دانلود مقالات ISI درباره HDACi، مهار کننده هیستون داسیدلاز + ترجمه فارسی

Histone deacetylase inhibitor abexinostat affects chromatin organization and gene transcription in normal B cells and in mantle cell lymphoma

Keywords: HDACi، مهار کننده هیستون داسیدلاز; BL, Burkitt's lymphoma; CCND1, cyclin D1 gene; DNA, deoxyribonucleic acid; FISH, fluorescence in situ hybridization; HDAC, histone deacetylase; HDACi, histone deacetylase inhibitor; LCL, lymphoblastoid cell line; MCL, mantle cell lymphoma; NBL, normal B-l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Modulation of human gamma/delta T-cell activation and phenotype by histone deacetylase inhibitors

Keywords: HDACi، مهار کننده هیستون داسیدلاز; BrHPP, bromohydrin pyrophosphate; HDACi, histone deacetylase inhibitor; PHA, phytohaemagglutinin; PBMC, peripheral blood mononuclear cells; TCR, T-cell receptor; VPA, valproic acid; VPM, valpromideHistone deacetylation inhibitor; Valproic acid; Toxicity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

4-(1-Ethyl-4-anisyl-imidazol-5-yl)-N-hydroxycinnamide – A new pleiotropic HDAC inhibitor targeting cancer cell signalling and cytoskeletal organisation

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HDAC, histone deacetylase; HDACi, histone deacetylase inhibitor; Etacrox, 4-(1-ethyl-4-anisyl-imidazol-5-yl)-N-hydroxycinnamide×HClImidazoles; Hydroxamic acids; Histone deacetylase inhibitors; Microtubule acetylation; Antimetastatic activity; Transwell mi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA

Keywords: HDACi، مهار کننده هیستون داسیدلاز; Apoptosis; Rhabdomyosarcoma; HDACI; Chemotherapy; Cell deathARMS, alveolar rhabdomyosarcoma; CI, combination index; ERMS, embryonal rhabdomyosarcoma; FCS, fetal calf serum; HATs, histone acetyl transferases; HDACI, histone deacetylase inhibitor; HDACs, hi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity

Keywords: HDACi، مهار کننده هیستون داسیدلاز; RNAi, RNA interference; HDAC, Histone deacetylase; HDACi, Histone deacetylase inhibitor; mTOR, mechanistic target of rapamycin; mTORC1, mTOR complex 1; mTORC2, mTOR complex 2; LOF, loss-of-function; TRNBC, triple negative breast cancer; RSP6, ribosomal S6

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide

Keywords: HDACi، مهار کننده هیستون داسیدلاز; ADP, adenosine diphosphate; CRP, collagen related peptide; GP, glycoprotein; HDACi, histone deacetylase inhibitor; ITAM, immuno-receptor tyrosine-based activation motif; ITP, immune thrombocytopenia; PBS, phosphate buffered saline; qRT-PCR, quantitive rea

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

LBH-589 (panobinostat) potentiates fludarabine anti-leukemic activity through a JNK- and XIAP-dependent mechanism

Keywords: HDACi، مهار کننده هیستون داسیدلاز; AML, acute myelogenous leukemia; CLL, chronic lymphocytic leukemia; CTCL, cutaneous T-cell lymphoma; LBH-589, panobinostat; FdA, fludarabine; HDACI, histone deacetylase inhibitor; XIAP, X chromosome-linked inhibitor of apoptosis; JNK, c-Jun N-terminal kin

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HDAC inhibitor; dopamine; neuroprotection; valproateAcH3 Lys 9, acetylated histone 3 lysine 9; DA, dopamine; DAergic, dopaminergic; GSK3-β, glycogen synthase kinase-3β; HDAC, histone deacetylase; HDACi, histone deacetylase inhibitor; HPLC, high-pressure l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

C/EBPα and PU.1 are involved in distinct differentiation responses of acute promyelocytic leukemia HL-60 and NB4 cells via chromatin remodeling

Keywords: HDACi، مهار کننده هیستون داسیدلاز; Leukemia; Differentiation; Histone deacetylase inhibitors; Transcription factorsAPL, acute promyelocytic leukemia; RA, all-trans retinoic acid; ChIP, chromatin immunoprecipitation; HDACI, histone deacetylase inhibitor; NBT, nitro blue tetrazolium; PMA, ph

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: More than just AKT inhibition

Keywords: HDACi، مهار کننده هیستون داسیدلاز; mTORC1, mTOR complex 1; AMPK, AMP-activated protein kinase; AICAR, 5-Aminoimidazole-4-carboxamide ribotide; JNK, c-Jun N-terminal kinases; ERK, extracellular signal-regulated kinase; ROS, reactive oxygen species; HDACi, histone deacetylase inhibitor; ACC,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

VDR microRNA expression and epigenetic silencing of vitamin D signaling in melanoma cells

Keywords: HDACi، مهار کننده هیستون داسیدلاز; 5-Aza, 5-azacytidine; DNMTI, DNA methyltransferase inhibitor; HDACI, histone deacetylase inhibitor; microRNA, micro messenger ribonucleic acid; mRNA, messenger ribonucleic acid; PCR, polymerase chain reaction; RXR, retinoid-X receptor; TSA, trichostatin A

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Notch- and vitamin D signaling in 1,25(OH)2D3-resistant glioblastoma multiforme (GBM) cell lines

Keywords: HDACi، مهار کننده هیستون داسیدلاز; 5-aza, 5-azacytidine; Dll, Delta-like; 1,25(OH)2D3, 1,25-dihydroxyvitamin D3; DNMTI, DNA-methyltransferase inhibitor; GBM, glioblastoma multiforme; HDACI, histone deacetylase inhibitor; jag, Jagged; PCR, polymerase chain reaction; TSA, trichostatin ANotch

