
Conformational changes in p47phox upon activation highlighted by mass spectrometry coupled to hydrogen/deuterium exchange and limited proteolysis
Keywords: NADPH oxidase; p47phox; H/D exchange; Limited proteolysis; Conformational changeACN, acetonitrile; phox, phagocyte oxidase; AIR, autoinhibitory region; SH3, src homology 3; PX, Phox homology; SAXS, small-angle X-ray scattering; GST, glutathione S-transfer