nitric oxide; NOX1, NADPH oxidase 1; PrEC, normal prostat
Metabolically induced heteroplasmy shifting and l-arginine treatment reduce the energetic defect in a neuronal-like model of MELAS
Keywords: GSSG، گلوتاتیون دی سولفید; CNS, central nervous system; COX, cytochrome c oxidase; FBS, fetal bovine serum; GSSG, glutathione disulfide; GSH, glutathione; LDH, lactate dehydrogenase; MnSOD, manganese superoxide dismutase; mtDNA, mitochondrial DNA; MELAS, mitochondrial myopathy, enc
Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent
Keywords: GSSG، گلوتاتیون دی سولفید; ethaselen, 1,2-[bis(1,2-benzisoselenazolone 3(2H)-ketone)] ethane; GR, glutathione reductase; GSH, glutathione; GSH-Px, glutathione peroxidase; GSSG, glutathione disulfide; ROS, reactive oxygen species; Sec, selenocysteine; Trx, thioredoxin; TrxR, thiored
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo
Keywords: GSSG، گلوتاتیون دی سولفید; APAP, acetaminophen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GSH, glutathione; GSSG, glutathione disulfide; MDA, malondi-aldehyde; NAC, N-acetylcysteine; MALDI-TOF/TOF-MS/MS, matrix-assisted laser desorption/ionization time of flig
Tertiary butyl hydroperoxide induced oxidative damage in mice erythrocytes: Protection by taurine
Keywords: GSSG، گلوتاتیون دی سولفید; TBHP, tertiary butyl hydroperoxide; ROS, reactive oxygen species; GSH, glutathione; GSSG, glutathione disulfide; CAT, catalase; GR, glutathione reductase; GST, glutathione-S-transferase; SOD, superoxide dismutase; GPx, glutathione peroxidase; G-6-PD, gluc
Redox-sensitive YFP sensors monitor dynamic nuclear and cytosolic glutathione redox changes
Keywords: GSSG، گلوتاتیون دی سولفید; ROS, reactive oxygen species; GSH, reduced glutathione; Grx, glutaredoxin; Glr, glutathione reductase; Trx, thioredoxin; Trr, thioredoxin reductase; GSSG, glutathione disulfide; rxYFP, redox-sensitive yellow fluorescent protein; IMS, mitochondrial interme
Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis
Keywords: GSSG، گلوتاتیون دی سولفید; ALX, alloxan; CAT, catalase; DAB, 3,3′-diaminobenzidine tetrahydrochloride; EtBr, ethidium bromide; FACS, fluorescence activated cell sorting; GLUT4, glucose transporter type 4; GSH, glutathione; GSSG, glutathione disulfide; GST, glutathione S-transferase
The anthocyanin cyanidin-3-O-β-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: Involvement of a cAMP–PKA-dependent signaling pathway
Keywords: GSSG، گلوتاتیون دی سولفید; ROS, reactive oxygen species; C3G, cyanidin-3-O-β-glucoside; cAMP, cyclic AMP; PKA, protein kinase A; CREB, cAMP-response-element binding protein; GSH, glutathione; GSSG, glutathione disulfide; GCL, glutamate–cysteine ligase; Gclc, glutamate–cysteine liga
The iron-chelating drug triapine causes pronounced mitochondrial thiol redox stress
Keywords: GSSG، گلوتاتیون دی سولفید; DFX, deferoxamine; DMEM, Dulbecco's modified Eagle's medium; DTNB, 5,5′-dithiobis(2-nitrobenzoic) acid; Fe, iron; GSH, reduced glutathione; GSSG, glutathione disulfide; HBSS, Hank's balanced salt solution; HO, hydroxyl radical; O2−, superoxide; Prx, perox
Dequalinium induces human leukemia cell death by affecting the redox balance
Keywords: GSSG، گلوتاتیون دی سولفید; BSO, buthionine-S,R-sulfoximine; DHE, dihydroethidium; DQA, dequalinium; GSH, glutathione; GSSG, glutathione disulfide; NAC, N-acetyl-cysteine; PI, propidium iodideDQAsomes; Dequalinium; Antitumoral; Leukemia; Apoptosis; Glutathione; JNK; p38
Thiol-based redox signalling: Rust never sleeps
Keywords: GSSG، گلوتاتیون دی سولفید; Arg, arginine; Cys, cysteine; ER, endoplasmic reticulum; Grx, glutaredoxin; GSH, glutathione; GSHR, glutathione reductase; GSSG, glutathione disulfide; GST, glutathione S-transferase; Lys, lysine; NO, nitric oxide; PDB, Protein Data Bank; PDI, protein dis
Efficient reduction of Cys110 thiyl radical by glutathione in human myoglobin
Keywords: GSSG، گلوتاتیون دی سولفید; Cys, cysteine; Mb, myoglobin; WT, wild type; GSH, reduced glutathione; GSSG, glutathione disulfide; DMPO, 5,5-dimethyl-1-pyrroline N-oxide; TEMPO, 2,2,6,6-tetramethylpiperidine-N-oxyl; MALDI-TOF, matrix-assisted laser desorption/ionization-time-of-flightH
Glutathione modulates the toxicity of, but is not a biologically relevant reductant for, the Pseudomonas aeruginosa redox toxin pyocyanin
Keywords: GSSG، گلوتاتیون دی سولفید; CF, cystic fibrosis; EPR, electron paramagnetic resonance; GSH, glutathione; GSSG, glutathione disulfide; HDF, human dermal fibroblast; NAC, N-acetylcysteine; NADPH, nicotinamide adenine dinucleotide phosphate (reduced); PD, population doubling; ROS, reac