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Suberoylanilide hydroxamic acid partly reverses resistance to paclitaxel in human ovarian cancer cell lines

Keywords: HDACi، مهار کننده هیستون داسیدلاز; ELISA, enzyme-linked immunosorbent assay; BCI, Berenbaum's combination index; FCS, fetal calf serum; HDACI, histone deacetylase inhibitor; HDAC6, histone deacetylase 6; PBS, phosphate-buffered saline; PTX, paclitaxel; SAHA, suberoylanilide hydroxamic acid

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

High content analysis of histone acetylation in human cells and tissues

Keywords: HDACi، مهار کننده هیستون داسیدلاز; VPA, Valproic acid; HDACi, Histone deacetylase inhibitor; TSA, Trichostatin A; FBS, Foetal bovine serum; DMSO, Dimethyl sulfoxide; PBS-T, Phosphate buffered saline and Triton X-100; PVDF, Polyvinylidene difluoride membrane; ECL, Enhanced chemiluminescence

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis

Keywords: HDACi، مهار کننده هیستون داسیدلاز; CIA, collagen-induced arthritis; Treg, regulatory T cell; VPA, valproic acid; HDACi, histone deacetylase inhibitor; PIP, proximal interphalangeal; Teff, T effectorT cell; Suppression; Autoimmunity; Rheumatoid arthritis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

HDAC inhibitors, MS275 and SBHA, enhances cytotoxicity induced by oxaliplatin in the colorectal cancer cell lines

Keywords: HDACi، مهار کننده هیستون داسیدلاز; CI, combination index; HDACi, histone deacetylase inhibitor; CRC, colorectal cancer; DRI, dose-reduction index; IC, inhibitory concentration; Fa, fraction affected (level of cytotoxicity); OXA, oxaliplatin; PI, propidium iodide; SBHA, suberic bishydroxama

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Trichostatin A sensitizes human ovarian cancer cells to TRAIL-induced apoptosis by down-regulation of c-FLIPL via inhibition of EGFR pathway

Keywords: HDACi، مهار کننده هیستون داسیدلاز; EGFR, epidermal growth factor receptor; TSA, trichostatin A; HDACI, histone deacetylase inhibitor; PARP, poly(ADP-ribose) polymerase; ERK, extracellular signal-regulated kinase; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; DR4, death re

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Epigenetic mechanisms in glioblastoma multiforme

Keywords: HDACi، مهار کننده هیستون داسیدلاز; 5-aza, 5-aza-2′-deoxycytidine; CGI, CpG island; DNMT, DNA methyltransferase; GBM, glioblastoma multiforme; HDAC, histone deacetylase; HDACi, histone deacetylase inhibitor; ICF, immunodeficiency, centromere instability and facial anomalies; LOI, loss of im

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Novel Tag-and-Exchange (RMCE) Strategies Generate Master Cell Clones with Predictable and Stable Transgene Expression Properties

Keywords: HDACi، مهار کننده هیستون داسیدلاز; CHO, Chinese hamster ovary; GOI, gene of interest; FRT, Flp recognition target; RMCE, recombinase-mediated cassette exchange; FACS, fluorescence-activated cell sorting; S/MAR, scaffold/matrix attachment region; HDACi, histone deacetylase inhibitor; NaBu,

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2009 سفارش ترجمه

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HDACI, histone deacetylase inhibitor; AML, acute myelogenous leukemia; ALL, acute lymphoblastic leukemia; PDGFR, platelet derived growth factor receptor; FLT3, fms-like tyrosine kinase 3AML; FLT3; HSP90; HDAC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

AN-113, a novel prodrug of 4-phenylbutyrate with increased anti-neoplastic activity in glioma cell lines

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HDACI, histone deacetylase inhibitor; PB, 4-phenylbutyrate; BA, butyric acid; FA, formaldehyde; AN-113, butyroyloxymethyl-4-phenylbutyrate; MG, malignant glioma; DSB, double-strand breaksAN-113; HDAC inhibitor; Glioma; Radiation potentiation; γ-H2AX

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Antifibrogenic effects of histone deacetylase inhibitors on pancreatic stellate cells

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HDACI, histone deacetylase inhibitor; PSC, pancreatic stellate cell; VPA, sodium valproate; TSA, trichostatin A; BrdU, 5-bromo-2′-deoxyuridine; α-SMA, α-smooth muscle actin; ECM, extracellular matrix; HSC, hepatic stellate cell; PDGF, platelet-derived gro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

HIV-1 protease inhibitors do not interfere with provirus transcription and host cell apoptosis induced by combined treatment TNF-α + TSA

Keywords: HDACi، مهار کننده هیستون داسیدلاز; HIV-1 protease inhibitor; NF-κB; ApoptosisHIV-1, human immunodeficiency virus type 1; LTR, long terminal repeat; HDACi, histone deacetylase inhibitor; TNFα, tumor necrosis factor alpha; IL-1, interleukin-1; HAART, highly active anti-retroviral therapy; PI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines

Keywords: HDACi، مهار کننده هیستون داسیدلاز; TSA, Trichostatin A; 5-azaCdR, 5-aza-deoxycytidine; HDACi, histone deacetylase inhibitor; HAT, histone acetyltransferase; DNMT, DNA methyltransferaseHistone deacetylase inhibitor; Tumor suppressor gene; DNA methylation; Histone acetylation; Hypomethylatio

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه